Dopamine Receptor d1 anticorps (C-Term)
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- Antigène Voir toutes Dopamine Receptor d1 (DRD1) Anticorps
- Dopamine Receptor d1 (DRD1) (Dopamine Receptor D1 (DRD1))
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Épitope
- C-Term
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Dopamine Receptor d1 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- This antibody detects Dopamine D1 Receptor at C-term.
- Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse, rat
- Purification
- Immunogen affinity purified
- Immunogène
- A synthetic peptide corresponding to a sequence at the C-terminal of human DRD1 .Remarks: Sequence is identical to the related rat and mouse sequence.
- Isotype
- IgG
- Top Product
- Discover our top product DRD1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Reconstitution
- 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Buffer
- 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
- Agent conservateur
- Sodium azide, Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Antigène
- Dopamine Receptor d1 (DRD1) (Dopamine Receptor D1 (DRD1))
- Autre désignation
- Dopamine D1 Receptor (DRD1 Produits)
- Synonymes
- anticorps DRD1, anticorps Dop1, anticorps D1A, anticorps DADR, anticorps DRD1A, anticorps drd1, anticorps C030036C15Rik, anticorps Drd-1, anticorps Drd1, anticorps Gpcr15, anticorps D1a, anticorps Drd1a, anticorps dopamine receptor D1, anticorps dopamine receptor, D1, anticorps dopamine receptor D1b, anticorps DRD1, anticorps Dop1, anticorps drd1b, anticorps Drd1
- Sujet
- Dopamine receptor D1, also known as DRD1, is a human gene. It is the most highly expressed DA receptor subtype among the DA receptor family. Receptors for dopamine have been classified into two functional types, D1 and D2. They belong to the family of receptors acting through G (or guaninenucleotide-binding) proteins. D2 receptors inhibit adenylyl cyclase, but D1 receptors stimulate adenylyl cyclase and activate cyclic AMP-dependent protein kinases. Dopamine D1 and D2 receptors are targets of drug therapy in many psychomotor disorders, including Parkinson's disease and schizophrenia, and may also have a role in drug addiction and alcoholism. D1 receptors regulate neuron growth and differentiation, influence behaviour and modify dopamine D2 receptor-mediated events. And the presence of a D1 receptor gene restriction fragment length polymorphism will be helpful for future disease linkage studies. DRD1 also regulates the neurochemical architecture of the striatum and is critical for the normal expression of motor activity.Synonyms: D(1A) dopamine receptor, DRD1
- ID gène
- 1812
- NCBI Accession
- NP_000785
- UniProt
- P21728
- Pathways
- cAMP Metabolic Process, Inositol Metabolic Process, Protein targeting to Nucleus, Feeding Behaviour, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
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