ZNF496 anticorps (Middle Region)

N° du produit ABIN1109595

Détail du produit anti-ZNF496 anticorps

Antigène: ZNF496 (Zinc Finger Protein 496 (ZNF496))

Épitope: Middle Region

Reactivité: Souris, Humain, Boeuf (Vache), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZNF496 est non-conjugé

Application: Western Blotting (WB)

Séquence: QEKPHECSVC GELFSDSEDL DGHLESHEAQ KPYRCGACGK SFRLNSHLLS

Réactivité croisée (Details): Species reactivity (expected):Mouse, Dog, BovineSpecies reactivity (tested):Human

Purification: Purified on peptide immunoaffinity column

Immunogène: Synthetic peptide directed towards the middle region of human ZNF496

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Add 50 μL of distilled water

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the lyophised antibody at -20 °C for up to one year. Store reconstitued antibody undiluted for one month or in aliquots at -20 °C long term.

Date de péremption: 12 months

Détails sur ZNF496

Antigène: ZNF496 (Zinc Finger Protein 496 (ZNF496))

Autre désignation: ZNF496 (ZNF496 Produits)

Synonymes: anticorps Zkscan17, anticorps Znf496, anticorps ZNF496, anticorps NIZP1, anticorps ZFP496, anticorps ZKSCAN17, anticorps ZSCAN49, anticorps BC040205, anticorps D130067D09, anticorps Nizp1, anticorps Zfp496, anticorps zinc finger protein 496, anticorps zinc finger with KRAB and SCAN domains 17, anticorps Zfp496, anticorps ZNF496, anticorps Zkscan17

Sujet: ZNF496 contains a SCAN box, a KRAB-A domain, and four consensus C2H2-type zinc fingers preceded by a unique finger derivative, referred to herein as the C2HR motif. The C2HR motif functions to mediate protein-protein interaction with the cysteine-rich (C5HCH) domain of NSD1 in a Zn(II)-dependent fashion, and when tethered to RNA polymerase II promoters, represses transcription in an NSD1-dependent manner. ZNF496 contains a novel type of zinc finger motif that functions as a docking site for NSD1 and is more than just a degenerate evolutionary remnant of a C2H2 motif.Synonyms: ZKSCAN17, Zinc finger protein 496, Zinc finger protein with KRAB and SCAN domains 17

ID gène: 84838

NCBI Accession: NP_116141