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May be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. De plus, nous expédions Lectin, Mannose-Binding 2-Like Protéines (10) et beaucoup plus de produits pour cette protéine.
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Homozygous missense mutation p.R53Q in the LMAN2L gene causes autosomal recessive intellectual disability and seizures.
Study showed a significant association between LMAN2L and risk of both bipolar disorder and schizophrenia
The results of this study suggested that significant novel association signals near the genes LMAN2L and provide supportive evidence for the previously reported association signals near ANK3 and within the 3p21.1 locus.
VIPL terminates in the sequence KRFY, characteristic for proteins recycling between the ER and ERGIC/cis-Golgi; and knock-down of VIPL mRNA slowed secretion of two glycoproteins (35 and 250 kDa), suggesting that VIPL may function as an ER export receptor.
selective interaction of VIPL and VIP36 with the deglucosylated trimannose in the D1 branch of high-mannose-type oligosaccharides but with different pH dependence.
May be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. May function as a regulator of ERGIC-53 (By similarity).
, VIP36-like protein
, lectin mannose-binding 2-like
, vesicular integral-membrane protein VIP36-like protein