CCL2 anticorps (Biotin)
Aperçu rapide pour CCL2 anticorps (Biotin) (ABIN116137)
Antigène
Voir toutes CCL2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Affinity chromatography.
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Immunogène
- Highly pure (>98%) recombinant hMCP-1/MCAF (human Macrophage/Monocyte chemotactic protein-1).
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Indications d'application
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ELISA: To detect hMCP-1(MCAF) by direct ELISA (using 100 ml/well antibody solution) thisantibody can be used at a concentration of 0.15 - 0.30 μg/mL. Used in conjunction withcompatible secondary reagents, allows the detection of at least 0.2 ng/well of recombinanthMCP-1(MCAF). Western Blot: To detect hMCP-1(MCAF) by Western Blot analysis this antibody can be usedat a concentration of 0.1 - 0.2 mg/mL. Used in conjunction with compatible secondaryreagents the detection limit for recombinant hMCP-1(MCAF) is 1.5 - 3.0 ng/lane, undereither reducing or non-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Reconstitution
- Restore in sterile PBS containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL.
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Buffer
- PBS, pH 7.2 without preservatives.
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Agent conservateur
- Without preservative
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Conseil sur la manipulation
- Avoid repeated freezing and thawing. Centrifuge vial prior to opening!
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Stock
- -20 °C
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Stockage commentaire
- Store the antibody in aliquots at -20 °C after reconstitution.
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- CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
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Autre désignation
- MCP1 / CCL2
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Sujet
- This chemotactic factor attracts monocytes and basophils but not neutrophils or eosinophils and augments monocyte anti-tumor activity. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. It may be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.Synonyms: C-C motif chemokine 2, HC-11, HC11, MCAF, MCP-1, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, Monocyte chemotactic protein 1, Monocyte secretory protein JE, SCYA2, Small-inducible cytokine A2
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ID gène
- 9606
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UniProt
- P13500
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, Phosphorylation & l'infection par le SRAS-CoV-2
Antigène
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