anti-Retinol Binding Protein 1, Cellular (RBP1) Anticorps

RBP1 encodes the carrier protein involved in the transport of retinol (vitamin A alcohol) from the liver storage site to peripheral tissue. De plus, nous expédions Retinol Binding Protein 1, Cellular Kits (27) et Retinol Binding Protein 1, Cellular Protéines (16) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
RBP1 5947 P09455
RBP1 19659 Q00915
RBP1 25056 P02696
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Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Chèvre Inconjugué ELISA, FACS, IF, WB ABIN185365 (0.1µg/ml) staining of NIH 3T3 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN185365 (2µg/ml) staining of NIH3T3 (A) and (0.5ug/ml) of U251 (B) cell lysate (35µg protein in RIPA buffer). Detected by chemiluminescence. 100 μg Connectez-vous pour afficher 6 to 7 Days
$429.84
Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-RBP1 Antibody Titration:  2.5ug/ml  Positive Control:  HCT116 cell lysate RBP1 is supported by BioGPS gene expression data to be expressed in HCT116 100 μL Connectez-vous pour afficher 2 to 3 Days
$229.00
Détails
Humain Souris Inconjugué FACS, IF, IHC, IHC (p), WB 100 μL Connectez-vous pour afficher 11 to 14 Days
$522.50
Détails
Humain Lapin Inconjugué ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Porcine Liver Tissue; Lane2: Human Liver Tissue; Lane3: Rat Testis Tissue; Lane4: Human 293T Cells. 100 μg Connectez-vous pour afficher 15 to 18 Days
$316.00
Détails
Humain Chèvre Inconjugué ELISA, IHC, IHC (p), WB Human Liver (formalin-fixed, paraffin-embedded) stained with RBP1 antibody ABIN462286 followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. Human Pancreas (formalin-fixed, paraffin-embedded) stained with RBP1 antibody ABIN462286 followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg Connectez-vous pour afficher 11 to 14 Days
$484.00
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 11 to 14 Days
$493.17
Détails
Humain Souris Inconjugué FACS, IF, IHC, WB Anti-RBP1 mouse monoclonal antibody (ABIN2454526) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RBP1 (RC214515). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RBP1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-RBP1. 0.1 mL Connectez-vous pour afficher 2 to 3 Days
$462.00
Détails
Humain Chèvre Inconjugué EIA, IHC (p), WB Human Liver (formalin-fixed, paraffin-embedded) stained with RBP1followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Human Pancreas (formalin-fixed, paraffin-embedded) stained with RBP1followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. 50 μg Connectez-vous pour afficher 6 to 8 Days
$495.00
Détails
Humain Souris Inconjugué FACS, IF, IHC (p), WB Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human pancreas with RBP1 monoclonal antibody, clone 2E1 . Immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RBP1 with RBP1 monoclonal antibody, clone 2E1 . 50 μL Connectez-vous pour afficher 11 to 12 Days
$637.32
Détails
Souris Lapin Inconjugué WB Western blot analysis of extracts of mouse lung and rat liver cells, using RBP1 antibody. Western blot analysis of extracts of rat liver, using RBP1 antibody (ABIN4904977) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s. 100 μL Connectez-vous pour afficher 11 to 13 Days
$366.77
Détails

anti-Retinol Binding Protein 1, Cellular Anticorps mieux référencés

  1. Human Polyclonal RBP1 Primary Antibody pour ELISA, WB - ABIN547410 : Bilbija, Haugen, Sagave, Baysa, Bastani, Levy, Sirsjö, Blomhoff, Valen: Retinoic acid signalling is activated in the postischemic heart and may influence remodelling. dans PLoS ONE 2012 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre Retinol Binding Protein 1, Cellular partenaires d’interaction

Human Retinol Binding Protein 1, Cellular (RBP1) interaction partners

  1. Up-regulated expression of CRBP-1 is associated with poor prognosis in tongue squamous cell carcinoma

  2. molecular dynamics simulations for the uptake of retinol by CRBP 1 and 2

  3. Low CRBP1 expression is associated with low radiation sensitivity in rectal cancer.

  4. This conformational flexibility of human apo-CRBP1 facilitates interaction with the ligands, whereas the more rigid holoprotein structure protects the labile retinoid moiety during vitamin A transport.

  5. Hypermethylation of CRBP1 gene is associated with Epstein-Barr virus-associated gastric carcinomas.

  6. Further studies are needed to explore new therapeutic strategies aimed at restoring CRBP-1-mediated intracellular retinol trafficking and the meaning of CRBP-1 expression in cancer patients screening for a more personalized and efficacy retinoid therapy

  7. RBP1 expression was reduced in tissue and endometrial stromal cells derived from endometritis lesions versus eutopic endometruim in humans and mice.

  8. Functional hepatic stellate cells coexpressing both LRAT and CRBP-1, that continue to maintain the ability to store vitamin A, contribute in part to the development of portal and parenchymal fibrogenesis in patients with viral hepatitis.

  9. Factors involved in the retinoid pathway, in particular upregulation of CRBP, CRABP1 and CRABP2, also showed differential expression in tumors with different histological subtypes

  10. CRBP-1 loss in G2/G3 ovarian carcinomas and increased apoptotic susceptibility to retinoids.

  11. Suggest CRBP1 gene as a tumor suppressor gene for cervical cancer.

  12. High urine retinol binding protein is associated with interstitial fibrosis and tubular atrophy plus inflammation.

  13. RBP1 promoter hypermethylation is found in nearly all IDH1 and IDH2 mutant gliomas Because RBP1 is involved in retinoic acid synthesis, results suggest that dysregltion of RA metabolism may contribute to glioma formation along the IDH1/IDH2-mutant pathway

  14. CRBP-1 plays a role in ventricular remodeling after myocardial infarction allegedly through its RA binding activity.

  15. Increased expression and unmethylated promoter of the CRBP1 gene could be considered as markers for larynx cancer.

  16. Data show that CRBPI and CRBPII bind 9-cis-retinol and 9-cis-retinal with high affinities, albeit with affinities somewhat lower than for all-trans-retinol and all-trans-retinal.

  17. STRA6 not only is a vitamin A transporter but also is a cell-surface signaling receptor activated by the RBP-retinol complex.

  18. CDK-mediated phosphorylation of both RBP1 and pRb induces their dissociation to mediate release of the mSin3.HDAC transcriptional repressor complex from pRb to alleviate transcriptional repression of E2F.

  19. CRBP1 gene could have a tumor suppressive function in bladder cancer.

  20. It is likely that mutations in RGR, RBP3, and possibly RBP1 occur rarely in inherited retinal dystrophies.

Xenopus laevis Retinol Binding Protein 1, Cellular (RBP1) interaction partners

  1. The localization of CRBP1 within the retina and its demonstrated role in modulating the proper folding of nascent outer segment membranes through retinoic acid further elucidates the role of these cells in directly influencing photoreceptor physiology.

Mouse (Murine) Retinol Binding Protein 1, Cellular (RBP1) interaction partners

  1. genetic deletion of RBP1 and RBP2 did not impair synapse ultrastructure of ribbon-type synapses formed between rod bipolar cells (RBCs) and amacrine type-2 (AII) cells in the mouse retina but dramatically reduced the density of presynaptic Ca(2+) channels, decreased and desynchronized evoked neurotransmitter release

  2. RBPs perform unexpectedly broad roles at the active zone that together with those of RIMs are essential for all active zone functions.

  3. RBP1 expression was reduced in tissue and endometrial stromal cells derived from endometritis lesions versus eutopic endometruim in humans and mice.

  4. CrbpI loss disrupts all-trans retinoic acid homeostasis in mammary tissue, resulting in microenvironmental defects similar to those observed at the early stages of tumorigenesis.

  5. glucose homeostasis and energy metabolism rely on Rbp1 expression and its moderation of pancreas retinol and of the autacoid 9-cis-retinoic acid.

  6. As such, the effects of RBP1 on these processes are mediated through both regulation of Runx2 expression and transcriptional activity.

  7. CRBP-I is a cytosolic protein specifically expressed in preadipocytes that regulates adipocyte differentiation in part by affecting PPAR gamma activity.

  8. This murine RBP-null model may have relevance to fetal development in human populations with inadequate retinoid intake.

  9. Crbp1-/- mice also exhibited increased metabolism of a dose of retinol into retinoic acid, and this increased metabolism was not observed in Crbp1-/-/Adh1-/- mice

  10. Data show that while vitamin A-replete retinol binding protein (rbp)-cryptochrome(cry) 1- and 2-knockout mice are light responsive, vitamin A-depleted knockout mice lose most behavioral and molecular responses to light.

  11. Epigenetic silencing of cellular CRBPI is associated with nasopharyngeal carcinoma

Retinol Binding Protein 1, Cellular (RBP1) profil antigène

Profil protéine

This gene encodes the carrier protein involved in the transport of retinol (vitamin A alcohol) from the liver storage site to peripheral tissue. Vitamin A is a fat-soluble vitamin necessary for growth, reproduction, differentiation of epithelial tissues, and vision. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with RBP1

  • retinol binding protein 1 (RBP1) anticorps
  • retinol binding protein 1a, cellular (rbp5) anticorps
  • retinol binding protein 1 L homeolog (rbp1.L) anticorps
  • retinol binding protein 1 (rbp1) anticorps
  • retinol binding protein 1, cellular (Rbp1) anticorps
  • retinol binding protein 1 (Rbp1) anticorps
  • retinol binding protein 1, cellular (RBP1) anticorps
  • cb465 anticorps
  • CRABP-I anticorps
  • CRABP1 anticorps
  • Crbp anticorps
  • CRBP1 anticorps
  • CRBPI anticorps
  • Rbp-1 anticorps
  • rbp1 anticorps
  • RBPC anticorps
  • wu:fb75e07 anticorps
  • zgc:73335 anticorps

Protein level used designations for RBP1

CRBP-I , cellular retinol-binding protein I , retinol-binding protein 1 , retinol-binding protein 1, cellular , retinol binding protein 1, cellular , CRBP , cellular retinol binding protein 1 , mCRBPI , LOW QUALITY PROTEIN: retinol-binding protein 1

GENE ID SPECIES
5947 Homo sapiens
171477 Danio rerio
414642 Xenopus laevis
537379 Bos taurus
100156666 Sus scrofa
100216164 Xenopus (Silurana) tropicalis
100228240 Taeniopygia guttata
19659 Mus musculus
25056 Rattus norvegicus
424821 Gallus gallus
477090 Canis lupus familiaris
101787202 Cavia porcellus
100354448 Oryctolagus cuniculus
102189996 Capra hircus
743893 Pan troglodytes
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