MORG1 anticorps (N-Term)

N° du produit ABIN1108280

Détail du produit anti-MORG1 anticorps

Antigène: MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))

Épitope: N-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MORG1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificité: This antibody MORG1 detects (N-term). No cross reactivity with other proteins.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Immunogen affinity purified

Immunogène: Synthetic peptide corresponding to a sequence near the N-terminal of human MORG1 .Remarks: Sequence is identical to the related mouse and rat sequence.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur MORG1

Antigène: MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))

Autre désignation: MORG1 (wdr83 Produits)

Synonymes: anticorps MORG1, anticorps 1500041N16Rik, anticorps Morg1, anticorps RGD1306947, anticorps morg1, anticorps MAPK organizer 1, anticorps wu:fj29g04, anticorps zgc:92654, anticorps WD repeat domain 83, anticorps WD repeat domain containing 83, anticorps WD repeat domain 83 L homeolog, anticorps WDR83, anticorps Wdr83, anticorps wdr83.L, anticorps wdr83

Sujet: MORG1 (mitogen-activated protein kinase organizer 1), a member of the WD-40 protein family that was isolated as a binding partner of the extracellular signal-regulated kinase (ERK) pathway scaffold protein MP1. MORG1 specifically associates with several components of the ERK pathway, including MP1, Raf-1, MEK, and ERK, and stabilizes their assembly into an oligomeric complex. MORG1 facilitates ERK activation when cells are stimulated with lysophosphatidic acid, phorbol 12-myristate 13-acetate,or serum, but not in response to epidermal growth factor. Suppression of MORG1 by short interfering RNA leads to a marked reduction in ERK activity when cells are stimulated with serum. MORG1 is a component of a modular scaffold system that participates in the regulation of agonist-specific ERK signaling.Synonyms: MAPK organizer 1, MGC4238, Mitogen-activated protein kinase organizer 1

ID gène: 84292

NCBI Accession: NP_001093207

UniProt: Q9BRX9