Profil protéine

This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with RASD1

• ras related dexamethasone induced 1 (RASD1) anticorps
• RAS, dexamethasone-induced 1 (Rasd1) anticorps
• ras related dexamethasone induced 1 (Rasd1) anticorps

• AGS1 anticorps
• Dexras1 anticorps
• MGC:26290 anticorps

Protein level used designations for RASD1

activator of G-protein signaling 1 , dexamethasone-induced Ras-related protein 1 , ras-related protein , DEXRAS1 (Dexras1)