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anti-Genome Polyprotein Anticorps

17 Résultats:

anti-Genome Polyprotein (LOC100493440) (AA 575-866) anticorps Primary Antibody

LOC100493440 Reactivité: Human Rhinovirus A (HRV-A) ELISA, WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2754748
$328.90
Plus shipping costs $45.00
100 μg (More quantities available)
local_shipping Destination: Etats-Unis
Envoi sous 10 à 13 jours ouvrables

anti-Genome Polyprotein (LOC100493440) (AA 575-866) anticorps (HRP) Primary Antibody

LOC100493440 Reactivité: Human Rhinovirus A (HRV-A) ELISA, WB Hôte: Lapin Polyclonal HRP
N° du produit ABIN2754749
$328.90
Plus shipping costs $45.00
100 μg (More quantities available)
local_shipping Destination: Etats-Unis
Envoi sous 10 à 13 jours ouvrables

anti-Genome Polyprotein (LOC100493440) (AA 575-866) anticorps (FITC) Primary Antibody

LOC100493440 Reactivité: Human Rhinovirus A (HRV-A) ELISA, WB Hôte: Lapin Polyclonal FITC
N° du produit ABIN2754750
$328.90
Plus shipping costs $45.00
100 μg (More quantities available)
local_shipping Destination: Etats-Unis
Envoi sous 10 à 13 jours ouvrables

anti-Genome Polyprotein (LOC100493440) (AA 575-866) anticorps (Biotin) Primary Antibody

LOC100493440 Reactivité: Human Rhinovirus A (HRV-A) ELISA, WB Hôte: Lapin Polyclonal Biotin
N° du produit ABIN2754751
$328.90
Plus shipping costs $45.00
100 μg (More quantities available)
local_shipping Destination: Etats-Unis
Envoi sous 10 à 13 jours ouvrables

anti-Genome Polyprotein (LOC100493440) anticorps Primary Antibody

LOC100493440 Reactivité: Dengue Virus ELISA, WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2754511
$328.90
Plus shipping costs $45.00
100 μg (More quantities available)
local_shipping Destination: Etats-Unis
Envoi sous 10 à 13 jours ouvrables

anti-Genome Polyprotein (LOC100493440) anticorps (HRP) Primary Antibody

LOC100493440 Reactivité: Dengue Virus ELISA, WB Hôte: Lapin Polyclonal HRP
N° du produit ABIN2754512
$328.90
Plus shipping costs $45.00
100 μg (More quantities available)
local_shipping Destination: Etats-Unis
Envoi sous 10 à 13 jours ouvrables

anti-Genome Polyprotein (LOC100493440) anticorps (FITC) Primary Antibody

LOC100493440 Reactivité: Dengue Virus ELISA, WB Hôte: Lapin Polyclonal FITC
N° du produit ABIN2754513
$328.90
Plus shipping costs $45.00
100 μg (More quantities available)
local_shipping Destination: Etats-Unis
Envoi sous 10 à 13 jours ouvrables

anti-Genome Polyprotein (LOC100493440) anticorps (Biotin) Primary Antibody

LOC100493440 Reactivité: Dengue Virus ELISA, WB Hôte: Lapin Polyclonal Biotin
N° du produit ABIN2754514
$328.90
Plus shipping costs $45.00
100 μg (More quantities available)
local_shipping Destination: Etats-Unis
Envoi sous 10 à 13 jours ouvrables

anti-Genome Polyprotein (LOC100493440) (AA 575-866) anticorps (Biotin) Primary Antibody

LOC100493440 Reactivité: Virus ELISA Hôte: Lapin Polyclonal Biotin
N° du produit ABIN2930558
$435.60
Plus shipping costs $45.00
100 μg (More quantities available)
local_shipping Destination: Etats-Unis
Envoi sous 11 à 16 jours ouvrables

anti-Genome Polyprotein (LOC100493440) anticorps (Biotin) Primary Antibody

LOC100493440 Reactivité: Virus ELISA Hôte: Lapin Polyclonal Biotin
N° du produit ABIN2930559
$435.60
Plus shipping costs $45.00
100 μg (More quantities available)
local_shipping Destination: Etats-Unis
Envoi sous 11 à 16 jours ouvrables
  • Type Primary
    • Primary
  • Target Genome Polyprotein (LOC100493440)
    • Genome Polyprotein (LOC100493440)
    • Histone 3 (H3)
    • Tumor Protein P53 (TP53)
    • Epidermal Growth Factor Receptor (EGFR)
    • Mast/stem Cell Growth Factor Receptor (KIT)
    • Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
    • CD4
    • tau Protein
    • Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2)
    • Tumor Necrosis Factor alpha (TNF alpha)
    • V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1)
    • Interferon gamma (IFNG)
    • Nuclear Factor-kB p65 (NFkBP65)
    • Estrogen Receptor 1 (ESR1)
    • Albumin (ALB)
    • BCL2-Associated Agonist of Cell Death (BAD)
    • B-Cell CLL/lymphoma 2 (BCL2)
    • V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
    • CD8a Molecule (CD8A)
    • Platelet/endothelial Cell Adhesion Molecule (PECAM1)
    • Tuberous Sclerosis 2 (TSC2)
    • CD19 Molecule (CD19)
    • CD3 epsilon (CD3E)
    • Hemagglutinin (HA)
    • Integrin alpha M (ITGAM)
    • CD8
    • Histone H4
    • CD44
    • Jun Proto-Oncogene (JUN)
    • Interleukin 6 (IL6)
    • Epithelial Cell Adhesion Molecule (EPCAM)
    • Myc Proto-Oncogene protein (MYC)
    • Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1)
    • Interleukin 2 Receptor, alpha (IL2RA)
    • Catenin, beta
    • CD5 Molecule (CD5)
    • Vimentin (VIM)
    • Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1)
    • Mucin 1, Cell Surface Associated (MUC1)
    • CD3
    • PTK2 Protein tyrosine Kinase 2 (PTK2)
    • Glial Fibrillary Acidic Protein (GFAP)
    • C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
    • CD34
    • Interleukin 2 (IL2)
    • Insulin Receptor Substrate 1 (IRS1)
    • Keratin 18 (KRT18)
    • Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR)
    • Amyloid beta (A4) Precursor Protein (APP)
    • CD14
    • Tuberous Sclerosis 1 (TSC1)
  • Application
    • ELISA
    • Western Blotting (WB)
  • Réactivité
    • Virus
    • Dengue Virus
    • Human Rhinovirus A (HRV-A)
  • Hote
    • Lapin
  • Clonalité
    • Polyclonal
  • Epitope
    • AA 575-866
    • AA 192-325
  • Conjugué
    • Inconjugué
    • Biotin
    • FITC
    • HRP
  • Isotype
    • IgG
  • Format
    • Liquid

Genome Polyprotein (LOC100493440) profil antigène

Profil protéine

Capsid protein C: Plays a role in virus budding by binding to the cell membrane and gathering the viral RNA into a nucleocapsid that forms the core of a mature virus particle. During virus entry, may induce genome penetration into the host cytoplasm after hemifusion induced by the surface proteins. Can migrate to the cell nucleus where it modulates host functions. {ECO:0000250|UniProtKB:P17763}. Capsid protein C: Inhibits RNA silencing by interfering with host Dicer. {ECO:0000269|PubMed:27849599}. Peptide pr: Prevents premature fusion activity of envelope proteins in trans-Golgi by binding to envelope protein E at pH6.0. After virion release in extracellular space, gets dissociated from E dimers. {ECO:0000250|UniProtKB:P17763}. Protein prM: Acts as a chaperone for envelope protein E during intracellular virion assembly by masking and inactivating envelope protein E fusion peptide. prM is the only viral peptide matured by host furin in the trans-Golgi network probably to avoid catastrophic activation of the viral fusion activity in acidic Golgi compartment prior to virion release. prM-E cleavage is inefficient, and many virions are only partially matured. These uncleaved prM would play a role in immune evasion. {ECO:0000250|UniProtKB:P17763}. Small envelope protein M: May play a role in virus budding. Exerts cytotoxic effects by activating a mitochondrial apoptotic pathway through M ectodomain. May display a viroporin activity. {ECO:0000250|UniProtKB:P17763}. Envelope protein E: Binds to host cell surface receptor and mediates fusion between viral and cellular membranes. Envelope protein is synthesized in the endoplasmic reticulum in the form of heterodimer with protein prM. They play a role in virion budding in the ER, and the newly formed immature particule is covered with 60 spikes composed of heterodimer between precursor prM and envelope protein E. The virion is transported to the Golgi apparatus where the low pH causes dissociation of PrM-E heterodimers and formation of E homodimers. prM-E cleavage is inefficient, and many virions are only partially matured. These uncleaved prM would play a role in immune evasion. {ECO:0000250|UniProtKB:P17763}. Non-structural protein 1: Involved in immune evasion, pathogenesis and viral replication. Once cleaved off the replication cycle, the plasma membrane and the extracellular compartment. Essential for viral replication. Required for formation of the replication complex and recruitment of other non- structural proteins to the ER-derived membrane structures. Excreted as a hexameric lipoparticle that plays a role against host immune response. Antagonizing the complement function. Binds to the host macrophages and dendritic cells. Inhibits signal transduction originating from Toll-like receptor 3 (TLR3). {ECO:0000250|UniProtKB:Q9Q6P4, ECO:0000269|PubMed:9371625}. Non-structural protein 2A: Component of the viral RNA replication complex that functions in virion assembly and antagonizes the host immune response. {ECO:0000250|UniProtKB:P17763}. Serine protease subunit NS2B: Required cofactor for the serine protease function of NS3. May have membrane-destabilizing activity and form viroporins (By similarity). {ECO:0000250|UniProtKB:P17763, ECO:0000255|PROSITE- ProRule:PRU00859}. Serine protease NS3: Displays three enzymatic protease, in association with NS2B, performs its autocleavage and NS2A-NS2B, NS2B-NS3, NS3-NS4A, NS4A-2K and NS4B-NS5. NS3 RNA helicase binds RNA and unwinds dsRNA in the 3' to 5' direction. Also plays a role in virus assembly (PubMed:18199634). {ECO:0000255|PROSITE-ProRule:PRU00860, ECO:0000269|PubMed:18199634}. Non-structural protein 4A: Regulates the ATPase activity of the NS3 helicase activity. NS4A allows NS3 helicase to conserve energy during unwinding. {ECO:0000250|UniProtKB:Q9Q6P4}. Peptide 2k: Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter. {ECO:0000250|UniProtKB:P17763}. Non-structural protein 4B: Induces the formation of ER- derived membrane vesicles where the viral replication takes place. Inhibits interferon (IFN)-induced host STAT1 phosphorylation and nuclear translocation, thereby preventing the establishment of cellular antiviral state by blocking the IFN-alpha/beta pathway (PubMed:15956546). {ECO:0000250|UniProtKB:Q9Q6P4, ECO:0000269|PubMed:15956546}. RNA-directed RNA polymerase NS5: Replicates the viral (+) and (-) RNA genome, and performs the capping of genomes in the cytoplasm (PubMed:19850911). NS5 methylates viral RNA cap at guanine N-7 and ribose 2'-O positions (PubMed:19850911). Besides its role in RNA genome replication, also prevents the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) signaling pathway (PubMed:25211074). IFN-I induces binding of NS5 to host IFN- activated transcription factor STAT2, preventing its transcriptional activity. Host TRIM23 is the E3 ligase that interacts with and polyubiquitinates NS5 to promote its binding to STAT2 and trigger IFN-I signaling inhibition (PubMed:25211074). {ECO:0000269|PubMed:19850911, ECO:0000269|PubMed:25211074}.

Gene names and symbols associated with LOC100493440

  • polyprotein precursor (YFVgp1) anticorps
GENE ID SPECIES
1502173 Yellow fever virus

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