anti-SPO11 Meiotic Protein Covalently Bound To DSB Homolog (S. Cerevisiae) (SPO11) Anticorps

Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. De plus, nous expédions SPO11 Protéines (5) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
SPO11 23626 Q9Y5K1
SPO11 366261  
SPO11 26972 Q9WTK8
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Top anti-SPO11 Anticorps sur anticorps-enligne.fr

Showing 10 out of 61 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB Host: Rabbit Target Name: SPO11 Sample Tissue: Human 293T Antibody Dilution: 1.0ug/ml WB Suggested Anti-SPO11 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: HepG2 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué WB Western Blot: SPO11 Antibody [NBP1-58172] - Sample Tissue: Human 293T Antibody Dilution: 1.0 ug/ml Western Blot: SPO11 Antibody [NBP1-58172] - HepG2 cell lysate, concentration 0.2-1 ug/ml. 100 μL Connectez-vous pour afficher 8 to 11 Days
$447.56
Détails
Humain Lapin Inconjugué WB SPO11 Antibody (C-term)  western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the SPO11 antibody detected the SPO11 protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails
Humain Lapin Inconjugué ELISA, WB 50 μg Connectez-vous pour afficher 2 to 3 Days
$433.13
Détails
Humain Lapin Inconjugué WB Western Blot: SPO11 Antibody [NBP2-20475] - Sample (30 ug of whole cell lysate) A: NT2D1 10% SDS PAGE gel, diluted at 1:1000. 0.1 mL Connectez-vous pour afficher 8 to 11 Days
$447.56
Détails
Humain Lapin Alexa Fluor 555 IF (p)   100 μL Connectez-vous pour afficher 14 to 21 Days
$405.90
Détails
Humain Lapin Alexa Fluor 350 IF (p)   100 μL Connectez-vous pour afficher 14 to 21 Days
$405.90
Détails
Humain Lapin Alexa Fluor 488 IF (p)   100 μL Connectez-vous pour afficher 14 to 21 Days
$405.90
Détails
Humain Lapin Alexa Fluor 647 IF (p)   100 μL Connectez-vous pour afficher 14 to 21 Days
$405.90
Détails

SPO11 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-SPO11 Anticorps mieux référencés

  1. Human Polyclonal SPO11 Primary Antibody pour WB - ABIN4891847 : Suberbielle, Sanchez, Kravitz, Wang, Ho, Eilertson, Devidze, Kreitzer, Mucke: Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β. dans Nature neuroscience 2013 (PubMed)

Plus d’anticorps contre SPO11 partenaires d’interaction

Human SPO11 Meiotic Protein Covalently Bound To DSB Homolog (S. Cerevisiae) (SPO11) interaction partners

  1. SPO11 gene C631T polymorphism may contribute as a genetic factor susceptible to cause male infertility in Chinese.

  2. Data suggest that the combined genotypes of glutathionine S-transferase GSTM1 (-/-), GSTT1 (+/+), GSTP1 (AA) and meiotic recombination protein SPO11 (CT) may be associated with idiopathic male infertility in ethnic Han Chinese.

  3. Polymorphisms within the SPO11 gene are linked to the susceptibility of azoospermia and oligozoospermia male infertility.

  4. SPO11 might has an effect on premorbid functioning, which increase susceptibility for idiopathic male reproduction

  5. Mutations in the human SPO11 gene are not common causes of infertility in man

  6. Data show that there is no association between SPO11 gene mutation and premature ovarian failure.

Mouse (Murine) SPO11 Meiotic Protein Covalently Bound To DSB Homolog (S. Cerevisiae) (SPO11) interaction partners

  1. These data suggest that Tex19.1 and Ubr2 (Montrer UBR2 Anticorps) are required for mouse spermatocytes to accumulate sufficient Spo11-dependent recombination to ensure that the homology search is consistently successful, and reveal a hitherto unknown genetic pathway promoting meiotic recombination in mammals.

  2. If SPO11 expression is reduced and DNA double-strand breaks at zygonema are decreased (approximately 40 % below wild-type level), meiotic chromosome pairing is normal.

  3. suppression of genetic recombination in the pseudoautosomal region and at subtelomeres in mice with a hypomorphic Spo11 allele

  4. our results indicate that in addition to asynapsis, persistent SPO11-induced DSBs are important for the initiation of MSCI and MSUC, and that SPO11-independent DNA repair foci contribute to the MSUC response in oocytes.

  5. Mice with greater or fewer copies of the Spo11 gene--with correspondingly greater or fewer numbers of early recombination foci--exhibited relatively invariant crossover numbers.

  6. chromosome synapsis defects and sexually dimorphic meiotic progression in Spo11 deficient mice

  7. Spo11 is not required for Ig hypermutation or class switch recombination

  8. In Spo11 -/- cells, SMC1 (Montrer SMC1A Anticorps) localization on meiotic chromosomes is mainly associated with homologous or non-homologous synapsed regions, whereas SMC3 (Montrer SMC3 Anticorps) localized throughout the chromosomes. Both localized along chromosome cores of Spo11 null spermatocytes.

  9. meiotic double-stranded breaks are processed by endonucleolytic cleavage that releases Spo11 attached to an oligonucleotide with a free 3'-OH

  10. The presence of these L-foci in Spo11(-/-) spermatocytes raises the interesting possibility of yet uncharacterized alterations in DNA or chromosome structure in Spo11(-/-) cells.

SPO11 profil antigène

Profil protéine

Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described.

Gene names and symbols associated with SPO11

  • Meiotic recombination protein spo-11 (spo-11) anticorps
  • SPO11, initiator of meiotic double stranded breaks (SPO11) anticorps
  • SPO11, initiator of meiotic double stranded breaks (Spo11) anticorps
  • SPO11 meiotic protein covalently bound to DSB (spo11) anticorps
  • SPO11 meiotic protein covalently bound to DSB (Spo11) anticorps
  • AI449549 anticorps
  • CT35 anticorps
  • SPATA43 anticorps
  • TOPVIA anticorps
  • zgc:77876 anticorps

Protein level used designations for SPO11

SPO11 meiotic protein covalently bound to DSB homolog , cancer/testis antigen 35 , meiotic recombination protein SPO11 , spermatogenesis associated 43 , sporulation protein, meiosis-specific, SPO11 homolog , sporulation protein, meiosis-specific, SPO11 , sporulation protein, meiosis-specific, SPO11 homolog (S. cervisiae)

GENE ID SPECIES
191771 Caenorhabditis elegans
23626 Homo sapiens
366261 Rattus norvegicus
402982 Danio rerio
610247 Canis lupus familiaris
100125974 Sus scrofa
524105 Bos taurus
26972 Mus musculus
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