DLK1 anticorps (Extracellular Domain)

N° du produit ABIN1169184

Cité dans 1 publication. Cet anticorps anti-DLK1 Monoclonal Souris (Clone PF299-1) (ABIN1169184) détecte spécifiquement DLK1 dans WB, ELISA, IHC et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour DLK1 anticorps (Extracellular Domain) (ABIN1169184)

Antigène: DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DLK1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: PF299-1

Détail du produit anti-DLK1 anticorps

Épitope: Extracellular Domain

Fonction: anti-DLK1 (human), mAb (PF299-1)

Specificité: Recognizes human DLK1. Does not cross-react with mouse DLK1.

Aucune reactivité croisée: Souris

Réactivité croisée (Details): Does not cross-react with mouse DLK1.

Attributs du produit: Monoclonal Antibody. Recognizes human DLK1. Does not cross-react with mouse DLK1. Isotype: Mouse IgG1kappa. Clone: PF299-1. Applications: ELISA, FACS, IHC, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. The transmembrane and secreted protein delta-like 1 homolog (DLK1, Protein delta homolog 1, Preadipocyte factor 1, Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.

Stérilité: 0.2 μm filtered

Immunogène: Recombinant human DLK1 (extracellular domain).

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Agent conservateur: Without preservative

Conseil sur la manipulation: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Références pour anticorps anti-DLK1 (ABIN1169184)

Kluth, Radke, Kögler: "Increased Haematopoietic Supportive Function of USSC from Umbilical Cord Blood Compared to CB MSC and Possible Role of DLK-1." dans: Stem cells international, Vol. 2013, pp. 985285, (2013) (PubMed).

Détails sur DLK1

Antigène: DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))

Autre désignation: DLK1

Sujet:

Alternate Names/Synonyms: Protein Delta Homolog 1, Fetal Antigen 1, Preadipocyte Factor 1, Pref-1, FA1

Product Description: The transmembrane and secreted protein delta-like 1 homolog (DLK1, Protein delta homolog 1, Preadipocyte factor 1, Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.

UniProt: P80370