anti-Fermitin Family Member 1 (FERMT1) Anticorps

FERMT1 encodes a member of the fermitin family, and contains a FERM domain and a pleckstrin homology domain. De plus, nous expédions FERMT1 Kits (7) et FERMT1 Protéines (5) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
FERMT1 55612 Q9BQL6
FERMT1 241639 P59113
FERMT1 296179  
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Top anti-FERMT1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 54 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-FERMT1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  Human heart 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué IHC, IHC (p), WB Human Placenta (formalin-fixed, paraffin-embedded) stained with FERMT1 antibody ABIN364270 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-FERMT1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Connectez-vous pour afficher 11 to 14 Days
$727.83
Détails
Humain Lapin Inconjugué WB FERMT1 Antibody (Center) (ABIN652858) western blot analysis in Hela,HepG2 cell line lysates (35 µg/lane).This demonstrates the FERMT1 antibody detected the FERMT1 protein (arrow). Western blot analysis of FERMT1 Antibody (Center) (ABIN652858) in mouse stomach tissue lysates (35 µg/lane). FERMT1 (arrow) was detected using the purified polyclonal antibody 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Boeuf (Vache) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué WB Detection of URP1 in 20 ug of human lung adenocarcinoma cell line NCI-H322 lysate using ABIN151958. 0.1 mg Connectez-vous pour afficher 7 to 9 Days
$345.00
Détails
Humain Lapin Inconjugué WB Western blot analysis in Hela,HepG2 cell line lysates (35ug/lane). Western blot analysis of FERMT1 Antibody in mouse stomach tissue lysates (35ug/lane). 400 μL Connectez-vous pour afficher 2 to 3 Days
$515.63
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-FERMT1 / Kindlin antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100. 200 μL Connectez-vous pour afficher 11 to 14 Days
$484.00
Détails
Humain Lapin Inconjugué IP, WB Immunoprecipitation of FERMT1 transfected lysate using anti-FERMT1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with FERMT1 purified MaxPab mouse polyclonal antibody (B01P) . Western Blot analysis of FERMT1 expression in transfected 293T cell line by FERMT1 MaxPab polyclonal antibody.<br><br>Lane 1: FERMT1 transfected lysate(77.40 KDa).<br>Lane 2: Non-transfected lysate.<br> 100 μL Connectez-vous pour afficher 11 to 12 Days
$425.71
Détails
Humain Lapin Inconjugué ELISA, WB 50 μg Connectez-vous pour afficher 2 to 3 Days
$446.88
Détails

Plus d’anticorps contre FERMT1 partenaires d’interaction

Human Fermitin Family Member 1 (FERMT1) interaction partners

  1. Kindlin-1 is mainly expressed in the cytoplasm of normal esophageal squamous epithelium and Esophageal cancer (EC) cells. Kindlin-1 expression is positively correlated with tumor cell differentiation and is higher in stage I tumors. Kindlin-1 expression is higher in non-smoker patients than in smoker patients, and in patients with a family history of EC.

  2. Kindlin supports platelet GPIIB IIIA activation by interacting with paxillin (Montrer PXN Anticorps).

  3. we demonstrated that Kindlin-1 promotes CRC (Montrer CALR Anticorps) progression by recruiting SARA (Montrer ZFYVE9 Anticorps) and Smad3 (Montrer SMAD3 Anticorps) to TbetaRI (Montrer TGFBR1 Anticorps) and thereby activates TGF-beta (Montrer TGFB1 Anticorps)/Smad3 (Montrer SMAD3 Anticorps) signaling. Thus, Kindlin-1 is a novel regulator of TGF-beta (Montrer TGFB1 Anticorps)/Smad3 (Montrer SMAD3 Anticorps) signaling and may also be a potential target for CRC (Montrer CALR Anticorps) therapeutics.

  4. Sequence analysis of KIND1 exons in patient 1 revealed a commonly reported homozygous nonsense mutation in exon 6 (c.811C>T;p.R271X). Both Patients 2 and 3 had novel homozygous single nucleotide deletions

  5. these data define a novel role for Kin1 in microtubule acetylation and stability

  6. keratinocytes derived from KS patients are unable to undergo electrotaxis, and this defect is restored by overexpression of wild-type kindlin-1 but not a W612A mutation that prevents kindlin-integrin binding.

  7. FERMT1 activates the beta-catenin (Montrer CTNNB1 Anticorps) transcriptional activity to promote EMT (Montrer ITK Anticorps) in CC metastasis.

  8. KIND1 is important not only for keratinocyte proliferation but also for the suppression of UV-induced inflammation and DNA damage.

  9. We show a direct relationship between kindlin-1 abundance and UV-B induced apoptosis in keratinocytes, whereas kindlin-2 (Montrer FERMT2 Anticorps) overexpression has no compensatory effect.

  10. These results indicate that Kindlin-1 is essential in EGF (Montrer EGF Anticorps)-induced re-epithelialization in skin wound healing and provide additional rationale for the clinical application of EGF (Montrer EGF Anticorps) in the treatment of acute wounds.

Mouse (Murine) Fermitin Family Member 1 (FERMT1) interaction partners

  1. Kindlin supports platelet GPIIB IIIA activation by interacting with paxillin (Montrer PXN Anticorps).

  2. loss of Kindlin-1 leads to an imbalance in the cellular oxidative state, which renders Kindlin-1 deficient cells more prone to the effects of reactive oxygen species generated in response to oxidative stress

  3. these data define a novel role for Kin1 in microtubule acetylation and stability

  4. These results indicate that Kindlin-1 is essential in EGF (Montrer EGF Anticorps)-induced re-epithelialization in skin wound healing and provide additional rationale for the clinical application of EGF (Montrer EGF Anticorps) in the treatment of acute wounds.

  5. By modulating its affinity with kindlin, beta3 integrin (Montrer ITGB3 Anticorps) may be able to locate near the cell edge where it can control beta1 integrin activation and clustering.

  6. Kindlin-1 is highly expressed in epithelial tissues derived from ectoderm and endoderm. Kindlin-1 was also found highly expressed in endoderm/ectoderm-derived tissues in embryos.

  7. Kindlin-1 controls keratinocyte adhesion through beta1-class integrins and proliferation and differentiation of cutaneous epithelial stem cells via TGF-beta (Montrer TGFB1 Anticorps) activation and Wnt (Montrer WNT2 Anticorps)-beta-catenin (Montrer CTNNB1 Anticorps) signal inhibition.

  8. Kindlin-1 and Kindlin-2 (Montrer FERMT2 Anticorps) have opposite roles in lung cancers

  9. Kindlin-1 in mice gives rise to skin atrophy and an intestinal epithelial dysfunction with similarities to human ulcerative colitis.

  10. Kindlin-1 and -2 directly bind the C-terminal region of beta integrin cytoplasmic tails and exert integrin-specific activation effects

Xenopus laevis Fermitin Family Member 1 (FERMT1) interaction partners

  1. Kindlin1 knockdown resulted in developmental delays, gross malformations of the gut (Montrer GUSB Anticorps) and eventual lethality by tadpole stages.

Zebrafish Fermitin Family Member 1 (FERMT1) interaction partners

  1. The rof/kindlin-1 mutant zebrafish provides a unique model system to study epidermal adhesion mechanisms in vivo.

FERMT1 profil antigène

Profil protéine

This gene encodes a member of the fermitin family, and contains a FERM domain and a pleckstrin homology domain. The encoded protein is involved in integrin signaling and linkage of the actin cytoskeleton to the extracellular matrix. Mutations in this gene have been linked to Kindler syndrome.

Gene names and symbols associated with FERMT1

  • fermitin family member 1 (FERMT1) anticorps
  • fermitin family member 1 (Fermt1) anticorps
  • fermitin family member 1 S homeolog (fermt1.S) anticorps
  • fermitin family member 1 (fermt1) anticorps
  • fermitin family homolog 1 (LOC100548276) anticorps
  • 5830467P10Rik anticorps
  • C20orf42 anticorps
  • DTGCU2 anticorps
  • KIND1 anticorps
  • Kindlin-1 anticorps
  • RGD1306816 anticorps
  • si:ch73-22c10.1 anticorps
  • UNC112A anticorps
  • URP1 anticorps
  • wu:fc32b07 anticorps

Protein level used designations for FERMT1

UNC112 related protein 1 , fermitin family homolog 1 , kindlerin , kindlin 1 , kindlin syndrome protein , unc-112-related protein 1 , UNC-112 related protein 1 , fermitin family member 1 , fermitin family homolog 1-like , fc32b07

GENE ID SPECIES
55612 Homo sapiens
241639 Mus musculus
296179 Rattus norvegicus
379119 Xenopus laevis
458088 Pan troglodytes
485775 Canis lupus familiaris
524427 Bos taurus
718297 Macaca mulatta
100407542 Callithrix jacchus
416727 Gallus gallus
100332544 Danio rerio
100466357 Ailuropoda melanoleuca
100492800 Xenopus (Silurana) tropicalis
100548276 Meleagris gallopavo
100051761 Equus caballus
100157961 Sus scrofa
100732971 Cavia porcellus
Fournisseurs de qualité sélectionnés pour anti-FERMT1 (FERMT1) Anticorps
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