anti-GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1) Anticorps

G3BP1 encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. De plus, nous expédions GTPase Activating Protein (SH3 Domain) Binding Protein 1 Protéines (12) et GTPase Activating Protein (SH3 Domain) Binding Protein 1 Kits (9) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
G3BP1 10146 Q13283
G3BP1 171092  
G3BP1 27041 P97855
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Top anti-GTPase Activating Protein (SH3 Domain) Binding Protein 1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 155 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, IP, WB WB Suggested Anti-G3BP1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  HT1080 cell lysate G3BP1 is strongly supported by BioGPS gene expression data to be expressed in Human HT1080 cells IP Suggested Anti-G3BP1 Antibody Positive Control: NT2 CELL/BRAIN TISSUE 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Souris Inconjugué IF, IHC, WB Immunofluorescence of monoclonal antibody to G3BP on HeLa cell (antibody concentration 10 µg/mL). Western blot analysis of G3BP over-expressed 293 cell line, cotransfected with G3BP Validated Chimera RNAi used as specificity and loading control. 100 μg Connectez-vous pour afficher 8 to 11 Days
$527.50
Détails
Boeuf (Vache) Lapin Inconjugué WB Host:  Rabbit  Target Name:  G3BP  Sample Type:  HepG2  Lane A:  Primary Antibody  Lane B:  Primary Antibody + Blocking Peptide  Primary Antibody Concentration:  2.5ug/mL  Peptide Concentration:  2.0ug/mL  Lysate Quantity:  25ug/lane  Gel Concentration:  12% WB Suggested Anti-G3BP Antibody Titration:  2.5ug/ml  ELISA Titer:  1:312500  Positive Control:  HepG2 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$249.00
Détails
Humain Lapin Inconjugué IHC (p), WB G3BP1 Antibody (C-term) (ABIN657707) western blot analysis in Jurkat cell line lysates (35 µg/lane). This demonstrates the G3BP1 antibody detected the G3BP1 protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$385.00
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Western Blot: G3BP1 Antibody [NBP1-83404] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells).Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells) Immunocytochemistry/Immunofluorescence: G3BP1 Antibody [NBP1-83404] - Staining of human cell line U-251MG shows positivity in cytoplasm. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$494.38
Détails
Humain Lapin Inconjugué IC, IF, IHC, WB Immunofluorescent analysis of G3BP1 staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of G3BP1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué IC, IF, IHC, WB Immunofluorescent analysis of G3BP1 (pS232) staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of G3BP1 (pS232) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Connectez-vous pour afficher 13 to 14 Days
$575.00
Détails
Humain Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 2 to 3 Days
$275.00
Détails
Boeuf (Vache) Lapin Inconjugué WB Host:  Rabbit  Target Name:  G3BP1  Sample Type:  Pancreas tumor lysates  Antibody Dilution:  1.0ug/ml 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué IHC, ELISA, WB Western blot analysis of extracts from HeLa cells, using G3BP-1 (Ab-232) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using G3BP-1 (Ab-232) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails

anti-GTPase Activating Protein (SH3 Domain) Binding Protein 1 Anticorps mieux référencés

  1. Human Monoclonal G3BP1 Primary Antibody pour IF, IHC (p) - ABIN564390 : Norazit, Meedeniya, Nguyen, Mackay-Sim: Progressive loss of dopaminergic neurons induced by unilateral rotenone infusion into the medial forebrain bundle. dans Brain research 2010 (PubMed)
    Show all 4 Pubmed References

  2. Human G3BP1 Primary Antibody pour IHC - ABIN966168 : Tao, Wollscheid, OBrien, Eng, Li, Bodenmiller, Watts, Hood, Aebersold: Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry. dans Nature methods 2005 (PubMed)
    Show all 5 Pubmed References

  3. Human Polyclonal G3BP1 Primary Antibody pour IP, PLA - ABIN438758 : Fujimura, Sasaki, Anderson: Selenite targets eIF4E-binding protein-1 to inhibit translation initiation and induce the assembly of non-canonical stress granules. dans Nucleic acids research 2012 (PubMed)
    Show all 2 Pubmed References

  4. Cow (Bovine) Polyclonal G3BP1 Primary Antibody pour WB - ABIN2780221 : Kociok, Esser, Unfried, Parker, Schraermeyer, Grisanti, Toqué, Heimann: Upregulation of the RAS-GTPase activating protein (GAP)-binding protein (G3BP) in proliferating RPE cells. dans Journal of cellular biochemistry 1999 (PubMed)
    Show all 3 Pubmed References

  5. Human Polyclonal G3BP1 Primary Antibody pour IF, WB - ABIN6140859 : Hu, Wang, Tang, Yang, Qin, Chen: Inclusion bodies of human parainfluenza virus type 3 inhibit antiviral stress granule formation by shielding viral RNAs. dans PLoS pathogens 2018 (PubMed)
    Show all 2 Pubmed References

  6. Human Polyclonal G3BP1 Primary Antibody pour IF, WB - ABIN6680469 : Ye, Pan, Wang, Fang, Ma, Zhu, Shi, Zhang, Zheng, Chen, Li, Xiao: Foot-and-Mouth Disease Virus Counteracts on Internal Ribosome Entry Site Suppression by G3BP1 and Inhibits G3BP1-Mediated Stress Granule Assembly via Post-Translational Mechanisms. dans Frontiers in immunology 2018 (PubMed)
    Show all 2 Pubmed References

  7. Human Polyclonal G3BP1 Primary Antibody pour IF (p), IHC (p) - ABIN801153 : Luo, Fang, Jin, Wang, An, Xu, Chen, Xiao: Label-free quantitative phosphoproteomic analysis reveals differentially regulated proteins and pathway in PRRSV-infected pulmonary alveolar macrophages. dans Journal of proteome research 2014 (PubMed)

  8. Human Polyclonal G3BP1 Primary Antibody pour IHC - ABIN966169 : Beausoleil, Jedrychowski, Schwartz, Elias, Villén, Li, Cohn, Cantley, Gygi: Large-scale characterization of HeLa cell nuclear phosphoproteins. dans Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)
    Show all 3 Pubmed References

  9. Human Polyclonal G3BP1 Primary Antibody pour IF, WB - ABIN523522 : Kaehler, Isensee, Nonhoff, Terrey, Hucho, Lehrach, Krobitsch: Ataxin-2-like is a regulator of stress granules and processing bodies. dans PLoS ONE 2012 (PubMed)

  10. Human Polyclonal G3BP1 Primary Antibody pour ICC, IF - ABIN4313041 : Martin, Bellora, González-Vallinas, Irimia, Chebli, de Toledo, Raabe, Eyras, Urlaub, Blencowe, Tazi: Preferential binding of a stable G3BP ribonucleoprotein complex to intron-retaining transcripts in mouse brain and modulation of their expression in the cerebellum. dans Journal of neurochemistry 2016 (PubMed)

Plus d’anticorps contre GTPase Activating Protein (SH3 Domain) Binding Protein 1 partenaires d’interaction

Human GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1) interaction partners

  1. High G3BP1expression is associated with arteriosclerosis.

  2. The disruption of stress granules (SGs) during the late stage of Enterovirus 71 (EV71) infection is caused by viral protease 3C-mediated cleavage of G3BP stress granule assembly factor 1 (G3BP1). Over-expression of G3BP1-SGs negatively impacts viral replication at the cytopathic effect (CPE), protein, RNA, and viral titer levels.

  3. JMJD6 is a novel Stress Granule component that interacts with G3BP1 complexes, and its expression reduces G3BP1 monomethylation and asymmetric dimethylation at three Arg residues.

  4. Activated glucocorticoid receptor induced phosphorylation of v-AKT Murine Thymoma Viral Oncogene Homologue (AKT) kinase, which in turn phosphorylated and promoted nuclear translocation of G3BP1. The nuclear G3BP1 bound to the G3BP1 consensus sequence located on primary miR-15b~16-2 and miR-23a~27a~24-2 to inhibit their maturation.

  5. Results show the crystal structure of the NTF2-like domain of G3BP-1 in complex with nsP3 protein revealing a poly-complex of G3BP-1 dimers interconnected through the FGDF motifs in nsP3. Although in vitro and in vivo binding studies revealed a hierarchical interaction of the two FGDF motifs with G3BP-1, viral growth curves clearly demonstrated that two intact FGDF motifs are required for efficient viral replication.

  6. Based on insights from the structures and existing biochemical data, the existence of an evolutionarily conserved ribonucleoprotein (RNP) complex consisting of Caprin-1, FMRP and G3BP1 is proposed.

  7. G3BP1 interacts directly with the foot-and-mouth disease virus internal ribosome entry site and negatively regulates translation.

  8. The data suggested that JNK-enhanced Tudor-SN phosphorylation promotes the interaction between Tudor-SN and G3BP and facilitates the efficient recruitment of Tudor-SN into stress granules under conditions of sodium arsenite-induced oxidative stress.

  9. These data support a role for casein kinase 2 in regulation of protein synthesis by downregulating stress granule formation through G3BP1.

  10. G3BP1 is differentially methylated on specific arginine residues by protein arginine methyltransferase (PRMT) 1 and PRMT5 in its RGG domain.

  11. Our data define G3BP1 as a novel independent prognostic factor that is correlated with gastric cancer progression.

  12. G3BP mediates the condensation of stress granules by shifting between two different states that are controlled by the phosphorylation of S149 and by binding to Caprin1 or USP10.

  13. Host G3BP1 captures HIV-1 RNA transcripts and thereby restricts mRNA translation, viral protein production and virus particle formation.

  14. Our findings identified a novel function of G3BP1 in the progression of breast cancer via activation of the epithelial-to-mesenchymal transition

  15. G3BP1 granules were assembled independently of TIA-1 and had a negative impact on Dengue virus replication.

  16. The G3BP1-Caprin1-PKR complex represents a new mode of PKR activation and is important for antiviral activity of G3BP1 and PKR during infection with mengovirus.

  17. In this report, we demonstrate that a novel peptide GAP161 blocked the functions of G3BP and markedly suppressed HCT116 cell growth through the induction of apoptosis

  18. eQTLs acting across multiple tissues are significant carriers of inherited risk for CAD. FLYWCH1, PSORSIC3, and G3BP1 are novel master regulatory genes in CAD that may be suitable targets.

  19. ICP8 binding to G3BP also inhibits SG formation, which is a novel function of HSV ICP8.

  20. G3BP1 has a role in modulating stress granule assembly during HIV-1 infection

Mouse (Murine) GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1) interaction partners

  1. the aberrant mutant SOD1-G3BP1 interaction affects stress granule dynamics

  2. G3BP is involved in a new functional mechanism to regulate non-coding RNAs including intron-retaining transcripts, and thus have broad implications for neuronal gene regulation, where intron retention is widespread

  3. G3bp1 posttranscriptionally regulates miRNA-1 processing in the heart.

  4. Our findings identified a novel function of G3BP1 in the progression of breast cancer via activation of the epithelial-to-mesenchymal transition

  5. Cytoplasmic granule containing HERMES, NonO, PSF, and G3BP1 is a neuronal RNA-protein granule that is transported in neurites during retinal differentiation.

  6. These results show, for the first time, a requirement for G3BP1 in the control of neuronal plasticity and calcium homeostasis

  7. Data show that protein kinase R as the principal kinase that mediates eukaryotic initiation factor 2alpha (eIF2alpha) phosphorylation by large RasGAP SH3-binding protein (G3BP)-induced granules.

  8. arguments against G3BP1 being a genuine RasGAP-binding partner

  9. G3BP1 is a novel Ctnnb1 mRNA binding protein. Methylation of G3BP1 constitutes a molecular switch that regulates Ctnnb1 mRNA in response to Wnt3a.

  10. IMP-1 associates with HuD and G3BP-1 proteins in an RNA-dependent manner and binds directly to tau mRNA. We also show an RNA-dependent association between G3BP-1 and HuD proteins

  11. the physical interaction between RasGAP and FLN-C facilitates an interaction between G3BP and cdk7 mRNA

  12. G3BP is essential for proper embryonic growth and development by mediating the coordinate expression of multiple imprinted growth-regulatory transcripts

Pig (Porcine) GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1) interaction partners

  1. It has been demonstrated a depletion of G3BP1 and TIA-1/TIAR in senescent cells and it was shown that the loss of G3BP1 contributed to impaired stress granules formation.

GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1) profil antigène

Profil protéine

This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Gene names and symbols associated with G3BP1

  • G3BP stress granule assembly factor 1 (G3BP1) anticorps
  • GTPase activating protein (SH3 domain) binding protein 1 (g3bp1) anticorps
  • GTPase activating protein (SH3 domain) binding protein 1 L homeolog (g3bp1.L) anticorps
  • Ras-GTPase-activating protein SH3-domain-binding protein (LOC100304885) anticorps
  • G3BP stress granule assembly factor 1 (G3bp1) anticorps
  • GTPase activating protein (SH3 domain) binding protein 1 (G3bp1) anticorps
  • AI849976 anticorps
  • B430204O07 anticorps
  • C87777 anticorps
  • fj17h05 anticorps
  • G3bp anticorps
  • G3BP1 anticorps
  • HDH-VIII anticorps
  • MGC53271 anticorps
  • mKIAA4115 anticorps
  • RGD1310666 anticorps
  • wu:fj17h05 anticorps
  • zgc:56034 anticorps

Protein level used designations for G3BP1

ATP-dependent DNA helicase VIII , G3BP-1 , GAP SH3 domain-binding protein 1 , GAP binding protein , Ras-GTPase-activating protein SH3-domain-binding protein , RasGAP-associated endoribonuclease G3BP , ras GTPase-activating protein-binding protein 1 , GTPase activating protein (SH3 domain) binding protein 1 , ATP-dependent DNA/RNA helicase G3BP , Ras-GTPase-activating protein SH3-domain binding protein 1 , GAP SH3 binding protein , HDH-VIII

GENE ID SPECIES
10146 Homo sapiens
335512 Danio rerio
380390 Xenopus laevis
471711 Pan troglodytes
534214 Bos taurus
713884 Macaca mulatta
100304885 Ictalurus punctatus
171092 Rattus norvegicus
27041 Mus musculus
479322 Canis lupus familiaris
100513766 Sus scrofa
100172476 Pongo abelii
100725714 Cavia porcellus
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