anti-Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF) Anticorps

NSMAF encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. De plus, nous expédions Neutral Sphingomyelinase (N-SMase) Activation Associated Factor Kits (9) et Neutral Sphingomyelinase (N-SMase) Activation Associated Factor Protéines (5) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
NSMAF 8439 Q92636
NSMAF 18201 O35242
NSMAF 353233  
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Top anti-Neutral Sphingomyelinase (N-SMase) Activation Associated Factor Anticorps sur anticorps-enligne.fr

Showing 10 out of 52 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué IHC (p), WB WB Image Western Blot analysis of NSMAF expression in transfected 293T cell line by NSMAF polyclonal antibody. A: Non-transfected lysate. B: NSMAF transfected lysate. 7.5% SDS PAGE antibody diluted at 1:500 IHC-P Image Immunohistochemical analysis of paraffin-embedded human T(gastric cancer) , using NSMAF, antibody at 1:100 dilution. 100 μL Connectez-vous pour afficher 1 to 2 Days
$358.60
Détails
Souris Lapin Inconjugué IHC (p), WB NSMAF Antibody (N-term) (ABIN657508) western blot analysis in mouse cerebellum tissue lysates (35 µg/lane). This demonstrates the NSMAF antibody detected the NSMAF protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Lapin Inconjugué IHC (p), IHC, WB Immunohistochemistry-Paraffin: NSMAF Antibody [NBP1-31431] - Paraffin-embedded T(gastric CA), using antibody at 1:100 dilution. Western Blot: NSMAF Antibody [NBP1-31431] - Analysis of NSMAF expression in transfected 293T cell line by NSMAF polyclonal antibody. A: Non-transfected lysate. B: NSMAF transfected lysate. 7.5% SDS PAGE, antibody diluted at 1:500. 0.1 mL Connectez-vous pour afficher 8 to 11 Days
$514.63
Détails
Humain Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 7 to 9 Days
$537.17
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: NSMAF Antibody [NBP1-84735] - Staining of human cell line A-431 shows positivity in nucleoli. Immunohistochemistry-Paraffin: NSMAF Antibody [NBP1-84735] - Staining of human thyroid gland shows strong nuclear and cytoplasmic positivity in glandular cells. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$491.63
Détails
Humain Lapin Inconjugué IHC, IHC (p) Immunohistochemistry: NSMAF Antibody [NBP1-84737] - Staining of human oral mucosa shows strong nuclear positivity in squamous epithelial cells. Immunohistochemistry-Paraffin: NSMAF Antibody  - Staining of human tonsil shows moderate cytoplasmic positivity in both germinal and non-germinal center cells. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$491.63
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB Immunohistochemistry: NSMAF Antibody [NBP1-84736] - Staining of human colon shows moderate cytoplasmic positivity in glandular cells. Western Blot: NSMAF Antibody [NBP1-84736] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY418576) 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$491.63
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB   100 μL Connectez-vous pour afficher 7 to 9 Days
$507.83
Détails
Humain Lapin Inconjugué IF (p), IHC (p), WB Paraformaldehyde-fixed, paraffin embedded Mouse intestines, Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes, Blocking buffer (normal goat serum) at 37°C for 30min, Antibody incubation with NSMAF Polyclonal Antibody, Unconjugated  at 1:400 overnight at 4°C, followed by a conjugated secondary antibody for 20 minutes and DAB staining. Paraformaldehyde-fixed, paraffin embedded Mouse stomach, Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes, Blocking buffer (normal goat serum) at 37°C for 30min, Antibody incubation with NSMAF Polyclonal Antibody, Unconjugated  at 1:400 overnight at 4°C, followed by a conjugated secondary antibody for 20 minutes and DAB staining. 100 μL Connectez-vous pour afficher 14 to 21 Days
$306.90
Détails
Souris Lapin Inconjugué IHC, ELISA, WB   200 μL Connectez-vous pour afficher 11 to 16 Days
$594.00
Détails

Plus d’anticorps contre Neutral Sphingomyelinase (N-SMase) Activation Associated Factor partenaires d’interaction

Human Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF) interaction partners

  1. The interaction of FAN with receptor for activated C-kinase 1 (RACK1 (Montrer GNB2L1 Anticorps)) appears to be dependent on the folding of the WD repeats into a secondary structure, because no linear binding motifs are identified in the WD-repeat region of FAN.

  2. sphingolipid activator proteins like domain may stabilize the fold of acid sphingomyelinase (Montrer SMPD1 Anticorps)

  3. Regulation of NSMAF by TNF-alpha (Montrer TNF Anticorps) involves PRKCD (Montrer PKCd Anticorps) in lung epithelial cells.

Mouse (Murine) Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF) interaction partners

  1. FAN through promoting melanoma cellular motility and tumour invasiveness is critical for the tumour-promoting action of tumor necrosis factor (Montrer TNF Anticorps).

  2. FAN is not implicated in the development of methionine and choline deficient diet-induced non-alcoholic steatohepatitis.

  3. the role of FAN and IL-6 (Montrer IL6 Anticorps) in the inflammatory response initiated by endotoxin, implicating TNFalpha (Montrer TNF Anticorps)

  4. FAN mediates activation of N-SMase as well as regulation of lysosome size by signaling pathways that operate independent from activation/membrane recruitment of PKC.

  5. The results of this study suggest that PH-mediated plasma membrane targeting of FAN is critically involved in tumor necrosis factor (Montrer TNF Anticorps)-induced Cdc42 (Montrer CDC42 Anticorps) activation and cytoskeleton reorganization.

  6. This is the first report to demonstrate that TNFalpha (Montrer TNF Anticorps)-induced sickness behavior is fully mediated by TNF-R1 (Montrer TNFRSF1A Anticorps) and that the adaptor protein FAN is a necessary intracellular intermediate for sickness behavior

  7. these results indicate the involvement of FAN in TNF (Montrer TNF Anticorps)-induced gene expression and leukocyte recruitment, contributing to the establishment of the specific immune response.

Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF) profil antigène

Profil protéine

This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with NSMAF

  • protein FAN (EDI_035100) anticorps
  • neutral sphingomyelinase activation associated factor (NSMAF) anticorps
  • neutral sphingomyelinase (N-SMase) activation associated factor (Nsmaf) anticorps
  • neutral sphingomyelinase activation associated factor (Nsmaf) anticorps
  • AA959567 anticorps
  • C630007J05 anticorps
  • Fan anticorps

Protein level used designations for NSMAF

protein FAN , factor associated with N-SMase activation , factor associated with neutral sphingomyelinase activation

GENE ID SPECIES
5884688 Entamoeba dispar SAW760
8439 Homo sapiens
18201 Mus musculus
353233 Rattus norvegicus
Fournisseurs de qualité sélectionnés pour anti-Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF) Anticorps
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