CCL20 anticorps

N° du produit ABIN1043783

N° du produit (Fournisseur): 209-301-b51

L’anticorps Souris Monoclonal anti-CCL20 a été validé pour WB. Il convient pour détecter CCL20 dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour CCL20 anticorps (ABIN1043783)

Antigène: CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CCL20 est non-conjugé

Application: Western Blotting (WB)

Clone: 3N2D9

Détail du produit anti-CCL20 anticorps

N° du produit (Fournisseur): 209-301-b51

Fournisseur: Rockland

Fonction: MIP-3 alpha Antibody

Réactivité croisée (Details): This antibody is specific for human MIP-3α protein.

Attributs du produit: Synonyms: mouse anti-MIP-3 alpha Antibody, mouse anti-MIP-3a Antibody, MIP-3α , CCL20, C-C motif chemokine 20, small-inducible cytokine A20, macrophage inflammatory protein 3 alpha, MIP-3-alpha, liver and activation-regulated chemokine, CC chemokine LARC and beta chemokine exodus-1

Purification: Anti-MIP-3α was purified from clarified mouse ascetic fluid by Protein A chromatography followed by extensive dialysis against the buffer stated above.

Stérilité: Sterile filtered

Immunogène:

Immunogen: Anti-MIP-3alpha (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human MIP-3alpha produced in E.coli followed by hybridoma development.

Immunogen Type: Recombinant Protein

Isotype: IgG1

Information d'application

Indications d'application:

Application Note: Anti-Human MIP-3α antibody has been tested by western blot and is suitable for use in ELISA, IP, and Neutralization. Specific conditions for reactivity should be optimized by the end user.

Western Blot Dilution: 0.5 μg/mL

Other: User Optimized

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Références pour anticorps anti-CCL20 (ABIN1043783)

Lisignoli, Manferdini, Codeluppi, Piacentini, Grassi, Cattini, Filardo, Facchini: "CCL20/CCR6 chemokine/receptor expression in bone tissue from osteoarthritis and rheumatoid arthritis patients: different response of osteoblasts in the two groups." dans: Journal of cellular physiology, Vol. 221, Issue 1, pp. 154-60, (2009) (PubMed).

Détails sur CCL20

Antigène: CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))

Autre désignation: CCL20

Sujet: Background: MIP-3α (also known as C-C motif chemokine 20, small-inducible cytokine A20, macrophage inflammatory protein 3 alpha, MIP-3-alpha, liver and activation-regulated chemokine, CC chemokine LARC and beta chemokine exodus-1) is a chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. MIP-3α inhibits proliferation of myeloid progenitors in colony formation assays and may be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. MIP-3α also possesses antibacterial activity against E.coli and S.aureus. MIP-3α is a secreted protein that is expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels of expression are also seen in thymus, prostate, testis, small intestine and colon. C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.

ID gène: 6364, 4759076

UniProt: P78556

Pathways: Phosphorylation & l'infection par le SRAS-CoV-2