CD8B anticorps
Aperçu rapide pour CD8B anticorps (ABIN114185)
Antigène
Voir toutes CD8B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This anti-mouse CD8 b-Chain monoclonal antibody is specific for most thymocytes, cytotoxic/suppressor T-cells and their precursors. The CD8 b-Chain is also named Ly-3.
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Purification
- Purified
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Isotype
- IgG2a
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Indications d'application
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Flow Cytometry Analysis (see Protocols).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Protocole
- FLOW CYTOMETRY ANALYSIS:
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Restrictions
- For Research Use only
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Concentration
- 0.2 mg/mL
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Buffer
- PBS and 0.1 % NaN3
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CD8B (CD8b Molecule (CD8B))
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Autre désignation
- CD8 beta
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Sujet
- The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.Synonyms: CD8B, CD8B1, T-cell surface glycoprotein CD8 beta chain
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ID gène
- 12526
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NCBI Accession
- NP_033988
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UniProt
- P10300
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Pathways
- TCR Signaling
Antigène
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