anti-G Protein-Coupled Receptor 4 (GPR4) Anticorps

Proton-sensing receptor coupled to several G-proteins, including G(s), G(13) and G(q)/G(11) proteins, leading to cAMP production.. De plus, nous expédions GPR4 Protéines (5) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
GPR4 2828 P46093
GPR4 319197 Q8BUD0
GPR4 308408 Q4KLH9
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Top anti-GPR4 Anticorps sur anticorps-enligne.fr

Showing 10 out of 41 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Roussette (Chauve-souris) Lapin Inconjugué IHC, IHC (p) Anti-GPR4 antibody  ABIN1048816 IHC staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Connectez-vous pour afficher 7 to 9 Days
$484.00
Détails
Chien Lapin Inconjugué IHC, IHC (p) Anti-GPR4 antibody  ABIN1048817 IHC staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Connectez-vous pour afficher 7 to 9 Days
$484.00
Détails
Chien Lapin Inconjugué ICC, IHC, IHC (p) Anti-GPR4 antibody  ABIN1048818 IHC staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Connectez-vous pour afficher 7 to 9 Days
$484.00
Détails
Humain Lapin Inconjugué WB Western Blot: GPR4 Antibody [NBP1-33619] - Sample (30 ug of whole cell lysate) A: Raji 10% SDS PAGE; antibody diluted at 1:1000. 0.1 mL Connectez-vous pour afficher 8 to 11 Days
$514.63
Détails
Humain Lapin Inconjugué WB GPR4 Antibody (Center) (ABIN1881386) western blot analysis in WiDr cell line and rat liver tissue lysates (35 µg/lane). This demonstrates the GPR4 antibody detected the GPR4 protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Chien Lapin Inconjugué ICC, IHC (p) Immunohistochemistry-Paraffin: GPR4 Antibody [NLS145] - Analysis of anti-GPR4 antibody with human lung, adenocarcinoma. Immunocytochemistry/Immunofluorescence: GPR4 Antibody [NLS145] - Analysis of anti-GPR4 antibody with untransfected HEK293 human embryonic kidney cells. 0.05 mL Connectez-vous pour afficher 10 to 13 Days
$514.63
Détails
Humain Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Chien Lapin Inconjugué IHC (p) Immunohistochemistry-Paraffin: GPR4 Antibody [NLS144] - Analysis of anti-GPR4 antibody with human kidney, renal tubules at 15 ug/ml. Immunohistochemistry-Paraffin: GPR4 Antibody [NLS144] - Analysis of anti-GPR4 antibody with human kidney, renal tubules. 0.05 mL Connectez-vous pour afficher 10 to 13 Days
$514.63
Détails
Humain Lapin Inconjugué WB   100 μL Connectez-vous pour afficher 7 to 9 Days
$507.83
Détails

GPR4 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
Human , , ,


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Mouse (Murine) ,


Rat (Rattus) ,


anti-GPR4 Anticorps mieux référencés

  1. Human Polyclonal GPR4 Primary Antibody pour WB - ABIN1881386 : Heiber, Docherty, Shah, Nguyen, Cheng, Heng, Marchese, Tsui, Shi, George: Isolation of three novel human genes encoding G protein-coupled receptors. dans DNA and cell biology 1995 (PubMed)
    Show all 4 Pubmed References

Plus d’anticorps contre GPR4 partenaires d’interaction

Human G Protein-Coupled Receptor 4 (GPR4) interaction partners

  1. Proton-sensing GPR4 signaling mediated the proton-induced inhibitory effects on the osteogenesis of BMSCs. YAP (Montrer YAP1 Anticorps) was the downstream effector of GPR4 signaling. Extracellular pH modulates the osteogenic responses of BMSCs by regulating the proton-sensing GPR4-YAP (Montrer YAP1 Anticorps) pathway.

  2. These results suggest that zOGR1, but not GPR4, is also a metal-sensing G-protein-coupled receptor (Montrer ADRA1A Anticorps) in addition to a proton-sensing G-protein-coupled receptor (Montrer ADRA1A Anticorps), although not all metals that activate hOGR1 activated zOGR1.

  3. GPR4 blockade attenuated renal injury after IR and reduced the cell apoptosis through the suppression of CHOP (Montrer DDIT3 Anticorps) expression.

  4. acidosis/GPR4-induced endoplasmic reticulum stress pathways in endothelial cells may regulate vascular growth and inflammatory response in the acidic microenvironment.

  5. it was demonstrated that GPR4 affects ECs by regulating Notch1 (Montrer NOTCH1 Anticorps), a function that may be important for physiological and pathological angiogenesis.

  6. GPR4 induces angiogenesis via GPR4-induced p38 (Montrer CRK Anticorps)-mediated IL6 (Montrer IL6 Anticorps), IL8 (Montrer IL8 Anticorps) and VEGFA (Montrer VEGFA Anticorps) secretion at acidic extracellular pH in squamous cell carcinoma of the head and neck

  7. The results suggested that GPR4 may play an important role in the development of epithelial ovarian carcinoma (EOC), and its overexpression might be required for the angiogenesis, tumor growth, and metastasis of EOC

  8. acidosis/GPR4 signaling regulates endothelial cell adhesion mainly through the G(s)/cAMP/Epac (Montrer RAPGEF3 Anticorps) pathway

  9. The mutation of histidine residue at 79, 165, or 269 from the N-terminal of GPR4 to phenylalanine shifted the half-maximal effective concentration (EC(50)) of proton-induced signaling activities to the right, including cAMP accumulation.

  10. Endogenous GPR4 in endothelial cells may be a potential G protein-coupled receptor (Montrer ADRA1A Anticorps) by which LPC (Montrer PCSK7 Anticorps) signals proinflammatory activities.

Mouse (Murine) G Protein-Coupled Receptor 4 (GPR4) interaction partners

  1. GPR4 blockade attenuated renal injury after IR and reduced the cell apoptosis through the suppression of CHOP (Montrer DDIT3 Anticorps) expression.

  2. Collectively, these results posit the acid sensor GPR4 as a novel component of central blood pressure control through interactions with the renin (Montrer REN Anticorps)-angiotensin system.

  3. knockdown of a proton-sensing G protein-coupled receptor (Montrer GPR34 Anticorps) GPR4 markedly reduced CHOP (Montrer DDIT3 Anticorps) expression and endothelial cell apoptosis after hypoxia exposure.

  4. The results indicate that through the G12 (Montrer TCF3 Anticorps)/13/Rho signaling pathway GPR4 modulates focal adhesion dynamics and reduces cell spreading and membrane ruffling.

  5. The data identify GPR4 and TASK-2 (Montrer KCNK5 Anticorps) as distinct, parallel, and essential central mediators of respiratory chemosensitivity.

  6. These results suggested that, at least in part, RANKL (Montrer TNFSF11 Anticorps) expression by osteoblasts in an acidic environment was mediated by cAMP/PKA signaling resulting from GPR4 activation.

  7. GPR4 modulates glucose homeostasis by increasing insulin (Montrer INS Anticorps) sensitivity.

  8. Reduced pathological angiogenesis and tumor growth in mice lacking GPR4, a proton sensing receptor.

  9. findings suggest that GPR4 activation by an acidic pH inhibits tumor cell migration and invasion, and the Rho GTPase (Montrer RACGAP1 Anticorps) is at least partly responsible for this phenotype

  10. These results suggest that GPR4 deficiency leads to partially penetrant vascular abnormalities during development and that this receptor functions in blood vessel pH sensing.

GPR4 profil antigène

Profil protéine

Proton-sensing receptor coupled to several G-proteins, including G(s), G(13) and G(q)/G(11) proteins, leading to cAMP production.

Gene names and symbols associated with GPR4

  • G protein-coupled receptor 4 (GPR4) anticorps
  • G protein-coupled receptor 4 (Gpr4) anticorps

Protein level used designations for GPR4

G-protein coupled receptor 19 , G-protein coupled receptor 4

GENE ID SPECIES
2828 Homo sapiens
319197 Mus musculus
308408 Rattus norvegicus
512876 Bos taurus
100144489 Sus scrofa
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