NAMPT anticorps

N° du produit ABIN1169025

Cité dans 3 publications. Cet anticorps anti-NAMPT Polyclonal Lapin (ABIN1169025) détecte spécifiquement NAMPT dans WB, IHC et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour NAMPT anticorps (ABIN1169025)

Antigène: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NAMPT est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-NAMPT anticorps

Fonction: anti-Nampt (Visfatin/PBEF) (human), pAb

Specificité: Recognizes human Nampt. Weakly cross-reacts with mouse Nampt. Detects a band of ~54 kDa by Western blot.

Réactivité croisée (Details): Weakly cross-reacts with mouse Nampt.

Attributs du produit: Polyclonal Antibody. Recognizes human Nampt. Weakly cross-reacts with mouse Nampt. Detects a band of ~54 kDa by Western blot. Source: Rabbit. Applications: ELISA, IHC, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. Nampt also known as pre-B cell colony-enhancing factor 1 (PBEF1) or visfatin is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.

Stérilité: 0.2 μm filtered

Immunogène: Recombinant human Nampt (visfatin/PBEF).

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Agent conservateur: Without preservative

Conseil sur la manipulation: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire:

+4°C

-20°C

Stable for at least 6 months after receipt when stored at -20°C.

Date de péremption: 6 months

Références pour anticorps anti-NAMPT (ABIN1169025)

Moschen, Kaser, Enrich, Mosheimer, Theurl, Niederegger, Tilg: "Visfatin, an adipocytokine with proinflammatory and immunomodulating properties." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 3, pp. 1748-58, (2007) (PubMed).

Nowell, Richards, Fielding, Ognjanovic, Topley, Williams, Bryant-Greenwood, Jones: "Regulation of pre-B cell colony-enhancing factor by STAT-3-dependent interleukin-6 trans-signaling: implications in the pathogenesis of rheumatoid arthritis." dans: Arthritis and rheumatism, Vol. 54, Issue 7, pp. 2084-95, (2006) (PubMed).

Bae, Kim, Kim, Kim, Koo, Jang, Yun, Yoo, Bae: "Hypoxic induction of human visfatin gene is directly mediated by hypoxia-inducible factor-1." dans: FEBS letters, Vol. 580, Issue 17, pp. 4105-13, (2006) (PubMed).

Détails sur NAMPT

Antigène: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Autre désignation: Nampt (Visfatin/PBEF)

Sujet:

Alternate Names/Synonyms: Pre-B Cell Colony Enhancing Factor 1, PBEF1, Nicotinamide Phosphoribosyltransferase

Product Description: Nampt also known as pre-B cell colony-enhancing factor 1 (PBEF1) or visfatin is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.

UniProt: P43490