TNFSF4 anticorps (C-Term)

N° du produit ABIN1077446

Détail du produit anti-TNFSF4 anticorps

Antigène: TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp TNFSF4 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: At least two isoforms of TNFSF4 are known to exist, this antibody will detect both isoforms.

Purification: Affinity chromatography purified via peptide column

Immunogène: Rabbit polyclonal TNFSF4 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human TNFSF4.

Isotype: IgG

Information d'application

Indications d'application: TNFSF4 antibody can be used for detection of TNFSF4 by Western blot at 0.5 - 1 μg/mL.

Commentaires:

(CT) Tumor necrosis factor ligand superfamily 4

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C/-20 °C

Détails sur TNFSF4

Antigène: TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))

Autre désignation: TNFSF4 (TNFSF4 Produits)

Synonymes: anticorps TNFSF4, anticorps OX40L, anticorps TNFRSF4, anticorps CD134L, anticorps CD252, anticorps GP34, anticorps OX-40L, anticorps OX4OL, anticorps TXGP1, anticorps Ath-1, anticorps Ath1, anticorps Ox40l, anticorps Txgp1l, anticorps gp34, anticorps TNF superfamily member 4, anticorps tumor necrosis factor (ligand) superfamily, member 4, anticorps TNFSF4, anticorps Tnfsf4

Sujet: The tumor necrosis factor superfamily member TNFSF4 is a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells, such as dendritic cells and activated B-cells, and also on other cells such as vascular endothelial cells, mast cells, and natural killer cells. TNFSF4 signals specifically through the TNFRSF4 receptor, is expressed predominantly on CD4+T cells but also on certain activated CD8+T cells. TNFRSF4/TNFSF4 functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival, and increases expression of RANTES, IL-2, IL-3, and IFNgamma. TNFRSF4/TNFSF4 signaling plays an important role in immunotolerance.
Synonyms: Tumor necrosis factor ligand superfamily 4, OX40L, GP34, TXGP1, CD134L, CD252

Poids moléculaire: 20 kDa

ID gène: 7292

NCBI Accession: NP_003317

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation, Cancer Immune Checkpoints