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LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor (NR) box (Fernandes et al., 2003 [PubMed 12535528]).[supplied by OMIM, Mar 2008].. De plus, nous expédions Lcor Protéines (4) et Lcor Kits (2) et beaucoup plus de produits pour cette protéine.
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Bat Polyclonal Lcor Primary Antibody pour WB - ABIN611286
Davis-Smyth, Duncan, Zheng, Michelotti, Levens: The far upstream element-binding proteins comprise an ancient family of single-strand DNA-binding transactivators. dans The Journal of biological chemistry 1997
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Cow (Bovine) Polyclonal Lcor Primary Antibody pour WB - ABIN2780126
Kunieda, Park, Takeuchi, Kubo: Identification and characterization of Mlr1,2: two mouse homologues of Mblk-1, a transcription factor from the honeybee brain(1). dans FEBS letters 2003
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miR (Montrer MLXIP Anticorps)-199a promotes stem cell properties in mammary stem cells and breast cancer stem cells by directly repressing nuclear receptor corepressor LCOR, which primes interferon (Montrer IFNA Anticorps) responses.
These findings suggest that transactivation activities of Mlr1 and Mlr2 are differentially regulated by splicing variants of NOL4, which are expressed in a tissue-selective manner.
identification and characterization of Mlr2 a homolog of Mblk-1, a transcription factor from the honeybee brain; expressed in various tissues other than testis
Taken together, these results provide new insights into the mechanism of action of LCoR and RIP140 (Montrer NRIP1 Anticorps) and highlight their strong interplay for the control of gene expression and cell proliferation in breast cancer cells.
LCoR recruitment by KLF6 (Montrer KLF6 Anticorps) regulates expression of the cyclin-dependent kinase (Montrer CDK1 Anticorps) inhibitor CDKN1A gene.
Ligand-dependent corepressor acts as a novel androgen receptor corepressor, inhibits prostate cancer growth, and is functionally inactivated by the Src protein kinase.
These results showed that the presence of miR (Montrer MLXIP Anticorps)-615-3p repressed the expression of LCoR, a derepressor of peroxisome proliferator-activated receptor gamma (PPARgamma (Montrer PPARG Anticorps)).
Data show that LCoR (ligand-dependent nuclear receptor corepressor) represents a class of corepressor that attenuates agonist-activated nuclear receptor signaling by multiple mechanisms [Ligand-dependent nuclear receptor corepressor].
HDAC6 (Montrer HDAC6 Anticorps) can function as a cofactor of LCoR but they can act to enhance expression of specific estrogen-regulated genes
role for LCoR and CtBP1 (Montrer CTBP1 Anticorps) as attenuators of progesterone-regulated transcription, but LCoR and CtBP1 (Montrer CTBP1 Anticorps) can act to enhance transcription of some genes
LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor (NR) box (Fernandes et al., 2003
, ligand-dependent corepressor
, mblk1-related protein 2
, transcription factor MLR2
, ligand dependent nuclear receptor corepressor