anti-Fanconi Anemia Group A Protein (FANCA) Anticorps

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). De plus, nous expédions Fanconi Anemia Group A Protein Kits (4) et Fanconi Anemia Group A Protein Protéines (4) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
FANCA 2175 O15360
FANCA 14087 Q9JL70
FANCA 361435  
Comment commander chez anticorps-enligne
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Commandez enligne
  • orders@anticorps-enligne.fr

Top anti-Fanconi Anemia Group A Protein Anticorps sur anticorps-enligne.fr

Showing 10 out of 113 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-FANCA Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Human Spleen 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué IC, IF, IP, WB Immunofluorescent analysis of FANCA (pS1149) staining in HepG2 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of FANCA (pS1149) expression in HepG2 EGF-treated (A), SP2/0 EGF-treated (B), H9C2 EGF-treated (C) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$575.00
Détails
Humain Lapin Inconjugué ELISA, IHC, WB ABIN6269644 at 1/100 staining human heart tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. ABIN6269644 at 1/100 staining rat heart tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL Connectez-vous pour afficher 11 to 12 Days
$450.00
Détails
Humain Lapin Inconjugué IF, IHC, ELISA, WB Western blot analysis of extracts from HeLa cells treated with IGF 100ng/ml 10' and HuvEc cells treated with EGF 200ng/ml 30', using FANCA (Phospho-Ser1149) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using FANCA (Phospho-Ser1149) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using FANCA (Ab-1149) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué ELISA, IF, IHC, WB 100 μL Connectez-vous pour afficher 16 Days
$181.73
Détails
Humain Lapin Inconjugué ELISA, IHC, IHC (p) Human Uterus, Endometrium: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Connectez-vous pour afficher 7 to 9 Days
$484.00
Détails
Boeuf (Vache) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué ELISA, ICC, IF, IHC, WB Western blot analysis of Phospho-FANCA (Ser1149) using K562 whole cell lysates ABIN6278652 staining HeLa cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibod 100 μL Connectez-vous pour afficher 11 to 12 Days
$390.77
Détails
Chimpanzé Lapin Inconjugué EIA, WB   0.1 mg Connectez-vous pour afficher 8 to 11 Days
$619.30
Détails

anti-Fanconi Anemia Group A Protein Anticorps mieux référencés

  1. Human Polyclonal FANCA Primary Antibody pour IP, WB - ABIN5665644 : Hicks, Chute, Paulsen, Ragland, Howlett, Guéranger, Glover, Canman: Differential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links. dans Molecular and cellular biology 2010 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal FANCA Primary Antibody pour WB - ABIN251002 : Park, Ciccone, Beck, Hwang, Freie, Clapp, Lee: Oxidative stress/damage induces multimerization and interaction of Fanconi anemia proteins. dans The Journal of biological chemistry 2004 (PubMed)

  3. Human Polyclonal FANCA Primary Antibody pour ELISA, ICC - ABIN4309986 : Huard, Tremblay, Magron, Lévesque, Carreau: The Fanconi anemia pathway has a dual function in Dickkopf-1 transcriptional repression. dans Proceedings of the National Academy of Sciences of the United States of America 2014 (PubMed)

Plus d’anticorps contre Fanconi Anemia Group A Protein partenaires d’interaction

Human Fanconi Anemia Group A Protein (FANCA) interaction partners

  1. Mutations in the FANCA gene are associated with esophageal atresia and tracheoesophageal fistula in humans.

  2. the current study was the first to report a promoter region variation in the FANCA gene among women with breast cancer in Iran. The results of the present study confirmed the allelic variants in the FANCA promoter region as a tumor suppressor gene.

  3. we show that although FANCA S1088F protein properly localizes to the nucleus, it alters FANC complex function, enhances sensitivity to DNA damaging agents, and sensitizes cells to PARP (Montrer COL11A2 Anticorps) inhibitors in vitro and in vivo.

  4. FancA amplification and overexpression appear to be crucial for radiotherapeutic failure in head and neck squamous cell carcinomas.

  5. High resolution melting curve analysis was used to screen FANCA, and LinReg software version 1.7 was utilized for analysis of expression. RESULTS: In total, six sequence alterations were identified, which included two stop codons, two frames-shift mutations, one large deletion and one amino acid exchange. FANCA expression was downregulated in patients who had sequence alterations.

  6. Results identified homozygous mutations in FANCA and FANCP/SLX4 (Montrer BTBD12 Anticorps) genes, both located on chromosome 16, were the affected recessive FA genes in three and one family respectively. Genotyping with short tandem repeat markers and SNP arrays revealed uniparental disomy of the entire mutation-carrying chromosome 16 in all four patients.

  7. Using human and murine cells defective in FANCD2 (Montrer FANCD2 Anticorps) or FANCA and primary bone marrow cells derived from FANCD2 (Montrer FANCD2 Anticorps) deficient mice, we show that the FA pathway removes R loops and that many DNA breaks accumulated in FA cells are R loop-dependent.

  8. FANCA safeguards interphase and mitosis during hematopoiesis

  9. The I939S point mutation prevented binding to the FAAP20 subunit of the FA core complex, caused SUMOylation at K921, RNF4 (Montrer RNF4 Anticorps)-mediated polyubiquitination and degradation.

  10. A frameshifting mutation and a truncating mutation of FANCA are associated with Fanconi anemia (Montrer PALB2 Anticorps).

Mouse (Murine) Fanconi Anemia Group A Protein (FANCA) interaction partners

  1. Fanca(-/-) mice showed a skewed Vkappa gene usage.

  2. FANCA safeguards interphase and mitosis during hematopoiesis

  3. study indicates that Fanca expression during endomitosis is crucial for normal megakaryopoiesis and platelet production.

  4. Data show that Fanconi anemia complementation group A Fanca is required for the induction of transition mutations at A/T residues during somatic hypermutation (SHM (Montrer CNTNAP1 Anticorps)) and immunoglobulin (Ig) class switch recombination (CSR (Montrer SCARA3 Anticorps)).

  5. CD25 (Montrer IL2RA Anticorps)(+)Foxp3 (Montrer FOXP3 Anticorps)(+) Tregs of Fanca(-/-) or Fancd2 (Montrer FANCD2 Anticorps)(-/-) mice were less efficient in suppressing the production of GVHD-associated inflammatory cytokines.

  6. null mutations in Fanca or Fancg (Montrer FANCG Anticorps) are fully epistatic

  7. genetic diversity in FANCA, FANCC (Montrer FANCC Anticorps) and FANCL (Montrer FANCL Anticorps) does not support an association of these genes with cervical cancer susceptibility in the Swedish population.

  8. The results support a model where both FANCA and FANCC (Montrer FANCC Anticorps) are part of a multi-protein nuclear FA complex with identical function in cellular responses to DNA damage and germ cell survival.

  9. To study the in vivo role of the FA group A gene (Fanca), gene-targeting techniques were used to generate Fanca(tm1Hsc) mice in which Fanca exons 1-6 were replaced by a beta (Montrer SUCLA2 Anticorps)-galactosidase (Montrer GLB1 Anticorps) reporter construct.

  10. GnRH (Montrer GNRH1 Anticorps) induced a rapid, transient increase in Fanca mRNA.

Fanconi Anemia Group A Protein (FANCA) profil antigène

Profil protéine

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity\; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia.

Gene names and symbols associated with FANCA

  • Fanconi anemia complementation group A (FANCA) anticorps
  • Fanconi anemia, complementation group A (Fanca) anticorps
  • AW208693 anticorps
  • FA anticorps
  • FA-H anticorps
  • FA1 anticorps
  • FAA anticorps
  • FACA anticorps
  • FAH anticorps
  • FANCH anticorps

Protein level used designations for FANCA

Fanconi anemia group A protein , Fanconi anemia, complementation group H , Fanconi anemia, type 1 , Fanconi anemia group A protein homolog

GENE ID SPECIES
2175 Homo sapiens
454393 Pan troglodytes
14087 Mus musculus
415854 Gallus gallus
361435 Rattus norvegicus
Fournisseurs de qualité sélectionnés pour anti-Fanconi Anemia Group A Protein (FANCA) Anticorps
Avez-vous cherché autre chose?