CCL2 anticorps (Biotin)

N° du produit ABIN114714

Cet anticorps anti-CCL2 est un anticorps Souris Monoclonal détectant CCL2 dans EIA. Adapté pour Humain.

Aperçu rapide pour CCL2 anticorps (Biotin) (ABIN114714)

Antigène: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CCL2 est conjugé à/à la Biotin

Application: Enzyme Immunoassay (EIA)

Clone: S101

Détail du produit anti-CCL2 anticorps (Biotin)

Purification: Protein G affinity purified

Immunogène: Purified recombinant human MCP-1

Isotype: IgG1

Information d'application

Indications d'application: ELISA: This Biotin-conjugated monoclonal antibody can be used as a tracer/detectionantibody in sandwich ELISA applications for human MCP-1 detection in combination with acapture antibody. Suggested Capture Coating Dose: approx. 0.3g/mL, Substrate: TMB. If theabove suggested conditions are followed approximately 1.5 pg/mL of MCP-1 inserum/plasma or 4 pg/mL of MCP-1 in medium can be detected with an assay range of0-1600 pg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.01 M PBS, pH 7.0±0.1, 0.1 % Proclin-300, 1 % Gelatin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Détails sur CCL2

Antigène: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Autre désignation: MCP1 / CCL2

Sujet: Monocyte chemotactic and activating factor (MCAF) is also called monocyte chemotactic protein-1 (MCP-1) and chemokine (C-C motif) ligand 2 (CCL2). It is primarily secreted by monocytes, macrophages and dendritic cells. This cytokine displays chemotactic activity for monocytes, T-cells, and basophils, but not for neutrophils or eosinophils. MCAF causes the degranulation of basophils and mast cells, and augments the activity of monocyte and macrophage. MCAF plays an important role in inflammation, angiogenesis, auto-immune diseases, renal diseases, chronic infection and granuloma formation.Synonyms: C-C motif chemokine 2, HC-11, HC11, MCAF, MCP-1, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, Monocyte chemotactic protein 1, Monocyte secretory protein JE, SCYA2, Small-inducible cytokine A2

ID gène: 9606

UniProt: P13500

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, Phosphorylation & l'infection par le SRAS-CoV-2