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Members of family C of the G protein-coupled receptor (GPCR) superfamily, such as GPRC6A, are characterized by an evolutionarily conserved amino acid-sensing motif linked to an intramembranous 7-transmembrane loop region. De plus, nous expédions GPRC6A Kits (7) et et beaucoup plus de produits pour cette protéine.
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Human Polyclonal GPRC6A Primary Antibody pour IHC (p) - ABIN270833
Harno, Edwards, Geraghty, Ward, Dodd, Dauban, Faure, Ruat, Weston: Evidence for the presence of GPRC6A receptors in rat mesenteric arteries. dans Cell calcium 2008
Show all 2 Pubmed References
Human GPRC6A is a functional osteocalcin (Montrer BGLAP Anticorps) and testosterone sensing receptor that promotes prostate cancer progression.
he nonrare polymorphism rs2274911 in the GPRC6A gene was associated with insulin (Montrer INS Anticorps) resistance features, independently of the metabolic phenotype and osteocalcin (Montrer BGLAP Anticorps) levels.
Genetic Variations in the Human G Protein-coupled Receptor (Montrer ADRA1A Anticorps) Class C, Group 6, Member A (Montrer CXCL14 Anticorps) (GPRC6A) Control Cell Surface Expression and Function
Osteocalcin (Montrer BGLAP Anticorps) and Sex Hormone Binding Globulin (Montrer SHBG Anticorps) Compete on a Specific Binding Site of GPRC6A.
results suggest that G protein-coupled receptor (Montrer ADRA1A Anticorps) class C group 6 member A (Montrer CXCL14 Anticorps)(GPRC6A) inactivation or sub-function contributes to reduced exposure to androgens, leading to cryptorchidism during fetal life and/or low sperm production in adulthood
association of the THADA, FOXP4 (Montrer FOXP4 Anticorps), GPRC6A/RFX6 (Montrer RFX6 Anticorps) and 8q24 genes with prostate cancer in Asian populations.
The present experiments demonstrated a critical role for the GPRC6A-ERK1/2 and PI3K (Montrer PIK3CA Anticorps)/Akt (Montrer AKT1 Anticorps) signaling pathway in arginine-mediated fibroblast survival.
Duox1 (Montrer DUOX1 Anticorps) activity is stimulated by testosterone through GPRC6A in skin keratinocytes
The F464Y substitution in GPRC6A may be a cause of primary testicular failure.
Extracellular Ca2 (Montrer CA2 Anticorps)+ activates the NLRP3 (Montrer NLRP3 Anticorps) inflammasome via CaSR (Montrer CASR Anticorps) and GPRC6A.
findings imply the possibility to ameliorate menopause-induced metabolic disorder by GPRC6A and adiponectin signaling
GPCR6A activation by Alum leads to the initiation of innate inflammatory responses whereas it is an important signal for the limitation of adaptive immune responses induced by Alum, partially explained by B cell IL-10 (Montrer IL10 Anticorps).
the loss of osteocalcin (Montrer BGLAP Anticorps)/Gprc6a signaling has a profound effect on beta-cell mass accrual during late pancreas morphogenesis
the GPRC6A receptor is involved in regulating exercise behaviour
Activation of GPRC6A by L-arginine (Montrer GATM Anticorps) did not stimulate insulin (Montrer INS Anticorps) secretion.
the GPRC6A receptor functions as an amino acid sensor in GLUTag cells that promotes GLP-1 (Montrer GCG Anticorps) secretion
GPRC6A is a novel molecular target for regulating prostate growth and cancer progression.
These findings suggest that GPRC6A is a candidate for mediating the response to Ocn in the bone-pancreas endocrine loop regulating insulin (Montrer INS Anticorps) signaling.
GPRC6A is functionally important in regulating non-genomic effects of androgens in multiple tissues.
Members of family C of the G protein-coupled receptor (GPCR) superfamily, such as GPRC6A, are characterized by an evolutionarily conserved amino acid-sensing motif linked to an intramembranous 7-transmembrane loop region. Several members of GPCR family C, including GPRC6A, also have a long N-terminal domain (summary by Pi et al., 2005
G protein-coupled receptor, family C, group 6, member A
, G-protein coupled receptor family C group 6 member A-like
, G-protein coupled receptor GPCR33
, G-protein coupled receptor family C group 6 member A
, predicted with SOSUI analysis
, seven transmembrane helix receptor