ZIC2 anticorps (C-Term)

N° du produit ABIN1109557

Détail du produit anti-ZIC2 anticorps

Antigène: ZIC2

Épitope: C-Term

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp ZIC2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: C-HSGLSSNFNE WY

Specificité: This antibody detects ZIC2 (C-term) and is not expected to cross-react with other ZIC proteins.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Canine (Dog), Bovine.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogène: Peptide with sequence from the C-Terminus of Human ZIC2 (NP_009060.2). Genename: ZIC2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ZIC2

Antigène: ZIC2

Autre désignation: ZIC2 (ZIC2 Produits)

Synonymes: anticorps HPE5, anticorps Ku, anticorps cb851, anticorps fb26a03, anticorps wu:fb26a03, anticorps zic2, anticorps zic2.1, anticorps hpe5, anticorps hm:zeh0655, anticorps id:ibd5017, anticorps zic2.2, anticorps zic2l, anticorps Zic family member 2, anticorps zinc finger protein of the cerebellum 2, anticorps zic family member 2 (odd-paired homolog, Drosophila), a, anticorps Zic family member 2 L homeolog, anticorps zic family member 2 (odd-paired homolog, Drosophila) b, anticorps ZIC2, anticorps Zic2, anticorps zic2a, anticorps zic2.L, anticorps zic2b

Sujet: Zinc finger protein ZIC2 is a member of the GLI C2H2-type zinc-finger protein family. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Gene mutations cause holoprosencephaly type 5 in human brain and neural tube defects. Recent studies show that complete deficiency of the related murine ZIC2 transcription factor can also be a contributing factor to variable midline deficiencies, presenting during mid-gastrulation and similar forebrain anomalies.Synonyms: Zinc finger protein ZIC 2, Zinc finger protein of the cerebellum 2

ID gène: 7546

NCBI Accession: NP_009060

Pathways: Tube Formation