ITGB1 anticorps

N° du produit ABIN1106229

Cet anticorps anti-ITGB1 est un anticorps Souris Monoclonal détectant ITGB1 dans WB, IHC (fro) et EIA. Adapté pour Humain.

Aperçu rapide pour ITGB1 anticorps (ABIN1106229)

Antigène: ITGB1 (Integrin beta 1 (ITGB1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ITGB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Clone: DF7

Détail du produit anti-ITGB1 anticorps

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Ig Fraction

Immunogène: Wheat germ agglutinin binding glycoproteins of Human fibroblasts. Hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, 0.09 % Sodium Azide, 1.0 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur ITGB1

Antigène: ITGB1 (Integrin beta 1 (ITGB1))

Autre désignation: CD29 / Integrin beta-1

Sujet: CD29 or the integrin beta-1 belongs to the family of cell adhesion receptors. It was initially characterized independently as protein gpIIa appearing on platelets, as the common beta subunit of the very late activation antigen (VLA), and as a component of various protein complexes binding to extracellular matrix proteins. The CD29 is expressed at the cell surface exclusively as part of a heterodimer, in association with one of at least nine different integrin alpha subunits (alpha 1, alpha 2, alpha 3, alpha 4, alpha 5, alpha 6, alpha 7, alpha 8, and alpha v). With the exception of red blood cells and possible weak expression on granulocytes, CD29 is expressed nearly all cell and tissue types. Monoclonal antibodies against this β1-Integrin subunit are applicable in paraffin-embedded and frozen sections, immunoblotting and immunoprecipitation. Numerous studies have shown that β1 -Integrins have a distinct and wide cellular distribution and that there are alterations in malignant cells in their beta-1 integrin expression.Synonyms: FNRB, Fibronectin receptor subunit beta, ITGB1, Integrin VLA-4 subunit beta, MDF2, MSK12

ID gène: 9606

UniProt: P05556

Pathways: Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome