Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)
Specificité
This antibody is directed to the common part of these proteins (PTPBR7, PTP-SL and PTPPBSγ). Specificity has been tested in Immunoprecipitation, Immunohistochemistry and Immunoblotting. Crossreacts with the striatum enriched phosphatase (STEP) when using antibody in Immunoblotting (Figure 1). Additional tests for cross reactivity have not yet been performed.
Réactivité croisée (Details)
Species reactivity (tested):Mouse.
Purification
Protein A Chromatography
Immunogène
Recombinant PTP-SL-GST (NCBI accession number BN000437, expression vector pGEX-2T), expressed in E.coli.
anticorps EC-PTP, anticorps PCPTP1, anticorps PTP-SL, anticorps PTPBR7, anticorps PTPRQ, anticorps Pcptp1, anticorps ec-ptp, anticorps pcptp1, anticorps ptp-sl, anticorps ptpbr7, anticorps PTPRR, anticorps Gmcp1, anticorps RPTPRR, anticorps mPTP213, anticorps protein tyrosine phosphatase, receptor type R, anticorps protein tyrosine phosphatase, receptor type, R, anticorps protein tyrosine phosphatase, receptor type R L homeolog, anticorps protein tyrosine phosphatase, receptor type, r, anticorps receptor-type tyrosine-protein phosphatase R, anticorps PTPRR, anticorps Ptprr, anticorps ptprr.L, anticorps ptprr, anticorps LOC100715069
Sujet
Protein tyrosine phosphatases (PTPs) are the enzymes that are instrumental in determining the spatial and temporal balance between the tyrosine phosphorylated and non-phosphorylated targets, and thus coordinately regulate these cellular responses to extracellular cues. The Ptprr gene gives rise to 4 different neuronal phosphatases which differ in length of their N-terminal part and subcellular localization. PTPBR7 (72 kDa) is receptor-like, PTP-SL (60 kDa) is membrane associated and PTPPBSγ (42 and 37 kDa) is a cytosolic phoaphatase.Synonyms: Ch-1PTPase, ECPTP, NC-PTPCOM1, PCPTP1, PTPRQ, Protein-tyrosine phosphatase PCPTP1, R-PTP-R, Receptor-type tyrosine-protein phosphatase R