anti-Solute Carrier Family 18 (Vesicular Acetylcholine), Member 3 (SLC18A3) Anticorps

SLC18A3 is a member of the vesicular amine transporter family. De plus, nous expédions Solute Carrier Family 18 (Vesicular Acetylcholine), Member 3 Kits (10) et Solute Carrier Family 18 (Vesicular Acetylcholine), Member 3 Protéines (3) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
SLC18A3 60422 Q62666
SLC18A3 6572 Q16572
SLC18A3 20508  
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Top anti-Solute Carrier Family 18 (Vesicular Acetylcholine), Member 3 Anticorps sur anticorps-enligne.fr

Showing 10 out of 125 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Rat Cobaye Inconjugué IHC, WB 50 μg 5 to 6 Days
$497.20
Détails
Humain Lapin Inconjugué WB Western blot analysis of SLC18A3 expression in HELA whole cell lysates ( Lane 1) and HEPA whole cell lysates ( Lane 2). SLC18A3 at 55KD was detected using rabbit anti- SLC18A3 Antigen Affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002). 100 μg 4 to 6 Days
$240.00
Détails
Humain Lapin Inconjugué IHC, WB IHC on rat spinal cord (paraffin section) using Rabbit antibody to (Vesicular Acetylcholine Transporter) VACHT: whole serum  at 1 : 200 dilution incubated overnight at 4C, developed with DAB/Ni and counterstained with hematoxylin. IHC on rat spinal cord (paraffin section) using Rabbit antibody to VACHT  at 1 : 200 dilution incubated overnight at 4C, developed with DAB/Ni and counterstained with hematoxylin. 100 μL 7 to 8 Days
$454.67
Détails
Humain Lapin Inconjugué IHC, WB IHC on rat spinal cord (free floating sections) using Rabbit antibody to VACHT (90-140)  at 1 : 300 dilution, incubated overnight at 4C, developed with DAB/Ni. IHC on rat spinal cord (free floating sections) using RRabbit antibody to VACHT (90-140)  at 1 : 300 dilution, incubated overnight at 4C, developed with DAB/Ni. 100 μL 7 to 8 Days
$454.67
Détails
Humain Souris Inconjugué ICC, IF, IHC, WB western rat membrane 1 in 1000 VACht. 100 μg 3 to 4 Days
$453.70
Détails
Souris Lapin Inconjugué IHC, WB IHC on rat spinal cord (paraffin section) using Rabbit antibody to VACHT  at 1 : 200 dilution incubated overnight at 4C, developed with DAB/Ni and counterstained with hematoxylin. IHC on rat spinal cord (paraffin section) using Rabbit antibody to VACHT  at 1 : 200 dilution incubated overnight at 4C, developed with DAB/Ni and counterstained with hematoxylin. 100 μL 7 to 8 Days
$454.67
Détails
Humain Souris FITC ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-VAChT Monoclonal Antibody, Clone S6-38 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-VAChT Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:200 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Membrane. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) VAChT Antibody (D) Composite. Western Blot analysis of Rat brain membrane lysate showing detection of VAChT protein using Mouse Anti-VAChT Monoclonal Antibody, Clone S6-38 . Primary Antibody: Mouse Anti-VAChT Monoclonal Antibody  at 1:1000. 100 μg 3 to 4 Days
$504.40
Détails
Humain Souris PerCP ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-VAChT Monoclonal Antibody, Clone S6-38 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-VAChT Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:200 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Membrane. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) VAChT Antibody (D) Composite. Western Blot analysis of Rat brain membrane lysate showing detection of VAChT protein using Mouse Anti-VAChT Monoclonal Antibody, Clone S6-38 . Primary Antibody: Mouse Anti-VAChT Monoclonal Antibody  at 1:1000. 100 μg 3 to 4 Days
$513.50
Détails
Humain Souris APC ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-VAChT Monoclonal Antibody, Clone S6-38 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-VAChT Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:200 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Membrane. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) VAChT Antibody (D) Composite. Western Blot analysis of Rat brain membrane lysate showing detection of VAChT protein using Mouse Anti-VAChT Monoclonal Antibody, Clone S6-38 . Primary Antibody: Mouse Anti-VAChT Monoclonal Antibody  at 1:1000. 100 μg 3 to 4 Days
$513.50
Détails
Humain Souris Atto 488 ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-VAChT Monoclonal Antibody, Clone S6-38 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-VAChT Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:200 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Membrane. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) VAChT Antibody (D) Composite. Western Blot analysis of Rat brain membrane lysate showing detection of VAChT protein using Mouse Anti-VAChT Monoclonal Antibody, Clone S6-38 . Primary Antibody: Mouse Anti-VAChT Monoclonal Antibody  at 1:1000. 100 μg 3 to 4 Days
$514.80
Détails

anti-Solute Carrier Family 18 (Vesicular Acetylcholine), Member 3 Anticorps mieux référencés

  1. Human Polyclonal SLC18A3 Primary Antibody pour IEM, ICC - ABIN1526179 : Wang, Guan, Ochiai, Nakai: An electron microscopic observation of the vesicular acetylcholine transporter-immunoreactive fibers in the rat dorsal raphe nucleus. dans Brain research bulletin 1998 (PubMed)
    Show all 20 Pubmed References

  2. Mammalian Monoclonal SLC18A3 Primary Antibody pour - ABIN1305040 : Perez-Gonzalez, Albrecht, Blasi, Llobet: Schwann cells modulate short-term plasticity of cholinergic autaptic synapses. dans The Journal of physiology 2008 (PubMed)
    Show all 6 Pubmed References

  3. Rat (Rattus) Polyclonal SLC18A3 Primary Antibody pour IHC, WB - ABIN1742304 : Gallart-Palau, Tarabal, Casanovas, Sábado, Correa, Hereu, Piedrafita, Calderó, Esquerda: Neuregulin-1 is concentrated in the postsynaptic subsurface cistern of C-bouton inputs to α-motoneurons and altered during motoneuron diseases. dans FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2014 (PubMed)
    Show all 4 Pubmed References

  4. Human Polyclonal SLC18A3 Primary Antibody pour ICC, IF - ABIN4250912 : Li, Yu, Liu, Huang, Abumaria, Zhu, Huang, Xiong, Ren, Liu, Chui, Liu: Elevation of brain magnesium prevents and reverses cognitive deficits and synaptic loss in Alzheimer's disease mouse model. dans The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal SLC18A3 Primary Antibody pour IHC - ABIN926164 : Schmidt, Xie, Lyte, Vulchanova, Brown: Autonomic neurotransmitters modulate immunoglobulin A secretion in porcine colonic mucosa. dans Journal of neuroimmunology 2007 (PubMed)

Plus d’anticorps contre Solute Carrier Family 18 (Vesicular Acetylcholine), Member 3 partenaires d’interaction

Fruit Fly (Drosophila melanogaster) Solute Carrier Family 18 (Vesicular Acetylcholine), Member 3 (SLC18A3) interaction partners

  1. Reduction of the polyQ region, by one glutamine residue (13Q to 12Q), results in a significant increase in both amplitude and frequency of spontaneous cholinergic miniature EPSCs (mEPSCs) recorded in the aCC and RP2 motoneurons; and results in evoked synaptic currents that show increased duration: consistent with increased ACh release.

Human Solute Carrier Family 18 (Vesicular Acetylcholine), Member 3 (SLC18A3) interaction partners

  1. There is a distinctive pattern of human neocortical VChAT expression. The patterns of thalamic and cerebellar cortical cholinergic terminal distribution are likely unique to humans

  2. The results of this study suggest that the Gly360Arg mutant VAChT protein undergoes posttranslational degradation.

  3. PCMC expression of ADAM29, FLRT2, and SLC18A3 could be assessed as part of a routine screen to help identify individuals at risk of severe Obstructive sleep apnea in Asian populations

  4. Expression of VAChT is increased in neuronal cell lines following upregulation of Lhx8.

  5. alpha-Synuclein expression in axons to the distal gut correlates closely with expression of the cholinergic marker, VAChT.

  6. Data indicate that siRNA-mediated attenuation of vesicular acetylcholine transporter (VAChT, SLC18A3) reversed the apoptotic activity of vesamicol.

  7. Multiple abnormalities with intellectual and developmental disability result from recurrent deletions and reciprocal duplications of 10q11.21q11.23 including CHAT and SLC18A3.

  8. overexpressed ChAT enhanced transcription of the CHT1 gene but not the VACHT gene

  9. Mutations in the vesicular acetylcholine transporter demonstrate decreased affinity for acetylcholine and vesamicol.

  10. The colocalisation of CHT1 immunoreactivity with VAChT immunoreactivity in cholinergic enteric nerves in the human bowel thus suggests that CHT1 represents another marker of cholinergic nerves.

  11. Three non-coding SNPs were detected in SLC18A3. None demonstrated any reproducible association with late-onset AD in our samples.

  12. An 11.2 kb transgene (named hV11.2) that spanned about 5 kb upstream of the start of VACHT translation down to the first choline acetyltransferase coding exon gave variable expression in the medial habenular nucleus of transgenic mice

  13. presence of VAChT in cutaneous nerves and in both epidermal melanocytes and keratinocytes as well as in their nuclei

  14. Time-dependent dissociation of bound [3H]vesamicol is biphasic, but equilibrium saturation curves are not. The contrasting phasicity suggests that the pathway to and from the [3H]vesamicol binding site exists in open and at least partially closed states.

Mouse (Murine) Solute Carrier Family 18 (Vesicular Acetylcholine), Member 3 (SLC18A3) interaction partners

  1. Aged VAChT-deficient mice showed a decrease in the number of hippocampal neurons and Alzheimer's-Like Pathology.

  2. These findings suggest that nitrosylation of VAChT and VGLUT1 may be associated with dysfunctional acetylcholinergic and glutamatergic neurotransmission in Alzheimer's disease.

  3. Studied object recognition and spatial location in mice deficient for Vesicular Acetylcholine Transporter (VAChT) within interneurons of the striatum, found: impairment in home cage object recognition with a 15 min retention delay, but not with a 3 h retention delay; no on memory for the location of objects; sex differences in retention

  4. VAChT overexpression increases acetylcholine at the synaptic cleft and accelerates aging of neuromuscular junctions. Data demonstrate that increasing levels of acetylcholine at the synaptic cleft promote degeneration of adult neuromuscular junction, contributing to age- and disease-related motor deficits.

  5. Old VAChT deficient mice (13-16 months-old) showed more pronounced motor learning/balance deficits on the rotarod, and more pronounced balance deficits on the catwalk

  6. These results suggest that the VAChT-Cre lines are Cre-drivers that have selectivity in S and FR motor neurons.

  7. Loss of VAChT expression is associated with pulmonary inflammation.

  8. decreased VAChT levels affect synaptic vesicle biogenesis and distribution whereas a lower ACh content affects vesicles shape.

  9. we conclude that VAChT overexpression is sufficient to enhance ACh release in the hippocampal formation

  10. Data indicate that elimination of VAChT had only marginal consequences in striatum-related tasks and did not affect spontaneous locomotion, cocaine-induced hyperactivity, or its reward properties.

  11. Mice with 65% knockdown of VAChT had normal prepulse inhibition and short-term habituation of startle reaction, whereas long-term habituation was disrupted.

  12. VAChT mutant mice present preserved neuromuscular function, but altered brain cholinergic function and are hyperactive.

  13. These results reveal the dependence of short-term plasticity on the level of VAChT expression and efficient synaptic vesicle filling.

  14. Results indicated that VAChT mutant mice have profound cardiac remodeling and reactivation of the fetal gene program.

  15. Residues 481-490 contain trafficking information necessary for VAChT localization, and within this region L485 and L486 are strictly necessary. Clathrin-mediated endocytosis is required for targeting to microvesicles.

  16. Real-time RT-PCR revealed significant decreases in VAChT mRNA in the lung of sensitized and allergen challenged animals.

  17. Vesicular acetylcholine transporter-immunoreactive axon terminals enriched in the pontine nuclei of the mouse.

  18. Nerve fibers surrounding or within taste buds were immunoreactive for the VAChT antibody.

  19. results suggest that in rodent prefrontal cortex, the alpha7nAChR plays a major role in modulation of the postsynaptic excitation in spiny dendrites in contact with vesicular acetylcholine transporter containing axons

  20. VAChT is essential to the normal development of motor neurons and the release of acetylcholine

Solute Carrier Family 18 (Vesicular Acetylcholine), Member 3 (SLC18A3) profil antigène

Profil protéine

This gene is a member of the vesicular amine transporter family. The encoded transmembrane protein transports acetylcholine into secretory vesicles for release into the extracellular space. Acetylcholine transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene.

Gene names and symbols associated with SLC18A3

  • Vesicular acetylcholine transporter (VAChT) anticorps
  • solute carrier family 18 member A3 (SLC18A3) anticorps
  • solute carrier family 18 (vesicular acetylcholine transporter), member 3 (slc18a3) anticorps
  • solute carrier family 18 member A3 (Slc18a3) anticorps
  • solute carrier family 18 (vesicular acetylcholine transporter), member 3b (slc18a3b) anticorps
  • solute carrier family 18 (vesicular monoamine), member 3 (Slc18a3) anticorps
  • CG12345 anticorps
  • CG32848 anticorps
  • CT41182 anticorps
  • Dmel\\CG32848 anticorps
  • MGC64220 anticorps
  • rVAT anticorps
  • Slc18a3 anticorps
  • VAChT anticorps
  • VAT anticorps

Protein level used designations for SLC18A3

CG32848-PA , VAChT-PA , vesicular acetylcholine transporter , solute carrier family 18 (vesicular acetylcholine), member 3 , vesicular acetylcholine transporter-like , solute carrier family 18 (vesicular monoamine) member 3 , solute carrier family 18, member 3 , solute carrier family 18 member 3

GENE ID SPECIES
42795 Drosophila melanogaster
466071 Pan troglodytes
486774 Canis lupus familiaris
710053 Macaca mulatta
780320 Xenopus (Silurana) tropicalis
785833 Bos taurus
100473979 Ailuropoda melanoleuca
60422 Rattus norvegicus
6572 Homo sapiens
394082 Danio rerio
20508 Mus musculus
Fournisseurs de qualité sélectionnés pour anti-Solute Carrier Family 18 (Vesicular Acetylcholine), Member 3 (SLC18A3) Anticorps
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