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DLK1 anticorps

DLK1 Reactivité: Humain WB, ELISA, FACS, ICC Hôte: Souris Monoclonal 3A10 unconjugated
N° du produit ABIN969086
  • Antigène Voir toutes DLK1 Anticorps
    DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))
    Reactivité
    • 55
    • 42
    • 32
    • 17
    • 5
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 56
    • 7
    • 6
    Souris
    Clonalité
    • 59
    • 10
    Monoclonal
    Conjugué
    • 39
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DLK1 est non-conjugé
    Application
    • 61
    • 31
    • 23
    • 16
    • 13
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human DLK1 expressed in E. coli.
    Clone
    3A10
    Isotype
    IgG1
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Espina, Méndez-Vidal, Moreno-Mateos, Sáez, Romero-Franco, Japón, Pintor-Toro: "Induction of Dlk1 by PTTG1 inhibits adipocyte differentiation and correlates with malignant transformation." dans: Molecular biology of the cell, Vol. 20, Issue 14, pp. 3353-62, (2009) (PubMed).

    Katrincsakova, Takeda, Urbankova, Michaux, Jarosova, Vandenberghe, Georges, Charlier, Wlodarska: "Methylation analysis of the imprinted DLK1-GTL2 domain supports the random parental origin of the IGH-involving del(14q) in B-cell malignancies." dans: Epigenetics, Vol. 4, Issue 7, pp. 469-75, (2009) (PubMed).

  • Antigène
    DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))
    Autre désignation
    DLK1 (DLK1 Produits)
    Synonymes
    anticorps DELTA1, anticorps DL1, anticorps Delta, anticorps DLK, anticorps DLK-1, anticorps Delta1, anticorps FA1, anticorps PREF1, anticorps Pref-1, anticorps ZOG, anticorps pG2, anticorps AW742678, anticorps DlkI, anticorps Ly107, anticorps Peg9, anticorps SCP1, anticorps pref-1, anticorps Zog, anticorps delta like canonical Notch ligand 1, anticorps delta like non-canonical Notch ligand 1, anticorps delta-like 1 homolog (Drosophila), anticorps delta-like 1 (Drosophila), anticorps DLL1, anticorps DLK1, anticorps Dll1, anticorps Dlk1
    Sujet

    Description: This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes, it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance, this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass.

    Aliases: DLK, FA1, ZOG, pG2, PREF1, Pref-1

    Poids moléculaire
    41 kDa
    ID gène
    8788
    HGNC
    8788
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