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SLC16A7 is a member of the monocarboxylate transporter family.
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Mouse (Murine) Polyclonal SLC16A7 Primary Antibody pour IHC - ABIN966548
Koehler-Stec, Simpson, Vannucci, Landschulz, Landschulz: Monocarboxylate transporter expression in mouse brain. dans The American journal of physiology 1998
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Human Polyclonal SLC16A7 Primary Antibody pour ELISA, WB - ABIN268640
Lin, Vera, Chaganti, Golde: Human monocarboxylate transporter 2 (MCT2) is a high affinity pyruvate transporter. dans The Journal of biological chemistry 1998
SLC16A7 (MCT2) epigenetic regulation results in protein over-expression, affecting signalling and cellular phenotypes in prostate cancer
Data suggest that monocarboxylate transporter 2 (MCT2) at peroxisomes is related to an increase in beta-oxidation levels which may be crucial for malignant transformation.
This study identified that CGPs was found to significantly correlate with the differential expression and methylation of genes encoding solute carrier (Montrer SERTAD2 Anticorps) family 16, member 7.
Our findings suggest that SNPs in MCT1 (Montrer CMA1 Anticorps) and MCT2 genes may affect clinical outcomes and can be used to predict the response to adjuvant chemotherapy in NSCLC patients who received surgical treatment once validated in future study.
SNPs in MCT1 (Montrer CMA1 Anticorps) and MCT2 genes may affect clinical outcomes and can be used to predict the response to adjuvant chemotherapy in CRC (Montrer CALR Anticorps) patients who received surgical treatment.
MCT2-3' UTR (Montrer UTS2R Anticorps) SNP (+2626 G > A) had a strong association with oligoasthenoteratozoospermia.
this study provided evidence for the presence of MCT2 in prostate cancer, selectively labeling malignant glands.
The monocarboxylate transporter 2 (MCT2) protein was tumor-selectively expressed in human colorectal malignancies and knockdown of MCT2 induces mitochondrial dysfunction, cell-cycle arrest, and senescence.
Light microscopic immunohistochemistry revealed significantly less perivascular MCT2 immunoreactivity in the hippocampal formation in medial temporal lobe epilepsy than in non-MTLE patients
Data show that a significant increase of MCT2 and MCT4 (Montrer SLC16A4 Anticorps) expression in the cytoplasm of tumour cells and a significant decrease in both MCT1 (Montrer CMA1 Anticorps) and CD147 expression in prostate tumour cells was observed when compared to normal tissue.
These results suggest that basigin has a functional role as a binding partner with MCT2 in testicular and epididymal spermatozoa.
This study demonstrated that MCT2 was up regulation in ipsilateral site of brain afeter cerebral ischemia.
MCT2 distribution coupled with lactate uptake by hypothalamic neurons suggests that hypothalamic neurons control food intake using lactate to reflect changes in glucose levels.
Data suggest that basigin interacts with MCT1 (Montrer MCTS1 Anticorps) and MCT2 to locate them properly in the membrane of spermatogenic cells and that this may enable sperm to utilize lactate as an energy substrate contributing to cell survival.
Glucose-deprived cleavage stage embryos, undergo oxidative stress and exhibit elevated ROS (Montrer ROS1 Anticorps), which in turn upregulates PPARA (Montrer PPARA Anticorps), catalase (Montrer CAT Anticorps) and SLC16A7 in a classical peroxisomal proliferation response.
These results demonstrate that MCT2 expression can be upregulated together with other key postsynaptic proteins in vivo under conditions related to synaptic plasticity
changes in MCT2 expression could participate in the process of synaptic plasticity induced by BDNF (Montrer BDNF Anticorps)
data provide convincing evidence that MCT2 represents a major neuronal monocarboxylate transporter in the adult mouse brain
In mouse cortical neurons MCT2 is the major monocarboxylate transporter; its expression is correlated with synaptic development.
Regulation of expression of MCT1 (Montrer MCTS1 Anticorps) and MCT2 was investigated in mouse cortical neurons; neither noradrenaline, dibutyryl cAMP nor forskolin affected MCT2 mRNA expression
immunohistochemical studies localized MCT2, MCT7 (Montrer MCT7 Anticorps), and MCT8 (Montrer MCT8 Anticorps) proteins in the cattle rumen, abomasum, jejunum, and caecum.
Data indicate that monocarboxylate transporters (MCTs1 (Montrer MCTS1 Anticorps)-4) were all found to be expressed in brains of embryos, and were localized in both neurons and astrocyte.
This gene is a member of the monocarboxylate transporter family. Members in this family transport metabolites, such as lactate, pyruvate, and ketone bodies. The protein encoded by this gene catalyzes the proton-linked transport of monocarboxylates and has the highest affinity for pyruvate. This protein has been reported to be more highly expressed in prostate and colorectal cancer specimens when compared to control specimens. Alternative splicing results in multiple transcript variants.
monocarboxylate transporter 2
, solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
, MCT 2
, solute carrier family 16 member 7
, solute carrier family 16 (monocarboxylic acid transporters), member 7
, Solute carrier family 16 member 7