Transmembrane Protein 59 Protéines (TMEM59)

Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. De plus, nous expédions TMEM59 Anticorps (34) et et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
Rat TMEM59 TMEM59 100196907  
TMEM59 9528 Q9BXS4
TMEM59 56374 Q9QY73
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Showing 6 out of 8 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Souris rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Connectez-vous pour afficher 50 to 55 Days
$5,355.45
Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,869.04
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher Disponible
$814.00
Détails
Wheat germ Humain GST tag 2 μg Connectez-vous pour afficher 11 to 12 Days
$338.33
Détails
Levure Orang-Utan His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,495.17
Détails
Levure Cynomolgus His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,495.17
Détails

TMEM59 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , ,
, , ,
Mouse (Murine)
,

Plus protéines pour Transmembrane Protein 59 (TMEM59) partenaires d'interaction

Human Transmembrane Protein 59 (TMEM59) interaction partners

  1. identify the single-span membrane protein TMEM59 as an interactor of FZD and LRP6 (Montrer LRP6 Protéines) and a positive regulator of Wnt (Montrer WNT2 Protéines) signaling. Mechanistically, TMEM59 promotes the formation of multimeric Wnt (Montrer WNT2 Protéines)-FZD assemblies via intramembrane interactions.

  2. The TMEM59 gene identified from our discovery approach was recently implicated in amyloid-beta protein precursor post-translational processing, supporting a role for epigenetic change in LOAD pathology.

  3. TMEM59 affects amyloid precursor protein (Montrer APP Protéines) shedding by reducing its acccess to cellular components.

Mouse (Murine) Transmembrane Protein 59 (TMEM59) interaction partners

  1. The results of this study revealed that DCF1-KO mice presented a visual behavioral deficit, higher GAD67 (Montrer GAD1 Protéines) levels, and lower electrophysiological activity in V1 via the GABA system.

  2. Notably, we observed a significant increase in the ATP concentration in Dcf1(-/-) mice, suggesting a greater demand for energy in the absence of Dcf1. We studied the relationship between Dcf1 and NPY (Montrer NPY Protéines) and revealed that Dcf1 plays a critical role in energy balance.

  3. MicroRNA-351 regulates TMEM 59 (DCF1) expression and mediates neural stem cell morphogenesis.

  4. The expression of tmem59 is an important factor contributing to Alzheimer's disease.

Pig (Porcine) Transmembrane Protein 59 (TMEM59) interaction partners

  1. Chromosome mapping of 3 proteins (CRSP9 (Montrer MED7 Protéines), ETF1 (Montrer ETF1 Protéines) and TMEM59) in swine

Profil protéine TMEM59

Profil protéine

Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. Inhibits APP transport to the cell surface and further shedding (By similarity).

Gene names and symbols associated with TMEM59

  • transmembrane protein 59 (tmem59)
  • transmembrane protein 59 (Tmem59)
  • transmembrane protein 59 (TMEM59)
  • 1110001M20Rik Protéine
  • 3110046P06Rik Protéine
  • AI256529 Protéine
  • C1orf8 Protéine
  • D4Ertd20e Protéine
  • HSPC001 Protéine
  • MTDCF1 Protéine
  • ORF18 Protéine
  • Tmem59 Protéine

Protein level used designations for TMEM59

transmembrane protein 59 , liver membrane-bound protein , thymic dendritic cell-derived factor 1

GENE ID SPECIES
566384 Danio rerio
100196907 Rattus norvegicus
9528 Homo sapiens
56374 Mus musculus
509775 Bos taurus
733610 Sus scrofa
479561 Canis lupus familiaris
100173202 Pongo abelii
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