Bcl-2 anticorps

N° du produit ABIN1112797

Cet anticorps Souris Monoclonal détecte spécifiquement Bcl-2 dans WB, IHC, IHC (p) et ICC. Il présente une réactivité envers Souris.

Aperçu rapide pour Bcl-2 anticorps (ABIN1112797)

Antigène: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Bcl-2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Clone: D24-5

Détail du produit anti-Bcl-2 anticorps

Immunogène: Recombinant Bcl-2 protein.

Isotype: IgG2b

Information d'application

Indications d'application: WB (1:10,000), IHC-P (1:200), ICC (1:500). Other applications have not been tested. The optimal dilutions should be determined by end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.

Date de péremption: 12 months

Détails sur Bcl-2

Antigène: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Autre désignation: B-Cell Lymphoma 2, Bcl-2

Sujet: Bcl-2 (B-cell lymphoma 2) is the founding member of the Bcl-2 family of apoptosis regulator proteins encoded by the BCL2 gene. 1,2 Bcl-2 is an important regulator of photoreceptor cell death in retinal degenerations. 3 The bcl-2 protooncogene, which protects various cell types from apoptotic cell death, is expressed in the developing and adult nervous system. Bcl-2 may play an important role in survival of neurons both during development and throughout adult life. 4

Pathways: Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling