T Cell Immunoglobulin and Mucin Domain Containing 2 Protéines (TIMD2)

Probable receptor for SEMA4A involved in the regulation of T-cell function. De plus, nous expédions TIMD2 Anticorps (28) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
TIMD2 171284 Q8R183
TIMD2 287222 Q5FVR0
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Top TIMD2 Protéines sur anticorps-enligne.fr

Showing 4 out of 5 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Souris rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Connectez-vous pour afficher 50 to 55 Days
$5,355.45
Détails
Levure Rat His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,656.50
Détails
CHO Cells Souris Fc Tag   100 μg Connectez-vous pour afficher 5 to 8 Days
$546.25
Détails
HEK-293 Cells Souris Fc Tag   100 μg Connectez-vous pour afficher 5 to 8 Days
$546.25
Détails

TIMD2 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Mouse (Murine) , ,
, ,
Rat (Rattus)

Plus protéines pour T Cell Immunoglobulin and Mucin Domain Containing 2 (TIMD2) partenaires d'interaction

Mouse (Murine) T Cell Immunoglobulin and Mucin Domain Containing 2 (TIMD2) interaction partners

  1. We concluded that pro-apoptotic effects on Th1 (Montrer HAND1 Protéines) population through galectin-9 (Montrer LGALS9 Protéines)-Tim-3 (Montrer HAVCR2 Protéines) pathway and the up-regulation of Tim-2 on Th2 cells might be critical to Th2-biased response of host with schistosomiasis japonica.

  2. TIM-2 signaling influences both proliferation and antibody production of B cells during the early phase of collagen-induced arthritis

  3. TIM-2 can function as an iron uptake pathway.

  4. The increased expression of the pro-inflammatory and proapoptotic genes, a higher number of apoptotic cells, and increased injury and mortality of the TIM2-deficient mice suggest a protective role of TIM2 in cisplatin-induced nephrotoxicity.

  5. TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis.

  6. expression of TIM-2 significantly impairs the induction of NFAT (Montrer NFATC1 Protéines) and AP-1 (Montrer JUN Protéines) transcriptional reporters

  7. The mTIM-1 structure identified a homophilic TIM-TIM adhesion interaction, whereas the mTIM-2 domain formed a dimer that prevented homophilic binding.

  8. There are Tim2-binding molecules on hepatocytes. Tim2-hFc inhibited differentiation & proliferation of hepatocytes in fetal liver primary culture. Down-regulation of Tim2 expression by siRNA enhanced expression of liver differentiation marker genes.

  9. Tim-2 negatively regulates the Th2 differentiation of Ag-primed T-cells and the development of EC during the effector phase.

Profil protéine TIMD2

Profil protéine

Probable receptor for SEMA4A involved in the regulation of T-cell function. The interaction with SEMA4A enhances T-cell activation (By similarity).

Gene names and symbols associated with TIMD2

  • T cell immunoglobulin and mucin domain containing 2 (Timd2)
  • T-cell immunoglobulin and mucin domain containing 2 (Timd2)
  • AA816106 Protéine
  • AU019358 Protéine
  • AU019662 Protéine
  • C78111 Protéine
  • G9D3 Protéine
  • TIM-2 Protéine
  • Tim2 Protéine

Protein level used designations for TIMD2

T-cell immunoglobulin and mucin domain containing 2 , T-cell immunoglobulin and mucin domain-containing protein 2 , T-cell membrane protein 2 , TIMD-2 , TIM-2

GENE ID SPECIES
171284 Mus musculus
287222 Rattus norvegicus
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