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G3BP1 encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. De plus, nous expédions GTPase Activating Protein (SH3 Domain) Binding Protein 1 Protéines (12) et GTPase Activating Protein (SH3 Domain) Binding Protein 1 Kits (9) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 151 products:
Human Monoclonal G3BP1 Primary Antibody pour IF, IHC (p) - ABIN564390
Norazit, Meedeniya, Nguyen, Mackay-Sim: Progressive loss of dopaminergic neurons induced by unilateral rotenone infusion into the medial forebrain bundle. dans Brain research 2010
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Human G3BP1 Primary Antibody pour IHC - ABIN966168
Tao, Wollscheid, OBrien, Eng, Li, Bodenmiller, Watts, Hood, Aebersold: Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry. dans Nature methods 2005
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Cow (Bovine) Polyclonal G3BP1 Primary Antibody pour WB - ABIN2780221
Kociok, Esser, Unfried, Parker, Schraermeyer, Grisanti, Toqué, Heimann: Upregulation of the RAS-GTPase activating protein (GAP)-binding protein (G3BP) in proliferating RPE cells. dans Journal of cellular biochemistry 1999
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Human Polyclonal G3BP1 Primary Antibody pour IP, PLA - ABIN438758
Fujimura, Sasaki, Anderson: Selenite targets eIF4E-binding protein-1 to inhibit translation initiation and induce the assembly of non-canonical stress granules. dans Nucleic acids research 2012
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Human Polyclonal G3BP1 Primary Antibody pour IF (p), IHC (p) - ABIN801153
Luo, Fang, Jin, Wang, An, Xu, Chen, Xiao: Label-free quantitative phosphoproteomic analysis reveals differentially regulated proteins and pathway in PRRSV-infected pulmonary alveolar macrophages. dans Journal of proteome research 2014
Human Polyclonal G3BP1 Primary Antibody pour IHC - ABIN966169
Beausoleil, Jedrychowski, Schwartz, Elias, Villén, Li, Cohn, Cantley, Gygi: Large-scale characterization of HeLa cell nuclear phosphoproteins. dans Proceedings of the National Academy of Sciences of the United States of America 2004
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Human Polyclonal G3BP1 Primary Antibody pour IF, WB - ABIN523522
Kaehler, Isensee, Nonhoff, Terrey, Hucho, Lehrach, Krobitsch: Ataxin-2-like is a regulator of stress granules and processing bodies. dans PLoS ONE 2012
Human Polyclonal G3BP1 Primary Antibody pour ICC, IF - ABIN4313041
Martin, Bellora, González-Vallinas, Irimia, Chebli, de Toledo, Raabe, Eyras, Urlaub, Blencowe, Tazi: Preferential binding of a stable G3BP ribonucleoprotein complex to intron-retaining transcripts in mouse brain and modulation of their expression in the cerebellum. dans Journal of neurochemistry 2016
Activated glucocorticoid receptor (Montrer NR3C1 Anticorps) induced phosphorylation of v-AKT (Montrer AKT1 Anticorps) Murine Thymoma Viral Oncogene (Montrer RAB1A Anticorps) Homologue (AKT (Montrer AKT1 Anticorps)) kinase, which in turn phosphorylated and promoted nuclear translocation of G3BP1. The nuclear G3BP1 bound to the G3BP1 consensus sequence located on primary miR (Montrer MLXIP Anticorps)-15b~16-2 and miR (Montrer MLXIP Anticorps)-23a~27a~24-2 to inhibit their maturation.
Results show the crystal structure of the NTF2 (Montrer NUTF2 Anticorps)-like domain of G3BP-1 in complex with nsP3 (Montrer SH2D3C Anticorps) protein revealing a poly-complex of G3BP-1 dimers interconnected through the FGDF motifs in nsP3 (Montrer SH2D3C Anticorps). Although in vitro and in vivo binding studies revealed a hierarchical interaction of the two FGDF motifs with G3BP-1, viral growth curves clearly demonstrated that two intact FGDF motifs are required for efficient viral replication.
Based on insights from the structures and existing biochemical data, the existence of an evolutionarily conserved ribonucleoprotein (RNP (Montrer RNPC3 Anticorps)) complex consisting of Caprin-1, FMRP (Montrer FMR1 Anticorps) and G3BP1 is proposed.
G3BP1 interacts directly with the foot-and-mouth disease virus internal ribosome entry site and negatively regulates translation.
The data suggested that JNK (Montrer MAPK8 Anticorps)-enhanced Tudor-SN phosphorylation promotes the interaction between Tudor-SN and G3BP and facilitates the efficient recruitment of Tudor-SN into stress granules under conditions of sodium arsenite-induced oxidative stress.
These data support a role for casein kinase 2 in regulation of protein synthesis by downregulating stress granule formation through G3BP1.
G3BP1 is differentially methylated on specific arginine residues by protein arginine methyltransferase (Montrer PRMT1 Anticorps) (PRMT) 1 (Montrer PRMT1 Anticorps) and PRMT5 (Montrer PRMT5 Anticorps) in its RGG domain.
Our data define G3BP1 as a novel independent prognostic factor that is correlated with gastric cancer progression.
G3BP mediates the condensation of stress granules by shifting between two different states that are controlled by the phosphorylation of S149 and by binding to Caprin1 or USP10 (Montrer USP10 Anticorps).
Host G3BP1 captures HIV-1 RNA transcripts and thereby restricts mRNA translation, viral protein production and virus particle formation.
the aberrant mutant SOD1 (Montrer SOD1 Anticorps)-G3BP1 interaction affects stress granule dynamics
G3BP is involved in a new functional mechanism to regulate non-coding RNAs including intron-retaining transcripts, and thus have broad implications for neuronal gene regulation, where intron retention is widespread
G3bp1 posttranscriptionally regulates miRNA-1 processing in the heart.
Our findings identified a novel function of G3BP1 in the progression of breast cancer via activation of the epithelial-to-mesenchymal transition
Cytoplasmic granule containing HERMES (Montrer CD44 Anticorps), NonO (Montrer NONO Anticorps), PSF (Montrer IL-3 Anticorps), and G3BP1 is a neuronal RNA-protein granule that is transported in neurites during retinal differentiation.
These results show, for the first time, a requirement for G3BP1 in the control of neuronal plasticity and calcium homeostasis
Data show that protein kinase (Montrer CDK7 Anticorps) R as the principal kinase that mediates eukaryotic initiation factor 2alpha (eIF2alpha (Montrer EIF2S1 Anticorps)) phosphorylation by large RasGAP (Montrer RASA1 Anticorps) SH3-binding protein (Montrer SH3BP5 Anticorps) (G3BP)-induced granules.
arguments against G3BP1 being a genuine RasGAP (Montrer RASA1 Anticorps)-binding partner
G3BP1 is a novel Ctnnb1 (Montrer CTNNB1 Anticorps) mRNA binding protein. Methylation of G3BP1 constitutes a molecular switch that regulates Ctnnb1 (Montrer CTNNB1 Anticorps) mRNA in response to Wnt3a (Montrer WNT3A Anticorps).
IMP-1 (Montrer IMPA1 Anticorps) associates with HuD (Montrer ELAVL4 Anticorps) and G3BP-1 proteins in an RNA-dependent manner and binds directly to tau mRNA. We also show an RNA-dependent association between G3BP-1 and HuD (Montrer ELAVL4 Anticorps) proteins
It has been demonstrated a depletion of G3BP1 and TIA-1/TIAR in senescent cells and it was shown that the loss of G3BP1 contributed to impaired stress granules formation.
This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
ATP-dependent DNA helicase VIII
, GAP SH3 domain-binding protein 1
, GAP binding protein
, Ras-GTPase-activating protein SH3-domain-binding protein
, RasGAP-associated endoribonuclease G3BP
, ras GTPase-activating protein-binding protein 1
, GTPase activating protein (SH3 domain) binding protein 1
, ATP-dependent DNA/RNA helicase G3BP
, Ras-GTPase-activating protein SH3-domain binding protein 1
, GAP SH3 binding protein