anti-G Protein-Coupled Receptor 64 (GPR64) Anticorps

GPR64 encodes a member of the G protein-coupled receptor family described as an epididymis-specific transmembrane protein.

Gène	GeneID	UniProt
GPR64	10149	Q8IZP9
GPR64	237175	Q8CJ12
GPR64	266735	Q8CJ11

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Showing 10 out of 22 products:

Catalogue No.	Reactivité	Hôte	Conjugué	Application	Quantité	Fournisseur	Livraison	Prix	Détails
ABIN270581	Hamster	Lapin	Inconjugué	IHC (p)	0.05 mL	Connectez-vous pour afficher	10 to 13 Days	$514.63	Détails
ABIN4315844	Humain	Lapin	Inconjugué	ICC, IF, IHC, IHC (p)	0.1 mL	Connectez-vous pour afficher	10 to 13 Days	$491.63	Détails
ABIN1735145	Humain	Lapin	Inconjugué	IHC (p)	50 μg	Connectez-vous pour afficher	12 to 14 Days	$685.40	Détails
ABIN4315843	Roussette (Chauve-souris)	Lapin	Inconjugué	IHC (p)	0.05 mL	Connectez-vous pour afficher	10 to 13 Days	$514.63	Détails
ABIN6244737	Humain	Mouton	Inconjugué	FACS, IHC, WB	100 μg	Connectez-vous pour afficher	8 to 9 Days	$416.30	Détails
ABIN5077032	Humain	Lapin	Inconjugué	IHC (p), WB	100 μL	Connectez-vous pour afficher	10 to 13 Days	$491.63	Détails
ABIN6244736	Humain	Souris	Inconjugué	FACS	100 μg	Connectez-vous pour afficher	9 to 11 Days	$308.20	Détails
ABIN2276265	Humain	Lapin	Inconjugué	IHC	50 μg	Connectez-vous pour afficher	11 to 16 Days	$762.14	Détails
ABIN1713500	Humain	Lapin	Inconjugué	IF (p), IHC (p), WB	100 μL	Connectez-vous pour afficher	14 to 21 Days	$306.90	Détails
ABIN6038429	Humain	Lapin	Inconjugué	ELISA, IHC	100 μL	Connectez-vous pour afficher	11 to 18 Days	$412.19	Détails

GPR64 Anticorps par réactivité, application, clonalité et conjugué

Attributs	Application	Hôte	Clonalité
Human	, , , ,	, ,	,
Mouse (Murine)	, ,	,
Rat (Rattus)	, ,	,

Plus d’anticorps contre GPR64 partenaires d’interaction

Human G Protein-Coupled Receptor 64 (GPR64) interaction partners

identified two missense variants in two congenital bilateral absence of the vas (Montrer AVP Anticorps) deferens (CBAVD) patients (c.G1709A, p.C570Y; and c.A2968G, p.K990E); study did not find any potential pathogenic CFTR (Montrer CFTR Anticorps) variants, implying the ADGRG2 variants are the genetic cause in these patients
GPR64 is expressed on the cell surface of parathyroid cells, is overexpressed in parathyroid tumors, and physically interacts with the CaSR (Montrer CASR Anticorps).
study confirms the crucial role of ADGRG2 in human male fertility and brings new insight into congenital obstructive azoospermia pathogenesis; in men with CBAVD who are CFTR (Montrer CFTR Anticorps)-negative, ADGRG2 testing could allow for appropriate genetic counseling with regard to the X-linked transmission of the molecular defect
Knockdown of ADGRG2 breast cancer cell lines resulted in a strong reduction in cell adhesion and subsequent cell migration which was associated with a selective reduction in RelB (Montrer RELB Anticorps).

Mouse (Murine) G Protein-Coupled Receptor 64 (GPR64) interaction partners

examined the G protein-coupling abilities of GPR64 and showed that it is activated through a tethered agonist sequence, which we have previously identified as the Stachel sequence
GPR64 expression in ES maintains an immature phenotype that is less sensitive to TRAIL-induced apoptosis and via its up-regulation of PGF (Montrer PTGFR Anticorps) and MMP1 (Montrer MMP1 Anticorps) orchestrates and promotes invasiveness and metastatic spread in Ewing sarcoma.
The knockout of the HE6/Gpr64 receptor was mainly associated with the downregulation of genes specific to the initial segment.
Affymetrix expression profiling shows that the C terminus of Runx2 (Montrer RUNX2 Anticorps) regulates genes involved in G protein-coupled receptor (Montrer GPR34 Anticorps) signaling Rgs2 (Montrer RGS2 Anticorps), Rgs4 (Montrer RGS4 Anticorps), Rgs5 (Montrer RGS5 Anticorps), Rgs16 (Montrer RGS16 Anticorps), Gpr23 (Montrer LPAR4 Anticorps), Gpr30 (Montrer GPER Anticorps), Gpr54 (Montrer KISS1R Anticorps), Gpr64, and Gna13 (Montrer GNA13 Anticorps).

GPR64 profil antigène

Profil protéine

This gene encodes a member of the G protein-coupled receptor family described as an epididymis-specific transmembrane protein. The encoded protein may be proteolytically processed as it contains a motif shown to be a protein scission motif in some members of this family (PMID: 11973329). Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with GPR64

adhesion G protein-coupled receptor G2 (ADGRG2) anticorps
adhesion G protein-coupled receptor G2 (Adgrg2) anticorps

AW212196 anticorps
B830041D06Rik anticorps
EDDM6 anticorps
He6 anticorps
Me6 anticorps
Re6 anticorps
TM7LN2 anticorps

Protein level used designations for GPR64

G protein-coupled receptor 64 , G-protein coupled receptor 64-like , G protein-coupled receptor, epididymis-specific (seven transmembrane family) , G-protein coupled receptor 64 , epididymal protein 6 , human epididymis-specific protein 6 , LNB-TM7 heptahelical receptor Me6 , epididymis-specific protein 6 , re6 receptor

GENE ID	SPECIES
418611	Gallus gallus
465524	Pan troglodytes
491763	Canis lupus familiaris
694495	Macaca mulatta
100031393	Monodelphis domestica
100058260	Equus caballus
100157214	Sus scrofa
100355893	Oryctolagus cuniculus
100397621	Callithrix jacchus
100467214	Ailuropoda melanoleuca
100585341	Nomascus leucogenys
10149	Homo sapiens
237175	Mus musculus
266735	Rattus norvegicus

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