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Desmoglein 3 anticorps
DSG3
Reactivité: Humain
WB, IF, IP, IHC (p), IHC (fro)
Hôte: Souris
Monoclonal
5G11
unconjugated
N° du produit ABIN1106983
Détail du produit anti-Desmoglein 3 anticorps
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Antigène
Voir toutes Desmoglein 3 (DSG3) Anticorps
Desmoglein 3 (DSG3)
Reactivité
Toutes les réactivités sur Desmoglein 3 Anticorps
Humain
Hôte
Toutes les hôtes sur Desmoglein 3 Anticorps
Souris
Clonalité
Toutes les clonalités sur Desmoglein 3 Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers Desmoglein 3 Anticorps
Cet anticorp Desmoglein 3 est non-conjugé
Application
Tous les applications à travers Desmoglein 3 Anticorps.
Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
Specificité
The monoclonal antibody 5G11 reacts with the 140 kDa desmoglein 3 protein. Furthermore it is not cross reactive with desmoglein 1 or desmoglein 2.
Réactivité croisée (Details)
Species reactivity (tested):Human
Purification
Protein G
Clone
5G11
Isotype
IgG1
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
0.1 mg/mL
Buffer
PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
Stock
4 °C/-20 °C
Stockage commentaire
Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Détails sur Desmoglein 3
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Antigène
Desmoglein 3 (DSG3)
Autre désignation
Desmoglein-3 (DSG3 Produits )
Synonymes
anticorps DSG3, anticorps CDHF6, anticorps PVA, anticorps bal, anticorps balding, anticorps desmoglein 3, anticorps DSG3, anticorps Dsg3
Sujet
Desmoglein 3 is a member of the desmosomal cadherin family that comprise the desmogleins and desmocollins. Desmosomes are cell-cell junctions in most epithelial cells and serve to link the intermediate filament cytoskeletons of adjacent cells. Within the desmosome the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 3 is synthesized in both the basal and the lower suprabasal compartments.Synonyms: 130 kDa pemphigus vulgaris antigen, CDHF6, Cadherin family member 6, DSG3, PVA
ID gène
1830
NCBI Accession
NP_001935
UniProt
P32926
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