Profil protéine

Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins (By similarity).

Gene names and symbols associated with USP34

• ubiquitin specific peptidase 34 (Usp34) anticorps
• ubiquitin specific peptidase 34 (USP34) anticorps
• ubiquitin specific peptidase 34 (usp34) anticorps

• A530081C03Rik anticorps
• Murr2 anticorps

Protein level used designations for USP34

ubiquitin carboxyl-terminal hydrolase 34 , ubiquitin specific protease 34 , ubiquitin specific peptidase 34 , usp36 , ubiquitin specific peptidase 34-like , deubiquitinating enzyme 34 , ubiquitin thioesterase 34 , ubiquitin thiolesterase 34 , ubiquitin-specific-processing protease 34 , U2af1-rs1 region 2