CCL2 anticorps
Aperçu rapide pour CCL2 anticorps (ABIN1108184)
Antigène
Voir toutes CCL2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Réactivité croisée (Details)
- Species reactivity (tested):Mouse.
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0,1 mg/mL
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Buffer
- PBS, 0,1 % BSA
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
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Autre désignation
- MCP1 / CCL2
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Sujet
- Monocyte chemotactic protein-1 (MCP-1) belong to the b or CC family of chemotactic cytokines, or chemokines, which stimulate the migration of monocytic cells. In contrast, the CXC chemokines predominantly activate polymorphonuclear leukocytes. The coordinated synthesis and release of MCP-1 plays a central role in both acute and chronic inflammatory processes by controlling the influx of phagocytic cells. Furthermore, their state of activation is in concert with primary inflammatory cytokines, such as interleukin-1 (IL-1), tumor necrosis factor-alpha (TNF-a), and IL-6. A selective accumulation of MCP-1 in the cerebrospinal fluid (CSF) of AIDS patients with cytomegalovirus (CMV) encephalitis, but not with other opportunistic infections (OI) or primary lymphomas of the central nervous system (CNS), has been described.Synonyms: C-C motif chemokine 2, HC-11, HC11, MCAF, MCP-1, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, Monocyte chemotactic protein 1, Monocyte secretory protein JE, SCYA2, Small-inducible cytokine A2
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ID gène
- 10090
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UniProt
- P10148
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, Phosphorylation & l'infection par le SRAS-CoV-2
Antigène
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