anti-Inositol-Trisphosphate 3-Kinase B (ITPKB) Anticorps

The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4.

afficher tous les anticorps Gène GeneID UniProt
Anti-Souris ITPKB ITPKB 320404  
Anti-Humain ITPKB ITPKB 3707 P27987
Anti-Rat ITPKB ITPKB 54260 P42335
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Top anti-ITPKB Anticorps sur anticorps-enligne.fr

Showing 10 out of 53 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué WB Western blot analysis of ITPKB expression in HeLa (A), SP2/0 (B), H9C2 (C) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué WB Western blot analysis of extracts of various cells, using ITPKB antibody. Immunohistochemistry of paraffin-embedded human liver injury using ITPKB antibody at dilution of 1:100 (x40 lens). 100 μL Connectez-vous pour afficher 16 Days
$476.15
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB Immunohistochemistry: ITPKB Antibody [NBP1-81589] - Staining of human lung shows moderate cytoplasmic positivity in alveolar cells. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$491.63
Détails
Humain Souris Inconjugué ELISA, WB ITPKB monoclonal antibody (M01), clone 2F8 Western Blot analysis of ITPKB expression in Jurkat . Western Blot analysis of ITPKB expression in transfected 293T cell line by ITPKB monoclonal antibody (M01), clone 2F8.<br><br>Lane 1: ITPKB transfected lysate(67.4 KDa).<br>Lane 2: Non-transfected lysate.<br> 100 μg Connectez-vous pour afficher 11 to 12 Days
$440.00
Détails
Humain Lapin Inconjugué FACS, IHC (p), WB Western blot analysis of ITPKB (arrow) using rabbit polyclonal ITPKB Antibody (R38) (ABIN652430). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the ITPKB gene. ITPKB Antibody (N-term) (ABIN652430)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails
Humain Souris Inconjugué WB Western Blot analysis of ITPKB expression in transfected 293T cell line by ITPKB monoclonal antibody (M01), clone 2F8. Lane 1: ITPKB transfected lysate(67.4 KDa). Lane 2: Non-transfected lysate. ITPKB monoclonal antibody (M01), clone 2F8 Western Blot analysis of ITPKB expression in Jurkat. 0.1 mg Connectez-vous pour afficher 8 to 11 Days
$450.00
Détails
Humain Souris Inconjugué ELISA, WB   100 μg Connectez-vous pour afficher 7 to 9 Days
$537.17
Détails
Humain Lapin Inconjugué IHC, ELISA   100 μL Connectez-vous pour afficher 7 to 9 Days
$390.50
Détails
Humain Lapin Inconjugué WB   100 μL Connectez-vous pour afficher 2 to 3 Days
$376.44
Détails
Humain Lapin Inconjugué WB   100 μL Connectez-vous pour afficher 7 to 9 Days
$375.83
Détails

anti-ITPKB Anticorps mieux référencés

  1. Human Monoclonal ITPKB Primary Antibody pour ELISA, WB - ABIN561565 : Nalaskowski, Fliegert, Ernst, Brehm, Fanick, Windhorst, Lin, Giehler, Hein, Lin, Mayr: Human inositol 1,4,5-trisphosphate 3-kinase isoform B (IP3KB) is a nucleocytoplasmic shuttling protein specifically enriched at cortical actin filaments and at invaginations of the nuclear envelope. dans The Journal of biological chemistry 2011 (PubMed)

  2. Human Polyclonal ITPKB Primary Antibody pour IHC, IHC (p) - ABIN4327792 : Jin, Liu, Zhang, Huang, Jiang, Hou, Xu, Zhai, Gao, Wang, Wu, Zhu, Lu: The Expression of miR-375 Is Associated with Carcinogenesis in Three Subtypes of Lung Cancer. dans PLoS ONE 2015 (PubMed)

Plus d’anticorps contre ITPKB partenaires d’interaction

Mouse (Murine) Inositol-Trisphosphate 3-Kinase B (ITPKB) interaction partners

  1. Thus, non-canonical phosphoinositide 3-kinase-antagonism by Itpkb restricts pre-T cell receptor (Montrer PTCRA Anticorps) induced metabolic activation to enforce coincidence-detection of pre-T cell receptor (Montrer PTCRA Anticorps) expression and Notch (Montrer NOTCH1 Anticorps)-engagement.

  2. These data identify Itpkb as an essential mediator of T cell activation and suggest Itpkb inhibition as a novel approach to treat autoimmune disease.

  3. Itpkb controls hematopoietic stem cell homeostasis and prevent death from severe anemia in mice.

  4. Itpkb controls survival, proliferation and cytokine production in mouse peripheral T cells.

  5. Data present the structure of the complete catalytic domain of inositol 1,4,5-trisphophate 3-kinase B, including the CaM binding domain in complex with Mg(2 (Montrer MCOLN1 Anticorps)+) and ATP.

  6. These data show that the absence of expression of the three isoenzymes of Itpk does not prevent the formation of IP5 and IP6 (Montrer GPRIN2 Anticorps), at least in mouse embryonic fibroblasts.[Itpka (Montrer ITPKA Anticorps), Itpkb, Itpkc (Montrer ITPKC Anticorps)]

  7. Itpkb and inositol tetrakisphosphate mediate a survival signal in B cells.

  8. B cells from Itpkb(-/-) Ig hen (Montrer RPS6 Anticorps) egg lysozyme (Montrer LYZ Anticorps) mice possess an anergic phenotype, hypoproliferate in response to cognate Ag, and yet they exhibit enhanced Ag-induced calcium signaling

Human Inositol-Trisphosphate 3-Kinase B (ITPKB) interaction partners

  1. miR (Montrer MLXIP Anticorps)-140-5p regulates this context-specific autophagy through its target, inositol 1,4,5-trisphosphate kinase 2 (IP3k2). Therefore, the results of the present study demonstrated that miR (Montrer MLXIP Anticorps)-140-5p mediated drug-resistance in osteosarcoma cells by inducing autophagy.

  2. The authors confirm downregulation of miR (Montrer MLXIP Anticorps)-132 and upregulation of ITPKB in three distinct human Alzheimer's disease patient cohorts.

  3. ITPKB is increased in Alzheimer's brain three-fold in the cerebral cortex of most patients with Alzheimer's disease compared with control subjects and accumulates in dystrophic neurites associated with amyloid plaques.

  4. a specific increase in inositol 1,4,5-trisphosphate 3-kinase A (Montrer ITPKA Anticorps) and B (ITPKA (Montrer ITPKA Anticorps) and ITPKB) was observed upon hESCs spontaneous differentiation.

  5. IP3KB not only regulates cytoplasmic Ca(2 (Montrer CA2 Anticorps)+) signals by phosphorylation of subplasmalemmal and cytoplasmic Ins (Montrer INS Anticorps)(1,4,5)P(3) but may also be involved in modulating nuclear Ca(2 (Montrer CA2 Anticorps)+) signals generated from these nuclear envelope invaginations.

  6. results highlight the potential role of the three isoforms of InsP3 3-kinase as direct InsP3 metabolizing enzymes and direct regulators of Ca2 (Montrer CA2 Anticorps)+ responses to extracellular signals

  7. We aim to summarize the existing information about functionally uncoupled IP(3)R (Montrer ITPR1 Anticorps) and RyR (Montrer RYR1 Anticorps) channels, and to discuss the concept that those channels can participate in Ca(2 (Montrer CA2 Anticorps)+)-leak pathways.

  8. In each of the three isoforms a nuclear export signal has evolved in the catalytic domain either de novo (IP3K-A (Montrer ITPKA Anticorps)) or as a substitute for an earlier evolved corresponding N-terminal signal (IP3K-B and IP3K-C (Montrer ITPKC Anticorps)).

ITPKB profil antigène

Profil protéine

The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity.

Gene names and symbols associated with ITPKB

  • inositol 1,4,5-trisphosphate 3-kinase B (Itpkb) anticorps
  • inositol-trisphosphate 3-kinase B (ITPKB) anticorps
  • inositol-trisphosphate 3-kinase B (itpkb) anticorps
  • inositol-trisphosphate 3-kinase B (LOC698185) anticorps
  • inositol-trisphosphate 3-kinase B (Itpkb) anticorps
  • 1110033J02Rik anticorps
  • E130307H12Rik anticorps
  • IP3-3KB anticorps
  • IP3K anticorps
  • IP3K-B anticorps
  • IP3KB anticorps
  • PIG37 anticorps
  • si:ch211-97m8.1 anticorps

Protein level used designations for ITPKB

inositol-trisphosphate 3-kinase B , inositol 1,4,5-trisphosphate 3-kinase B , 1D-myo-inositol-trisphosphate 3-kinase B , inositol-trisphosphate 3-kinase B-like , IP3 3-kinase B , IP3K B , insP 3-kinase B , proliferation-inducing protein 37 , IP3K-B

GENE ID SPECIES
320404 Mus musculus
416743 Gallus gallus
457789 Pan troglodytes
490383 Canis lupus familiaris
540877 Bos taurus
563019 Danio rerio
698185 Macaca mulatta
100400613 Callithrix jacchus
100460190 Pongo abelii
100603824 Nomascus leucogenys
3707 Homo sapiens
54260 Rattus norvegicus
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