DLK1 anticorps (Extracellular Domain)

N° du produit ABIN1169190

Cité dans 1 publication. Cet anticorps anti-DLK1 Monoclonal Rat (Clone PF105B) (ABIN1169190) détecte spécifiquement DLK1 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour DLK1 anticorps (Extracellular Domain) (ABIN1169190)

Antigène: DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp DLK1 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: PF105B

Détail du produit anti-DLK1 anticorps

Épitope: Extracellular Domain

Fonction: anti-DLK1 (mouse), mAb (PF105B)

Specificité: Recognizes mouse DLK1. Does not cross-react with human DLK1.

Aucune reactivité croisée: Humain

Réactivité croisée (Details): Does not cross-react with human DLK1.

Attributs du produit: Monoclonal Antibody. Recognizes mouse DLK1. Does not cross-react with human DLK1. Isotype: Rat IgG2akappa. Clone: PF105B. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. The transmembrane and secreted protein delta-like 1 homolog (DLK1, Protein delta homolog 1, Preadipocyte factor 1, Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.

Stérilité: 0.2 μm filtered

Immunogène: Recombinant mouse DLK1 (extracellular domain).

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: approx. 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Agent conservateur: Without preservative

Conseil sur la manipulation: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Références pour anticorps anti-DLK1 (ABIN1169190)

Kim, Kang, Park, Kim, Park, Kim, Leem, Chu, Lee, Jho, Oh: "Identification of a stroma-mediated Wnt/beta-catenin signal promoting self-renewal of hematopoietic stem cells in the stem cell niche." dans: Stem cells (Dayton, Ohio), Vol. 27, Issue 6, pp. 1318-29, (2009) (PubMed).

Détails sur DLK1

Antigène: DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))

Autre désignation: DLK1

Sujet:

Alternate Names/Synonyms: Protein Delta Homolog 1, Fetal Antigen 1, Preadipocyte Factor 1, Pref-1, FA1

Product Description: The transmembrane and secreted protein delta-like 1 homolog (DLK1, Protein delta homolog 1, Preadipocyte factor 1, Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.

UniProt: Q09163