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Fer protein is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases.
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Human Monoclonal FER Primary Antibody pour IF, IHC - ABIN966133
Li, Cheng, Ling: Isolation and characterization of Fe(III)-chelate reductase gene LeFRO1 in tomato. dans Plant molecular biology 2004
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Human Monoclonal FER Primary Antibody pour ICC, IHC - ABIN969133
Girault, Greengard: The neurobiology of dopamine signaling. dans Archives of neurology 2004
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Data show that FER tyrosine kinase (Montrer TXK Anticorps) (Fer/FerT) activity was disrupted by E260, which selectively evokes metabolic stress in cancer cells by imposing mitochondrial dysfunction and deformation.
We propose a model for the regulation of Fer based on an intramolecular interaction and the curvature-dependent membrane binding mediated by its intrinsically disordered region.
Many human tumor types and cancer cell lines express the MAN2A1 (Montrer MAN2A1 Anticorps)-FER fusion, which increases proliferation and invasiveness of cancer cell lines and has liver oncogenic activity in mice.
Fer serves as a crucial mediator and amplifier of Src (Montrer SRC Anticorps)-induced tumor progression.
FER encodes a cytosolic non-receptor tyrosine kinase (Montrer TNK1 Anticorps) that influences neutrophil chemotaxis and endothelial permeability.
Fer contributes to aberrant androgen receptor (Montrer AR Anticorps) signaling via pSTAT3 cross-talk during castrate-resistant prostate cancer progression.
Detection of PJA2 (Montrer PJA2 Anticorps)-FER fusion mRNA is correlated with poor postoperative survival periods in non-small cell lung cancer.
data show that Fer kinase is elevated in non-small cell lung cancer tumors and is important for cellular invasion and metastasis
FER kinase promotes breast cancer metastasis by regulating alpha6- and beta1-integrin-dependent cell adhesion and anoikis resistance.
Fer expression correlates with renal cell carcinoma (Montrer MOK Anticorps) cell proliferation both in vitro and in vivo, and with tumor progression and survival
Sperm from mice targeted with a kinase-inactivating mutation in Fer failed to undergo capacitation-associated increases in tyrosine phosphorylation.
levels of FER were elevated in ovarian cancer cell lines relative to those in immortalized normal surface epithelial cells and that suppression of FER attenuated the motility and invasive properties of these cancer cells
directed mitochondrial accumulation of FerT endowed nonmalignant cells with tumor-forming ability
a critical role of Fer in PDGF (Montrer PDGFA Anticorps)-BB-induced STAT3 (Montrer STAT3 Anticorps) activation and cell transformation.
Fer is a novel inhibitory kinase for neutrophil chemotaxis toward end target chemoattractants through modulation of PI3K activity.
FER kinase plays a critical role in oocyte meiotic spindle microtubule dynamics and may have an additional function in GVBD.
NRP1 (Montrer NRP1 Anticorps) has a role in signaling Sema3A (Montrer SEMA3A Anticorps)-evoked neuronal death through Fer in cortical neurons
Endotoxin-induced leukocyte adhesion and emigration are significantly elevated in Fer-mutant mice relative to wild-type mice and demonstrate an essential role for Fer kinase in regulating inflammation-induced leukocyte emigration.
association of cadherin with beta-catenin (Montrer CTNNB1 Anticorps) requires the non-receptor tyrosine-kinase (Montrer TNK1 Anticorps) Fer
Fer sustains the activation of ERK1/2 and increases the production of VEGF (Montrer VEGFA Anticorps) in hypoxic cells
Fer protein is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors.
feline encephalitis virus-related kinase FER
, fujinami poultry sarcoma/Feline sarcoma-related protein Fer
, phosphoprotein NCP94
, protein phosphatase 1, regulatory subunit 74
, proto-oncogene c-Fer
, tyrosine kinase 3
, tyrosine-protein kinase Fer
, proto-oncogene tyrosine-protein kinase FER
, tyrosine protein kinase FLK
, tyrosine-protein kinase FLK
, fer (fps/fes related) tyrosine kinase (phosphoprotein NCP94)
, protein tyrosine kinase fer
, proto-oncogene tyrosine-protein kinase Fer
, fer (fps/fes related) tyrosine kinase