anti-Phosphoinositide-Interacting Regulator of Transient Receptor Potential Channels (PIRT) Anticorps

Regulatory subunit of TRPV1, a molecular sensor of noxious heat and capsaicin. De plus, nous expédions et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
PIRT 644139 P0C851
PIRT 193003 Q8BFY0
PIRT 497929  
Comment commander chez anticorps-enligne
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Commandez enligne
  • orders@anticorps-enligne.fr

Top anti-PIRT Anticorps sur anticorps-enligne.fr

Showing 10 out of 15 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Humain Lapin Cy3 IF (p)   100 μL 14 to 21 Days
$416.90
Détails
Humain Lapin Cy7 IF (p)   100 μL 14 to 21 Days
$416.90
Détails
Humain Lapin Alexa Fluor 488 IF (p)   100 μL 14 to 21 Days
$416.90
Détails
Humain Lapin Alexa Fluor 647 IF (p)   100 μL 14 to 21 Days
$416.90
Détails
Humain Lapin Alexa Fluor 350 IF (p)   100 μL 14 to 21 Days
$416.90
Détails
Humain Lapin FITC IF (p)   100 μL 14 to 21 Days
$416.90
Détails
Humain Lapin Alexa Fluor 555 IF (p)   100 μL 14 to 21 Days
$416.90
Détails
Humain Lapin Cy5 IF (p)   100 μL 14 to 21 Days
$416.90
Détails
Humain Lapin HRP IHC (p)   100 μL 14 to 21 Days
$416.90
Détails
Humain Lapin Cy5.5 IF (p)   100 μL 14 to 21 Days
$416.90
Détails

Plus d’anticorps contre PIRT partenaires d’interaction

Human Phosphoinositide-Interacting Regulator of Transient Receptor Potential Channels (PIRT) interaction partners

  1. These results have uncovered species-specific TRPM8 modulation by PIRT. They provide evidence for a direct interaction between PIRT and the TRPM8 S1-S4 domain with a 1:1 binding stoichiometry, suggesting that a functional tetrameric TRPM8 channel has four PIRT-binding sites.

Mouse (Murine) Phosphoinositide-Interacting Regulator of Transient Receptor Potential Channels (PIRT) interaction partners

  1. Using comparative electrophysiology experiments, the study identified species-dependent differences between the human and mouse TRPM8-PIRT complexes. It found that human PIRT attenuated human TPRM8 conductance, unlike mouse PIRT, which enhanced mouse TRPM8 conductance.

  2. Results show that mechanical allodynia and thermal hyperalgesia were alleviated in Pirt-/- mice in chronic constriction injury (CCI) model. Taken together, Pirt together with transient receptor potential vanilloid channel 1 is involved in CCI-induced neuropathic pain.

  3. Pirt regulates TRPM8 channel activity by increasing the single channel conductance.

  4. These results demonstrate that Pirt is an endogenous regulator of P2X3 in bladder function.

  5. Pirt plays an important role in mice uterine contraction-induced pain.

  6. Pirt regulates the function of TRPM8 and its role in detecting cold.

  7. Pirt contributes to both histaminergic and nonhistaminergic itch and, crucially, is involved in forms of itch that are both TRPV1-dependent and -independent.

  8. Pirt is a key component of the TRPV1 complex and positively regulates TRPV1 activity.

PIRT profil antigène

Profil protéine

Regulatory subunit of TRPV1, a molecular sensor of noxious heat and capsaicin. Positively regulates TRPV1 channel activity via phosphatidylinositol 4,5-bisphosphate (PIP2). Binds various phosphoinositide, including phosphatidylinositol 4,5- bisphosphate (PIP2), but not phosphatidylinositol (PI) (By similarity).

Gene names and symbols associated with PIRT

  • phosphoinositide interacting regulator of transient receptor potential channels (PIRT) anticorps
  • phosphoinositide-interacting regulator of transient receptor potential channels (Pirt) anticorps
  • A530088H08Rik anticorps
  • RGD1565284 anticorps

Protein level used designations for PIRT

phosphoinositide-interacting protein , phosphoinositide-interacting regulator of TRPV1 , phosphoinositide interacting protein

GENE ID SPECIES
644139 Homo sapiens
193003 Mus musculus
100686498 Canis lupus familiaris
100140752 Bos taurus
497929 Rattus norvegicus
Fournisseurs de qualité sélectionnés pour anti-PIRT (PIRT) Anticorps
Avez-vous cherché autre chose?