DLK1 anticorps (Extracellular Domain)
Aperçu rapide pour DLK1 anticorps (Extracellular Domain) (ABIN1169188)
Antigène
Voir toutes DLK1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Extracellular Domain
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Fonction
- anti-DLK1 (human), pAb
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Specificité
- Recognizes human DLK1. Detects a band of ~42 kDa by Western blot.
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Attributs du produit
- Polyclonal Antibody. Recognizes human DLK1. Detects a band of ~42 kDa by Western blot. Source: Rat. Applications: ELISA, FACS, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. The transmembrane and secreted protein delta-like 1 homolog (DLK1, Protein delta homolog 1, Preadipocyte factor 1, Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.
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Stérilité
- 0.2 μm filtered
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Immunogène
- Recombinant human DLK1 (extracellular domain).
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 0.2μm-filtered solution in PBS, pH 7.4.
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Agent conservateur
- Without preservative
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Conseil sur la manipulation
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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+4°C
-20°C
Stable for at least 6 months after receipt when stored at -20°C.
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Date de péremption
- 6 months
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- DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))
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Autre désignation
- DLK1
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Sujet
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Alternate Names/Synonyms: Protein Delta Homolog 1, Fetal Antigen 1, Preadipocyte Factor 1, Pref-1, FA1
Product Description: The transmembrane and secreted protein delta-like 1 homolog (DLK1, Protein delta homolog 1, Preadipocyte factor 1, Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.
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UniProt
- P80370
Antigène
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