anti-Family with Sequence Similarity 38, Member B (FAM38B) Anticorps

Piezos are large transmembrane proteins conserved among various species, all having between 24 and 36 predicted transmembrane domains.

afficher tous les anticorps Gène GeneID UniProt
FAM38B 63895 Q9H5I5
FAM38B 667742 Q8CD54
FAM38B 307380  
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Top anti-Family with Sequence Similarity 38, Member B Anticorps sur anticorps-enligne.fr

Showing 10 out of 61 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-FAM38B Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  721_B cell lysate PIEZO2 is supported by BioGPS gene expression data to be expressed in 721_B 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: PIEZO2 Antibody [NBP1-89892] - Staining of human gall bladder shows strong membrane and cytoplasmic positivity in glandular cells. Immunocytochemistry/Immunofluorescence: PIEZO2 Antibody [NBP1-89892] - Staining of human cell line HeLa shows positivity in nucleus, cytoplasm & vesicles. Antibody staining is shown in green. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$491.63
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: PIEZO2 Antibody [NBP1-78538] - PIEZO2 antibody was tested at 1:100 in A431 cells with FITC (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). Immunohistochemistry: PIEZO2 Antibody [NBP1-78538] - Analysis of PIEZ02 in mouse epidermis using DAB with hematoxylin counterstain. 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$485.88
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p) Immunohistochemistry: PIEZO2 Antibody [NBP1-78624] - Analysis of PIEZ02 in mouse epidermis using DAB with hematoxylin counterstain. Immunocytochemistry/Immunofluorescence: PIEZO2 Antibody [NBP1-78624] - PIEZO2 antibody was tested at 1:50 in A431 cells with FITC (green) .Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$485.88
Détails
Boeuf (Vache) Lapin Inconjugué WB Host:  Rabbit  Target Name:  PIEZO2  Sample Type:  293T Whole Cell lysates  Antibody Dilution:  1.0ug/ml 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué EIA, WB Western blot analysis of FAM38B Antibody (C-term) in CEM cell line lysates (35ug/lane). This demonstrates the FAM38B antibody detected the FAM38B protein (arrow). 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué WB FAM38B Antibody (C-term)  western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the FAM38B antibody detected the FAM38B protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Lapin Inconjugué WB Western blot analysis in CEM cell line lysates (35ug/lane). 400 μL Connectez-vous pour afficher 2 to 3 Days
$515.63
Détails
Humain Lapin Inconjugué ELISA, WB Western Blot: PIEZO2 Antibody  - Analysis of PIEZO2 in SK-N-SH cell lysate with PIEZO2 antibody at (A) 1 and (B) 2 ug/mL. 0.1 mg Connectez-vous pour afficher 8 to 11 Days
$485.88
Détails

FAM38B Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
Human , ,


, , , , , , , , , , , , ,
Mouse (Murine) ,


, , , , , , , , , ,
Rat (Rattus)


anti-Family with Sequence Similarity 38, Member B Anticorps mieux référencés

  1. Human Polyclonal FAM38B Primary Antibody pour ICC, IF - ABIN4345486 : Florez-Paz, Bali, Kuner, Gomis: A critical role for Piezo2 channels in the mechanotransduction of mouse proprioceptive neurons. dans Scientific reports 2016 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal FAM38B Primary Antibody pour ICC, IF - ABIN4345484 : Lee, Leddy, Chen, Lee, Zelenski, McNulty, Wu, Beicker, Coles, Zauscher, Grandl, Sachs, Guilak, Liedtke: Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage. dans Proceedings of the National Academy of Sciences of the United States of America 2014 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal FAM38B Primary Antibody pour ICC, IF - ABIN4345487 : Poole, Herget, Lapatsina, Ngo, Lewin: Tuning Piezo ion channels to detect molecular-scale movements relevant for fine touch. dans Nature communications 2014 (PubMed)

Plus d’anticorps contre Family with Sequence Similarity 38, Member B partenaires d’interaction

Human Family with Sequence Similarity 38, Member B (FAM38B) interaction partners

  1. This study identified Piezo2 mechanosensitive cationic channel as a transducer of environmental physical cues into mechanobiological responses.

  2. The present results demonstrate the occurrence of Piezo2 in cutaneous sensory nerve formations that functionally work as slowly adapting (Merkel cells) and rapidly adapting (Meissner's corpuscles) low-threshold mechanoreceptors and are related to fine and discriminative touch but not to vibration or hard touch

  3. Study demonstrate the splicing of Piezo2 to be cell type specific. Biophysical characterization revealed substantial differences in ion permeability, sensitivity to calcium modulation, and inactivation kinetics among Piezo2 splice variants.

  4. we report the developmental phenotypic spectrum of familial Gordon syndrome in one family due to the previously characterized PIEZO2 mutation c.8057G>A.

  5. Enterochromaffin cells in the human and mouse small bowel GI epithelium selectively express the mechanosensitive ion channel Piezo2, and also that activation of Piezo2 by force leads to inward currents, 5-HT (Montrer DDC Anticorps) release and an increase in mucosal secretion

  6. The Piezo2 convert a variety of mechanical stimuli into channel activation and subsequent inactivation, and what molecules and mechanisms modulate Piezo function.

  7. we report a consanguineous family with three siblings who showed short stature, scoliosis, gross motor impairment, and a progressive form of contractures involving the distal joints that is distinct from that found in patients with domina Recessive mutations in PIEZO2 thus appear to cause a progressive phenotype that overlaps with, while being mostly distinct from that associated with dominant mutations in the same gene

  8. Sensory ataxia and proprioception defect with dorsal column involvement together with arthrogryposis, myopathy, scoliosis and progressive respiratory failure may represent a distinct clinical phenotype, and indicate recessive mutations in PIEZO2

  9. We identified homozygous loss of function variants in PIEZO2 as the underlying cause for an autosomal-recessive distal muscular atrophy with arthrogryposis, kyphoscoliosis, and neonatal respiratory insufficiency distinct from previously described dominant PIEZO2 diseases.

  10. Our results show that PIEZO2 is a determinant of mechanosensation in humans.

Mouse (Murine) Family with Sequence Similarity 38, Member B (FAM38B) interaction partners

  1. Mechanoinsensitive ''silent'' nociceptors are characterized by the expression of the nicotinic acetylcholine receptor subunit alpha (Montrer CHRNA1 Anticorps)-3 (CHRNA3 (Montrer CHRNA3 Anticorps)); the mechanically gated ion channel PIEZO2 mediates NGF (Montrer NGFB Anticorps)-induced mechanosensitivity in these neurons.

  2. Targeted genetic deletion of Merkel cells and associated mechanosensitive Piezo2 channels in the skin was sufficient to produce alloknesis.

  3. Study demonstrate the splicing of Piezo2 to be cell type specific. Biophysical characterization revealed substantial differences in ion permeability, sensitivity to calcium modulation, and inactivation kinetics among Piezo2 splice variants.

  4. Data provide evidence that Piezo2 plays a critical role in a defined homogeneous population of proprioceptor neurons that innervate the head muscles, demonstrating that this ion channel is essential for mammalian proprioceptive mechanotransduction.

  5. Data show that Piezo2 knockdown led to decreased glioma angiogenesis and reduced vascular hyperpermeability.

  6. experiments demonstrate a role for Pericentrin (Montrer PCNT Anticorps) in modulating Piezo2 activity and membrane expression in somatosensory neurons

  7. Enterochromaffin cells in the human and mouse small bowel GI epithelium selectively express the mechanosensitive ion channel Piezo2, and also that activation of Piezo2 by force leads to inward currents, 5-HT (Montrer DDC Anticorps) release and an increase in mucosal secretion

  8. Piezo2 is an airway stretch sensor; Piezo2-mediated mechanotransduction within various airway-innervating sensory neurons is critical for establishing efficient respiration at birth and maintaining normal breathing in adult mice

  9. Astrocytes in optic nerve head express multiple mechanosensitive channels, in particular Piezo1 (Montrer PIEZO1 Anticorps) and 2. The expression of putative mechanosensitive channels in these cells may contribute to their responsiveness to traumatic or glaucomatous injury.

  10. mice lacking Piezo2 in both adult sensory neurons and Merkel cells exhibit a profound loss of touch sensation

Family with Sequence Similarity 38, Member B (FAM38B) profil antigène

Profil protéine

Piezos are large transmembrane proteins conserved among various species, all having between 24 and 36 predicted transmembrane domains. 'Piezo' comes from the Greek 'piesi,' meaning 'pressure.' The PIEZO2 protein has a role in rapidly adapting mechanically activated (MA) currents in somatosensory neurons (Coste et al., 2010

Gene names and symbols associated with FAM38B

  • piezo type mechanosensitive ion channel component 2 (PIEZO2) anticorps
  • piezo-type mechanosensitive ion channel component 2 (Piezo2) anticorps
  • 5930434P17 anticorps
  • 9030411M15Rik anticorps
  • 9430028L06Rik anticorps
  • C18orf30 anticorps
  • C18orf58 anticorps
  • Fam38b anticorps
  • Fam38b2 anticorps
  • HsT748 anticorps
  • HsT771 anticorps
  • RGD1306866 anticorps

Protein level used designations for FAM38B

family with sequence similarity 38, member B , family with sequence similarity 38, member B2 , protein PIEZO2

GENE ID SPECIES
63895 Homo sapiens
667742 Mus musculus
307380 Rattus norvegicus
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