Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
1.0 mg/mL
Buffer
PBS, 0.05 % Sodium Azide, 0.5 % protein stabilizer
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Antigène
RAP1A
(RAP1A, Member of RAS Oncogene Family (RAP1A))
Autre désignation
RAP1A
Sujet
The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50 % amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.Synonyms: C21KG, GTP-binding protein smg p21A, KREV-1, KREV1, RAP-1A, Ras-related protein Krev-1, Ras-related protein Rap-1A