Triggering Receptor Expressed On Myeloid Cells-Like 1 Protéines (TREML1)

TREML1 encodes a member of the triggering receptor expressed on myeloid cells-like (TREM) family.

afficher tous les protéines Gène GeneID UniProt
Humain TREML1 TREML1 340205 Q86YW5
Souris TREML1 TREML1 71326 Q8K558
Rat TREML1 TREML1 501096  
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Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Human Cells Humain His tag 100 μg Connectez-vous pour afficher 20 to 21 Days
$382.80
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Escherichia coli (E. coli) Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 30 to 35 Days
$4,744.22
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Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$5,960.83
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Cellules d'insectes Souris rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Connectez-vous pour afficher 50 to 55 Days
$4,649.05
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Mammalian Cells Humain His tag   50 μg Connectez-vous pour afficher 4 Days
$269.50
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HEK-293 Cells Humain His tag Validation with Western Blot 10 μg Connectez-vous pour afficher 8 to 11 Days
$504.90
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Human Humain His tag   10 μg Connectez-vous pour afficher 15 to 16 Days
$175.00
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Plus protéines pour Triggering Receptor Expressed On Myeloid Cells-Like 1 (TREML1) partenaires d'interaction

Human Triggering Receptor Expressed On Myeloid Cells-Like 1 (TREML1) interaction partners

  1. Study characterized the expression of TREM genes in cerebellum and temporal cortex and determined TREML1 and TREM2 (Montrer TREM2 Protéines) to be the only reliably expressed TREM genes in these brain regions; identified rs9357347 as a putative regulatory variant that is associated with protection from Alzheimer's disease and with increased TREML1 and TREM2 (Montrer TREM2 Protéines) brain levels.

  2. Platelet-derived soluble TLT-1 is a potent endogenous regulator of sepsis-associated inflammation.

  3. These results suggest that during inflammation, sTLT-1 may mediate hemostasis by enhancing actin polymerization, resulting in increased platelet aggregation and adherence to the endothelium.

  4. initial characterization of TREM-like transcript (TLT)-1 results indicate it is likely that TLT-1 regulates the signaling of the TREM family receptors(TLT-1)

  5. In contrast to previously characterized immunoreceptor tyrosine-based inhibition motif (ITIM) receptors, TLT1 enhances rather than inhibits calcium signaling in rat RBL-2H3 cells, a property dependent on the SHP-2 recruiting classical Tyr281 ITIM.

  6. A soluble fragment of the TLT-1 extracellular domain is found in serum of humans and mice and that an isoform of similar mass is released from platelets following activation with thrombin (Montrer F2 Protéines).

  7. Define a platelet specific function for TLT1 in regulation of aggregation.

  8. Phenotypic heterogeneity in the Gray platelet syndrome extends to the expression of TREM family member, TLT-1.

  9. TLT-1 plays a protective role during inflammation by dampening the inflammatory response and facilitating platelet aggregation at sites of vascular injury

Mouse (Murine) Triggering Receptor Expressed On Myeloid Cells-Like 1 (TREML1) interaction partners

  1. TLT (Montrer OTOP1 Protéines)-1s, alternative transcripts of triggering receptor expressed on myeloid cell-like transcript-1 (TLT-1), Inhibits the triggering receptor expressed on myeloid cell-2 (TREM-2 (Montrer TREM2 Protéines))-mediated signaling pathway during osteoclastogenesis.

  2. initial characterization of TREM-like transcript (TLT)-1; results indicate it is likely that TLT-1 regulates the signaling of the TREM family receptors

  3. A soluble fragment of the TLT-1 extracellular domain is found in serum of humans and mice and that an isoform of similar mass is released from platelets following activation with thrombin (Montrer F2 Protéines).

  4. TLT-1 plays a protective role during inflammation by dampening the inflammatory response and facilitating platelet aggregation at sites of vascular injury

Profil protéine Triggering Receptor Expressed On Myeloid Cells-Like 1 (TREML1)

Profil protéine

This gene encodes a member of the triggering receptor expressed on myeloid cells-like (TREM) family. The encoded protein is a type 1 single Ig domain orphan receptor localized to the alpha-granule membranes of platelets. The encoded protein is involved in platelet aggregation, inflammation, and cellular activation and has been linked to Gray platelet syndrome. Alternative splicing results in multiple transcript variants

Gene names and symbols associated with TREML1

  • triggering receptor expressed on myeloid cells 2 (LOC474898)
  • triggering receptor expressed on myeloid cells like 1 (TREML1)
  • triggering receptor expressed on myeloid cells-like 1 (Treml1)
  • 5430401J17Rik Protéine
  • dJ238O23.3 Protéine
  • GLTL1825 Protéine
  • PRO3438 Protéine
  • RGD1565175 Protéine
  • TLT-1 Protéine
  • TLT1 Protéine

Protein level used designations for TREML1

triggering receptor expressed on myeloid cells-like 1 , trem-like transcript-1-like , trem-like transcript 1 protein , triggering receptor expressed on myeloid cells-like protein 1 , triggering receptor expressed on myeloid cells-like 1c , triggering receptor expressed on myeloid cells-like 1d , triggering receptor expressed on myeloid cells-like 1e

GENE ID SPECIES
474898 Canis lupus familiaris
748461 Pan troglodytes
784711 Bos taurus
340205 Homo sapiens
71326 Mus musculus
501096 Rattus norvegicus
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