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FCRL2 belongs to the Fc receptor family. De plus, nous expédions Fc Receptor-Like B Anticorps (21) et et beaucoup plus de produits pour cette protéine.
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The aim of the study was to associate multiple polymorphisms within FCGR gene locus with IgA nephropathy in a large Chinese cohort.
Expression analysis revealed FCRL2 mRNA only in placenta.FCRL2 is differentially expressed by transformed B cell lines.
Fcry is upregulated by short-term treatment with BAFF/BLyS, which promotes B cell survival rather than proliferation
a negative immunomodulatory function for FCRL2 in the regulation of memory B cells.
In FCRLB knock-out mice, B-cell developmemt and in vitro response were normal, but in vivo antibody responses to a T-dependent antigen were elevated. The latter response may be due to a promoter polymorphism in the 129/Sv knock-out strain's Fcgr2b allele.
FCRL2 belongs to the Fc receptor family. Fc receptors are involved in phagocytosis, antibody-dependent cell cytotoxicity, immediate hypersensitivity, and transcytosis of immunoglobulins via their ability to bind immunoglobulin (Ig) constant regions (Chikaev et al., 2005
Fc receptor homolog expressed in B-cells protein 2
, Fc receptor like 2
, Fc receptor-like and mucin-like 2
, fc receptor homolog expressed in B cells protein 2
, fc receptor-like and mucin-like protein 2
, fc receptor-like protein 2
, fc receptor-related protein Y
, Fc receptor related Y
, Fc receptor-like mucin-like 2