ITGB1 anticorps (C-Term, N-Term)

N° du produit ABIN112374

Cet anticorps anti-ITGB1 Monoclonal Souris (Clone 2B1) (ABIN112374) détecte spécifiquement ITGB1 dans WB, IF et IHC (fro). L’anticorps est réactif avec des échantillons de Humain, Souris, Porc et Chien.

Aperçu rapide pour ITGB1 anticorps (C-Term, N-Term) (ABIN112374)

Antigène: ITGB1 (Integrin beta 1 (ITGB1))

Reactivité: Humain, Souris, Porc, Chien

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ITGB1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 2B1

Détail du produit anti-ITGB1 anticorps

Épitope: C-Term, N-Term

Séquence: CQENPIYKS-PINNFKNPNY GRKAGL

Purification: Purified

Immunogène: A synthetic peptide corresponding to the C-terminal 24 amino acids of integrin b1D including an appending N-terminal cysteine coupled to keyhole limpet hemocyanin.

Isotype: IgG1

Information d'application

Indications d'application: Immunoblotting: 1: 100 - 1: 1000. Immunocytochemistry. Immunohistochemistry on frozen tissue: 1/25 -1/200 with an ABC method.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS with 0.09 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store undiluted (in aliquots) at -20 °C.

Détails sur ITGB1

Antigène: ITGB1 (Integrin beta 1 (ITGB1))

Autre désignation: CD29 / Integrin beta-1

Sujet: Integrins are a family of heterodimeric membrane glycoproteins consisting of non-covalently associated alpha and beta subunits. More than 18 alpha and 8 beta subunits with numerous splice variant isoforms have been identified in mammals. In general, integrins function as receptors for extracellular matrix proteins. Certain integrins can also bind to soluble ligands or to counter-receptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), resulting in aggregation of cells. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. There are two major forms of integrin beta1: beta1A and beta1D, which differ in 13 amino acids. Their distribution pattern in adult tissues is mutually exclusive. bea1A is present in all tissues, except cardiac and skeletal muscle, which instead express the beta1D variant.Synonyms: FNRB, Fibronectin receptor subunit beta, ITGB1, Integrin VLA-4 subunit beta, MDF2, MSK12

ID gène: 9606

UniProt: P05556

Pathways: Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome