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Desmoglein 3 anticorps

DSG3 Reactivité: Humain WB, IF, IP, IHC (p), IHC (fro) Hôte: Souris Monoclonal 5G11 unconjugated
N° du produit ABIN1106983
  • Antigène Voir toutes Desmoglein 3 (DSG3) Anticorps
    Desmoglein 3 (DSG3)
    Reactivité
    • 67
    • 21
    • 16
    Humain
    Hôte
    • 61
    • 26
    Souris
    Clonalité
    • 60
    • 27
    Monoclonal
    Conjugué
    • 36
    • 9
    • 8
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Desmoglein 3 est non-conjugé
    Application
    • 64
    • 35
    • 20
    • 18
    • 16
    • 13
    • 13
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificité
    The monoclonal antibody 5G11 reacts with the 140 kDa desmoglein 3 protein. Furthermore it is not cross reactive with desmoglein 1 or desmoglein 2.
    Réactivité croisée (Details)
    Species reactivity (tested):Human
    Purification
    Protein G
    Clone
    5G11
    Isotype
    IgG1
    Top Product
    Discover our top product DSG3 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    Desmoglein 3 (DSG3)
    Autre désignation
    Desmoglein-3 (DSG3 Produits)
    Synonymes
    anticorps DSG3, anticorps CDHF6, anticorps PVA, anticorps bal, anticorps balding, anticorps desmoglein 3, anticorps DSG3, anticorps Dsg3
    Sujet
    Desmoglein 3 is a member of the desmosomal cadherin family that comprise the desmogleins and desmocollins. Desmosomes are cell-cell junctions in most epithelial cells and serve to link the intermediate filament cytoskeletons of adjacent cells. Within the desmosome the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 3 is synthesized in both the basal and the lower suprabasal compartments.Synonyms: 130 kDa pemphigus vulgaris antigen, CDHF6, Cadherin family member 6, DSG3, PVA
    ID gène
    1830
    NCBI Accession
    NP_001935
    UniProt
    P32926
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