Syndecan Binding Protein (Syntenin) Protéines (SDCBP)

The protein encoded by SDCBP was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. De plus, nous expédions SDCBP Anticorps (127) et SDCBP Kits (15) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
SDCBP 6386 O00560
SDCBP 53378 O08992
SDCBP 83841 Q9JI92
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Top SDCBP Protéines sur anticorps-enligne.fr

Showing 10 out of 17 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Escherichia coli (E. coli) Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 30 to 35 Days
$5,370.21
Détails
Escherichia coli (E. coli) Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 30 to 35 Days
$5,370.21
Détails
Escherichia coli (E. coli) Humain His tag   50 μg Connectez-vous pour afficher 4 Days
$352.00
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher Disponible
$814.00
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
Détails
Escherichia coli (E. coli) Humain His tag 100 μg Connectez-vous pour afficher 15 to 19 Days
$400.00
Détails
Levure Rat His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,794.00
Détails
Escherichia coli (E. coli) Souris His tag   50 μg Connectez-vous pour afficher 4 Days
$590.43
Détails
Escherichia coli (E. coli) Humain T7 tag,His tag 100 μg Connectez-vous pour afficher 15 to 18 Days
$682.00
Détails
Escherichia coli (E. coli) Humain His tag   10 μg Connectez-vous pour afficher 15 to 16 Days
$212.50
Détails

SDCBP Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , ,
, , ,
Mouse (Murine)

Rat (Rattus)

Plus protéines pour Syndecan Binding Protein (Syntenin) (SDCBP) partenaires d'interaction

Human Syndecan Binding Protein (Syntenin) (SDCBP) interaction partners

  1. Studied role of melanoma differentiation associated protein-9 (MDA-9)/Syntenin in autophagy of anoikis-resistant glioma stem cells.

  2. Frizzled 7 and phosphatidylinositol 4,5-diphosphate binding by syntenin PDZ2 domain supports Frizzled 7 trafficking and signaling.

  3. Syntenin mediates SRC function in exosomal cell-to-cell communication.

  4. These findings demonstrate that syntenin promotes VEGF signaling and, through its PDZ-dependent interaction with ephrin-B2, enhances VEGF-mediated VEGFR2 endocytosis and subsequent downstream signaling and angiogenesis in endothelial cells

  5. Syntenin-1 promotes invasion and progression of squamous cell carcinomas of the head and neck.

  6. MDA-9 upregulated active levels of known modulators of epithelial mesenchymal transformation, the small GTPases RhoA and Cdc42, via TGFbeta1, promoting lung metastasis of breast cancer cells.

  7. a unique function of MDA-9 as a facilitator and determinant of glioma stemness and survival.

  8. SDCBP might be an important marker for identifying Triple negative breast cancer cases that are suitable for dasatinib therapy.

  9. ACTB, CDKN1B, GAPDH, GRB2, RHOA and SDCBP are potent reference genes in neuroendocrine tumors of the lung.

  10. In summary, the study identifies miR-216b as a regulator of SDCBP expression in breast cancer which can potentially be targeted for developing newer therapies for the effective treatment of this killer disease.

  11. Data show that patients with high MDA-9/Syntenin and high Slug expressions were associated with poor overall survival compared to those with low expression in lung adenocarcinomas.

  12. Data suggest that syntenin/SDCBP PDZ domains 1 and 2 recognize a broad range of peptide ligands with preferences for nectin-1, hydrophobic amino acid motifs, and cryptic internal ligands/peptide fragments.

  13. these findings demonstrate that syntenin may act as an important positive regulator of TGF-b signaling by regulating caveolin-1-mediated internalization of TbRI; thus, providing a novel function for syntenin that is linked to cancer progression.

  14. To predict mda-9's association with extracellular matrix organization.

  15. MDA-9, co-expressed with GRP78, as a melanoma protein associated with lymph node metastasis. Investigating how MDA-9 and GRP78 interact to contribute to melanoma metastasis and disease progression could reveal new potential avenues of targeted therapy

  16. Syntenin-ALIX exosome biogenesis and budding into multivesicular bodies are controlled by ARF6 and PLD2.

  17. High MDA-9 expresison is associated with glioma.

  18. ALCAM stably interacts with actin by binding to syntenin-1 and ezrin.

  19. Our findings indicate that MDA-9/Syntenin might provide an attractive target for developing detection, monitoring, and therapeutic strategies for managing Urothelial cell carcinoma .

  20. Results suggested that SDCBP played an important role in tumor growth of ER-negative breast cancers.

Mouse (Murine) Syndecan Binding Protein (Syntenin) (SDCBP) interaction partners

  1. These findings demonstrate that syntenin promotes VEGF signaling and, through its PDZ-dependent interaction with ephrin-B2, enhances VEGF-mediated VEGFR2 endocytosis and subsequent downstream signaling and angiogenesis in endothelial cells

  2. Present study is the first demonstration of the relevance of MDA-9/Syntenin expression in regulating inflammation and immunosuppression in the microenvironment thereby impacting tumor growth and metastasis in mouse melanoma model.

  3. Syntenin-1 negatively regulates the intestinal immunoglobulin production and has a function to maintain the intestinal homeostasis in vivo.

  4. ALCAM stably interacts with actin by binding to syntenin-1 and ezrin.

  5. Angiopoietin-2 secretion by endothelial cell exosomes: regulation by the phosphatidylinositol 3-kinase (PI3K)/Akt/endothelial nitric oxide synthase (eNOS) and syndecan-4/syntenin pathways.

  6. MDA-9/syntenin may play a prominent role during normal mouse development in the context of cell proliferation as well as differentiation through modulating multiple signaling pathways as a crucial adaptor protein.

  7. Complex of Unc51.1/SynGAP1/Syntenin governs axon formation via Ras-like GTPase signaling and through regulation of the Rab5-mediated endocytic pathways within developing axons

  8. Syntenin-1 may function as a scaffolding protein coupling CD6 and other lymphocyte receptors to cytoskeleton and/or signaling effectors during immunologic synapse maturation

  9. syntenin plays a role in the migration of oligodendroglial precursors, and we suggest that NG2-syntenin-1 interactions contribute to this

Profil protéine SDCBP

Profil protéine

The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with SDCBP

  • syndecan binding protein (SDCBP)
  • syndecan binding protein (Sdcbp)
  • syndecan binding protein L homeolog (sdcbp.L)
  • syndecan binding protein (LOC732879)
  • syndecan binding protein (syntenin) (sdcbp)
  • mda-9 Protéine
  • MGC81274 Protéine
  • sb:eu862 Protéine
  • si:dkey-235k4.1 Protéine
  • st1 Protéine
  • sycl Protéine
  • syntenin Protéine
  • syntenin-1 Protéine
  • tacip18 Protéine

Protein level used designations for SDCBP

melanoma differentiation associated protein-9 , melanoma differentiation-associated protein 9 , pro-TGF-alpha cytoplasmic domain-interacting protein 18 , scaffold protein Pbp1 , syndecan-binding protein 1 , syntenin-1 , syndecan interacting protein , syntenin , syndecan binding protein , syntenin-b

GENE ID SPECIES
6386 Homo sapiens
53378 Mus musculus
83841 Rattus norvegicus
421136 Gallus gallus
447442 Xenopus laevis
732879 Bombyx mori
482977 Canis lupus familiaris
510979 Bos taurus
100151838 Sus scrofa
100721404 Cavia porcellus
407719 Danio rerio
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