Malate Dehydrogenase 1, NAD (Soluble) Protéines (MDH1)

Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. De plus, nous expédions Malate Dehydrogenase 1, NAD (Soluble) Anticorps (136) et Malate Dehydrogenase 1, NAD (Soluble) Kits (29) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
MDH1 4190 P40925
MDH1 17449 P14152
MDH1 24551 O88989
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Showing 10 out of 27 products:

Catalogue No. Origin Source Conjugué Images Quantité Livraison Prix Détails
Escherichia coli (E. coli) Humain His tag 100 μg 2 to 3 Days
$375.00
Détails
Escherichia coli (E. coli) Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 30 to 35 Days
$5,370.21
Détails
Escherichia coli (E. coli) Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 30 to 35 Days
$5,370.21
Détails
Escherichia coli (E. coli) Humain GST tag Malate Dehydrogenase 1, NAD (Soluble) (MDH1) (AA 2-333), (full length) protein (GST tag) 50 μg 13 to 16 Days
$242.00
Détails
Escherichia coli (E. coli) Humain His tag Validation with Western Blot 10 μg 4 to 8 Days
$394.90
Détails
Escherichia coli (E. coli) Rat His tag 50 μg 14 to 16 Days
$440.65
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
$888.80
Détails
Escherichia coli (E. coli) Humain His tag 100 μg 11 to 12 Days
$344.00
Détails
Wheat germ Humain GST tag 10 μg 11 to 12 Days
$414.29
Détails
Escherichia coli (E. coli) Humain His tag 100 μg 15 to 19 Days
$400.00
Détails

MDH1 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , ,
, , ,
Mouse (Murine)

Rat (Rattus) ,

Plus protéines pour Malate Dehydrogenase 1, NAD (Soluble) (MDH1) partenaires d'interaction

Human Malate Dehydrogenase 1, NAD (Soluble) (MDH1) interaction partners

  1. expression of miR-126-5p suppresses the enzymatic activity of MDH1, mitochondrial respiration and caused cell death in non-small cell lung carcinoma cell lines.

  2. Data show that in the endogenous readthrough of the human MDH1 stop codon, the stop codon can encode tryptophan and arginine, and is tissue-specific.

  3. Proliferating cells rely on both MDH1 and LDH to replenish cytosolic NAD.

  4. Arginine methylation of MDH1 by CARM1 regulates cellular redox homeostasis and suppresses glutamine metabolism of pancreatic cancer.

  5. adipogenic differentiation may be regulated by the acetylation of MDH1

  6. A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration.

  7. The MDH1 gene is not the cause of RP28-linked autosomal recessive retinitis pigmentosa.

  8. expression of MDH1 is maintained in the adult heart but is not present in levels as high as in the fetus

  9. Malate Dehydrogenase directly regulates the Tumor Suppressor Protein p53-dependent apoptosis upon glucose deprivation and involved in maintaining cellular metabolic state and further determining cell death.

  10. This protein has been found differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia.

Mouse (Murine) Malate Dehydrogenase 1, NAD (Soluble) (MDH1) interaction partners

  1. These findings provide strong evidence that MDH1 plays a critical role in osteoclast differentiation and function via modulation of the intracellular energy status, which might affect AMPK activity and NFATc1 expression.

  2. adipogenic differentiation may be regulated by the acetylation of MDH1

  3. Mor2 is an essential factor for oocyte maturation and embryo development in mouse.

Pig (Porcine) Malate Dehydrogenase 1, NAD (Soluble) (MDH1) interaction partners

  1. Structural features of the alphaB-crystallin oligomer when complexed with target proteins under mild stress conditions, i.e., reduction of alpha-lactalbumin at 37 degrees C and malate dehydrogenase when heated at 42 degrees C, were investigated.

  2. Both immunofluorescence and immunoelectron microscopy demonstrated cMDH at the plasma membrane of LLC-PK(1) cells.

Fruit Fly (Drosophila melanogaster) Malate Dehydrogenase 1, NAD (Soluble) (MDH1) interaction partners

  1. Observations on Mdh1 in both Gpdh and Adh backgrounds demonstrate significant increases in ethanol tolerance with partial reductions (50%) in cytosolic MDH activity.

Profil protéine Malate Dehydrogenase 1, NAD (Soluble) (MDH1)

Profil protéine

Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the cytoplasm and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene names and symbols associated with MDH1

  • malate dehydrogenase 1 (MDH1)
  • malate dehydrogenase 1, NAD (soluble) (Mdh1)
  • malate dehydrogenase 1 (Mdh1)
  • malate dehydrogenase 1 S homeolog (mdh1.S)
  • malate dehydrogenase, cytoplasmic (LOC100280767)
  • Malate dehydrogenase 1 (Mdh1)
  • B230377B03Rik Protéine
  • cMdh Protéine
  • D17921 Protéine
  • Mdh Protéine
  • Mdh-1 Protéine
  • mdh-s Protéine
  • Mdh2 Protéine
  • mdha Protéine
  • MdhD Protéine
  • Mdhl Protéine
  • MDL1 Protéine
  • MGC:1375 Protéine
  • Mor-2 Protéine
  • mor2 Protéine
  • sMdh Protéine

Protein level used designations for MDH1

cytosolic malate dehydrogenase , diiodophenylpyruvate reductase , malate dehydrogenase, cytoplasmic , soluble malate dehydrogenase , malate dehydrogenase, soluble , Malate dehydrogenase-like enzyme , malate dehydrogenase 1, NAD (soluble) , malate dehydrogenase, peroxisomal

GENE ID SPECIES
4190 Homo sapiens
17449 Mus musculus
24551 Rattus norvegicus
396894 Sus scrofa
398872 Xenopus laevis
493924 Felis catus
100280767 Zea mays
5656948 Drosophila melanogaster
421281 Gallus gallus
474614 Canis lupus familiaris
535182 Bos taurus
100734239 Cavia porcellus
694703 Macaca mulatta
101116035 Ovis aries musimon
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