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CD300LB is a nonclassical activating receptor of the immunoglobulin (Ig) superfamily expressed on myeloid cells (Martinez-Barriocanal and Sayos, 2006 [PubMed 16920917]).[supplied by OMIM, Mar 2008]..
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this study shows that that Trem5 (Montrer CD300E Protéines) is up-regulated in response to viral RNA to regulate myeloid cell activation
C. jejuni interacted preferentially with LMIR5.
LMIR5 extracellular domain is new inflammatory mediator and endogenous ligand of TLR4 (Montrer TLR4 Protéines).
neutrophil-derived soluble LMIR5 amplifies lipopolysaccharide-induced lethal inflammation.
TIM1 (Montrer ARHGEF5 Protéines) is an endogenous ligand for LMIR5.
although both mouse and human LMIR5 play activatory roles in innate immunity cells, the functions of LMIR5 were differentially regulated in mouse versus human cells.
this paper identified CD300b as an lipopolysaccharide-recognizing receptor that regulated TLR4 (Montrer TLR4 Protéines) signaling
CD300LB expression is significantly upregulated in human masticatory mucosa during wound healing
CD300 molecules are all expressed by DC; CD300b, d, e and f are restricted to different subpopulations of the myeloid DC lineage. They have been shown to regulate DC function both in vitro and in vivo.
CD300b defines a nonclassical Ig receptor able to trigger signals by coupling distinct mediators and thus initiating different signaling pathways
CD300LB is a nonclassical activating receptor of the immunoglobulin (Ig) superfamily expressed on myeloid cells (Martinez-Barriocanal and Sayos, 2006
CD300 antigen-like family member B
, CMRF-35-like molecule-7
, CMRF35-like molecule 7
, immune receptor expressed on myeloid cells 3
, leukocyte mono-Ig-like receptor 5
, CD300 antigen like family member B
, triggering receptor expressed on myeloid cells 5