POP7 anticorps

N° du produit ABIN1108698

Détail du produit anti-POP7 anticorps

Antigène: POP7 (Processing of Precursor 7, Ribonuclease P/MRP Subunit (POP7))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp POP7 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: Specificity has been tested in ELISA. In immunoblotting, under less stringent washing conditions, a weaker band of approximately 60 kDa is also detected (Figure 1, Right Panel). Additional tests for cross reactivity have not yet been performed.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Purified

Immunogène: Recombinant GST-hRPP20 (NCBI accession number AAC24113, expression vector pGEC-2T), expressed in E.coli.

Clone: 1F11

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Dissolve in 200 μL buffer for a 0.5 mg/mL antibody concentration in 1 % BSA

Concentration: 0.5 mg/mL (when dissolved at 0.5 mg/mL, the BSA concentration will be 1%)

Buffer: 10 mM Ammonium Bicarbonate buffer, 2 mg BSA

Précaution d'utilisation: Be careful opening the vial since the antibody resides in a Vacuum.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C or Add up to 0.05% Sodium Azide for long term storage.

Détails sur POP7

Antigène: POP7 (Processing of Precursor 7, Ribonuclease P/MRP Subunit (POP7))

Autre désignation: POP7 (POP7 Produits)

Synonymes: anticorps 0610037N12Rik, anticorps AI852017, anticorps Rpp20, anticorps RPP2, anticorps RPP20, anticorps POP7 homolog, ribonuclease P/MRP subunit, anticorps processing of precursor 7, ribonuclease P family, (S. cerevisiae), anticorps Pop7, anticorps POP7

Sujet: The nuclei of eukaryotic cells contain several classes of small RNA-protein complexes. SnRNPs (small nuclear ribonucleoproteins) are involved in splicing of pre-mRNAs (the excision of introns) in the nucleoplasm. RPP20 is part of such a complex. SnoRNPs (small nucleolar ribonucleoproteins) are involved in the maturation of pre-ribosomal RNA in the nucleoli. Pre-rRNA processing and modification require both the snoRNA and the protein constituents (such as Rpp20) of these complexes. Generally, snoRNPs contain a number of common proteins, which are shared with other snoRNPs of the same family, next to several particle-specific proteins. On average, snoRNPs contain about 6-10 protein subunits.Synonyms: RPP20, Ribonuclease P protein subunit p20, Ribonucleases P/MRP protein subunit POP7 homolog, hPOP7

Poids moléculaire: 20 kDa

ID gène: 10248

NCBI Accession: NP_005828

UniProt: O75817