RANKL anticorps
Aperçu rapide pour RANKL anticorps (ABIN1169326)
Antigène
Voir toutes RANKL (TNFSF11) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- anti-RANKL (human), pAb
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Specificité
- Recognizes human RANKL. Detects a band of ~35 kDa band by Western blot.
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Attributs du produit
- Polyclonal Antibody. Recognizes human RANKL. Detects a band of ~35 kDa band by Western blot. Source: Rabbit. Applications: ELISA, FACS, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. RANKL is an osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. Important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. Plays an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.
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Stérilité
- 0.2 μm filtered
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Immunogène
- Recombinant human RANKL.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 0.2μm-filtered solution in PBS, pH 7.4.
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Agent conservateur
- Without preservative
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Conseil sur la manipulation
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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+4°C
-20°C
Stable for at least 6 months after receipt when stored at -20°C.
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Date de péremption
- 6 months
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- RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))
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Autre désignation
- RANKL
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Sujet
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Alternate Names/Synonyms: TRANCE, ODF, OPGL, TNFSF11, CD254
Product Description: RANKL is an osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. Important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. Plays an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.
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UniProt
- O14788
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Pathways
- Signalisation NF-kappaB
Antigène
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